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List of works by Andy Chevigné

A Novel ACKR2-Dependent Role of Fibroblast-Derived CXCL14 in Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer

scientific article published on 08 March 2019

Activation mechanism of recombinant Der p 3 allergen zymogen: contribution of cysteine protease Der p 1 and effect of propeptide glycosylation

scientific article published on 25 August 2008

Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment

scientific article

Allosteric inhibition of VIM metallo-β-lactamases by a camelid nanobody

scientific article

Assessment of Biased Agonism among Distinct Synthetic Cannabinoid Receptor Agonist Scaffolds

scientific article published on 04 November 2019

Aurora A plays a dual role in migration and survival of human glioblastoma cells according to the CXCL12 concentration

scientific article published on 06 August 2018

Closing the Ring: A Fourth Extracellular Loop in Chemokine Receptors

scientific article published on 02 September 2014

Comparative study of mature and zymogen mite cysteine protease stability and pH unfolding

scientific article published on 8 June 2010

Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor

scientific article published on 8 July 2022

Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus

scientific article

Development of Mimokines, chemokine N terminus-based CXCR4 inhibitors optimized by phage display and rational design.

scientific article published on 23 March 2018

Different contribution of chemokine N-terminal features attest a different ligand binding mode and a bias towards activation of the atypical chemokine receptor ACKR3/CXCR7 compared to CXCR4 and CXCR3.

scientific article published on 22 December 2017

Emerging roles of the protease allergen Der p 1 in house dust mite-induced airway inflammation

scientific article published on 12 June 2018

Engineering and screening the N-terminus of chemokines for drug discovery

scientific article published on 30 July 2011

Function, diversity and therapeutic potential of the N-terminal domain of human chemokine receptors

scientific article published on 21 August 2012

GPCRs in immunity: Atypical receptors and novel concepts.

scientific article published on 29 June 2016

GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11

scientific article published on 21 September 2020

Human herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7.

scientific article published on 26 May 2016

Isolation of an HIV-1 neutralizing peptide mimicking the CXCR4 and CCR5 surface from the heavy-chain complementary determining region 3 repertoire of a viremic controller

scientific article published in January 2016

Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and endogenous non-chemokine agonists.

scientific article published on 9 March 2018

Neutralising properties of peptides derived from CXCR4 extracellular loops towards CXCL12 binding and HIV-1 infection

scientific article published on 27 January 2014

New integrative method to generate Bacillus subtilis recombinant strains free of selection markers

scientific article published on December 2004

New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model.

scientific article published on 19 April 2016

Orchestration of an uncommon maturation cascade of the house dust mite protease allergen quartet

scientific article published on 31 March 2014

Phages and HIV-1: from display to interplay

scientific article

Predominance of the heterozygous CCR5 delta-24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface

scientific article published on 01 September 2019

Profiling the Extended Cleavage Specificity of the House Dust Mite Protease Allergens Der p 1, Der p 3 and Der p 6 for the Prediction of New Cell Surface Protein Substrates.

scientific article

Relationship between propeptide pH unfolding and inhibitory ability during ProDer p 1 activation mechanism

scientific article published on 21 August 2007

Selection of a CXCR4 antagonist from a human heavy chain CDR3-derived phage library

scientific article

Structural Features of an Extended C-Terminal Tail Modulate the Function of the Chemokine CCL21

scientific article published on 26 March 2020

Structure prediction of GPCRs using piecewise homologs and application to the human CCR5 chemokine receptor: validation through agonist and antagonist docking

scientific article

Systematic reassessment of chemokine-receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL22

scientific article published on 01 June 2020

The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment

scientific article published on 18 June 2019

The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B

scientific article published on 01 January 2022

The Lys-Asp-Tyr Triad within the Mite Allergen Der p 1 Propeptide Is a Critical Structural Element for the pH-Dependent Initiation of the Protease Maturation

scientific article

The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides

scientific article published on 19 June 2020

The diverse and complex roles of atypical chemokine receptors in cancer: From molecular biology to clinical relevance and therapy

scientific article published on 14 February 2020

The proline-rich motif of the proDer p 3 allergen propeptide is crucial for protease-protease interaction

scientific article

The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma

scientific article published on 01 May 2019

Use of bifunctional hybrid beta-lactamases for epitope mapping and immunoassay development

scientific article

vCCL2/vMIP-II, the viral master KEYmokine

scientific article published on 23 December 2015

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