List of works - Hiroaki Itamochi

A Multi-Institutional Feasibility Study on the Use of Automated Screening Systems for Quality Control Rescreening of Cervical Cytology

scientific article published on 28 September 2016

A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer

scientific article

ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors

scientific article published on 15 May 2018

Activation of the Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Pathway Overcomes Cisplatin Resistance in Ovarian Carcinoma Cells ⬇️

scientific article published on July 1, 2012

Activity of docetaxel in paclitaxel-resistant ovarian cancer cells ⬇️

scientific article published on November 11, 2003

Adenovirus type 5 E1A gene therapy for ovarian clear cell carcinoma: a potential treatment strategy.

scientific article published on 11 January 2007

An open-label, randomized, phase II trial evaluating the efficacy and safety of standard of care with or without bevacizumab in platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer patients previously treated with beva

scientific article published on 31 July 2018

Apparent diffusion coefficient (ADC) measurement in ovarian tumor: Effect of region-of-interest methods on ADC values and diagnostic ability

scientific article published on 22 July 2015

Area under the curve calculation of nedaplatin dose used in combination chemotherapy with irinotecan in a phase I study of gynecologic malignancies ⬇️

scientific article published on May 18, 2012

Bcl-2 antisense oligonucleotide overcomes resistance to E1A gene therapy in a low HER2-expressing ovarian cancer xenograft model

scientific article published on September 2005

Bevacizumab and ovarian cancer

scientific article published on 01 February 2012

CD437 induces apoptosis in ovarian adenocarcinoma cells via ER stress signaling

scientific article published on 17 December 2007

Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C

scientific article published on 03 November 2020

Checkpoint kinase inhibitor AZD7762 overcomes cisplatin resistance in clear cell carcinoma of the ovary

scientific article published on January 2014

Chemotherapy consisting of paclitaxel and carboplatin benefits a patient with malignant mixed müllerian tumor of the fallopian tube

scientific article published on 23 October 2008

Clinical impact of systematic pelvic and para-aortic lymphadenectomy for pT1 and pT2 ovarian cancer: a retrospective survey by the Sankai Gynecology Study Group ⬇️

scientific article published on October 17, 2012

Clinical trials and future potential of targeted therapy for ovarian cancer ⬇️

scientific article published on August 28, 2012

Clinical tumor diameter and prognosis of patients with FIGO stage IB1 cervical cancer (JCOG0806-A).

scientific article published on 07 February 2015

Combination chemotherapy of oxaliplatin and 5-fluorouracil may be an effective regimen for mucinous adenocarcinoma of the ovary: a potential treatment strategy

scientific article

Contribution of transcription factor, SP1, to the promotion of HB-EGF expression in defense mechanism against the treatment of irinotecan in ovarian clear cell carcinoma.

scientific article

Cyclin A-associated kinase activity is needed for paclitaxel sensitivity

scientific article published in July 2005

Cytoplasmic Maspin Expression Correlates with Poor Prognosis of Patients with Adenocarcinoma of the Uterine Cervix

scientific article published on 18 December 2015

Development of Potent Forchlorfenuron Analogs and Their Cytotoxic Effect in Cancer Cell Lines

scientific article published on 24 February 2020

Dual inhibition of phosphatidylinositol 3'-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach for mucinous adenocarcinoma of the ovary

scientific article published on March 2014

Dual specificity phosphatase 6 as a new therapeutic target candidate for epithelial ovarian cancer

scientific article published on 01 December 2019

Effect of p53 gene transfer and cisplatin in a peritonitis carcinomatosa model with p53-deficient ovarian cancer cells

scientific article published in February 2002

Efficacy and safety of triple therapy with aprepitant, palonosetron, and dexamethasone for preventing nausea and vomiting induced by cisplatin-based chemotherapy for gynecological cancer: KCOG-G1003 phase II trial.

scientific article published on 14 May 2014

Establishment and characterization of a novel ovarian clear cell adenocarcinoma cell line, TU-OC-1, with a mutation in the PIK3CA gene

scientific article

Establishment and characterization of a novel ovarian clear cell carcinoma cell line, TU-OC-2, with loss of ARID1A expression

scientific article

Establishment and characterization of a novel ovarian serous adenocarcinoma cell line, TU-OS-4, that overexpresses EGFR and HER2 ⬇️

scientific article published on December 30, 2012

Establishment and characterization of a novel uterine carcinosarcoma cell line, TU-ECS-1, with mutations of TP53 and KRAS.

scientific article

Establishment and mutation analysis of a novel malignant peritoneal mesothelioma cell line, TU-MM-1, using whole genome sequencing

scientific article

Evaluating Chemotherapy-induced Nausea and Vomiting and Food Intake in Patients With Gynecologic Cancer

scientific article published on 01 August 2019

Evaluation of a formula for individual dosage of nedaplatin based on renal function

scientific article published on 15 September 2011

Expression of the c-myc gene as a predictor of chemotherapy response and a prognostic factor in patients with ovarian cancer

scientific article

Feasibility Study on Biweekly Paclitaxel Treatment as Maintenance Chemotherapy in Advanced Müllerian Carcinoma ⬇️

scientific article published on January 1, 2012

Feasibility study comparing docetaxel-cisplatin versus docetaxel-carboplatin as first-line chemotherapy for ovarian cancer

scientific article published on 10 January 2006

Feasibility study on combination chemotherapy using nogitecan hydrochloride (topotecan) and cisplatin for patients with metastatic, persistent, or recurrent uterine cervical cancer

scientific article

Fertility-sparing surgery for uterine cervical cancer

scientific article published on 31 August 2016

Fibroblast Growth Factor Receptor 2 Expression May Be Involved In Transformation of Ovarian Endometrioma to Clear Cell Carcinoma of the Ovary ⬇️

scientific article published on June 1, 2013

Fibroblast growth factor receptor 2 is associated with poor overall survival in clear cell carcinoma of the ovary and may be a novel therapeutic approach

scientific article published in May 2015

Gemcitabine and docetaxel in a patient with primary ovarian leiomyosarcoma: a case report and review of literature

scientific article published on 11 September 2017

Genome-wide analysis of microRNA to evaluate prognostic markers in isolated cancer glands and surrounding stroma in high-grade serous ovarian carcinoma

scientific article published on 08 October 2020

Germ cell specific protein VASA is over-expressed in epithelial ovarian cancer and disrupts DNA damage-induced G2 checkpoint

scientific article published on 20 September 2008

Gynecologic Cancer InterGroup (GCIG) consensus review for clear cell carcinoma of the ovary

scientific article

High-risk ovarian cancer based on 126-gene expression signature is uniquely characterized by downregulation of antigen presentation pathway.

scientific article published on 12 January 2012

Human papillomavirus type-specific persistence and reappearance after successful conization in patients with cervical intraepithelial neoplasia

scientific article

Immunohistochemical analysis of the epithelial to mesenchymal transition in uterine carcinosarcoma

scientific article published on 13 January 2019

Incidence and risk factors for lower limb lymphedema after gynecologic cancer surgery with initiation of periodic complex decongestive physiotherapy

scientific article

Inhibiting the mTOR Pathway Synergistically Enhances Cytotoxicity in Ovarian Cancer Cells Induced by Etoposide through Upregulation of c-Jun ⬇️

scientific article published on May 24, 2011

Inhibition of Aurora Kinase A Synergistically Enhances Cytotoxicity in Ovarian Clear Cell Carcinoma Cell Lines Induced by Cisplatin: A Potential Treatment Strategy

scientific article

Integrative kinome profiling identifies mTORC1/2 inhibition as treatment strategy in ovarian clear cell carcinoma.

scientific article published on 23 April 2018

Intraperitoneal carboplatin infusion may be a pharmacologically more reasonable route than intravenous administration as a systemic chemotherapy. A comparative pharmacokinetic analysis of platinum using a new mathematical model after intraperitoneal

scientific article published on 10 August 2005

Involvement of thioredoxin-binding protein 2 in the antitumor activity of CD437.

scientific article

Leptomycin B enhances CDDP-sensitivity via nuclear accumulation of p53 protein in HPV-positive cells

scientific article published on December 2003

Loss of ARID1A expression is associated with poor prognosis in patients with stage I/II clear cell carcinoma of the ovary

scientific article published on 06 March 2015

Low proliferation activity may be associated with chemoresistance in clear cell carcinoma of the ovary

scientific article

Measurement of endometrial thickness in premenopausal women in office gynecology.

scientific article published on 16 September 2017

Mechanisms of chemoresistance and poor prognosis in ovarian clear cell carcinoma

scientific article published on April 2008

Mechanisms of cisplatin resistance in clear cell carcinoma of the ovary

scientific article

Mesenteric extraovarian Sertoli-Leydig cell tumor without DICER1 hotspot mutation: a case report

scientific article published on 01 April 2019

Molecular targeted therapies for epithelial ovarian cancer

scientific article published on June 1, 2012

Multidrug resistance gene-1 is a useful predictor of Paclitaxel-based chemotherapy for patients with ovarian cancer

scientific article published on August 2002

Nedaplatin: a cisplatin derivative in cancer chemotherapy ⬇️

scientific article published on May 8, 2013

Neoadjuvant chemotherapy in advanced ovarian cancer: latest results and place in therapy

scientific article

Novel mechanism of reduced proliferation in ovarian clear cell carcinoma cells: Cytoplasmic sequestration of CDK2 by p27 ⬇️

scientific article published on June 8, 2011

Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusions

scientific article

Outcome of stage IB2-IIB patients with bulky uterine cervical cancer who underwent neoadjuvant chemotherapy followed by radical hysterectomy

scientific article

PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival

scientific article

PTEN expression is associated with prognosis for patients with advanced endometrial carcinoma undergoing postoperative chemotherapy

scientific article published on 01 August 2002

PTEN is involved in the signal transduction pathway of contact inhibition in endometrial cells

scientific article published on 8 November 2005

PTEN-positive and phosphorylated-Akt-negative expression is a predictor of survival for patients with advanced endometrial carcinoma

scientific article published on 01 August 2005

Predicting time to ovarian carcinoma recurrence using protein markers.

scientific article published on 15 August 2013

Predicting time to ovarian carcinoma recurrence using protein markers.

scientific article

Preoperative and intraoperative assessments of depth of myometrial invasion in endometrial cancer

scientific article published in July 2009

Protein expression patterns in cancer-associated fibroblasts and cells undergoing the epithelial-mesenchymal transition in ovarian cancers.

scientific article

Rapid progression of recurrent disease in a patient with renal cell carcinoma with vaginal metastasis

scientific article published on 07 July 2020

Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary

scientific article published on June 2002

Serum Vascular Endothelial Growth Factor-A as a Prognostic Biomarker for Epithelial Ovarian Cancer

scientific article published on 26 May 2017

Side population is increased in paclitaxel-resistant ovarian cancer cell lines regardless of resistance to cisplatin.

scientific article published on 26 January 2011

Simultaneous inhibition of the mitogen-activated protein kinase kinase and phosphatidylinositol 3'-kinase pathways enhances sensitivity to paclitaxel in ovarian carcinoma

scientific article

Somatic copy number alterations associated with Japanese or endometriosis in ovarian clear cell adenocarcinoma

scientific article

Stromal invasion of the cervix can be excluded from the criteria for using adjuvant radiotherapy following radical surgery for patients with cervical cancer

scientific article published on 01 June 2004

Struma ovarii with unique histological features: a case report

scientific article published on 01 November 2017

Surgical management of non-invasive uterine clear cell carcinoma.

scientific article published on July 2017

Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells

scientific article published on 04 January 2017

Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells

scientific article published on 22 September 2017

The PI3K/mTOR dual inhibitor NVP-BEZ235 reduces the growth of ovarian clear cell carcinoma

scientific article

Timing of G-CSF administration based on the circadian rhythm in patients with ovarian cancer

scientific article published on 01 June 2002

Whole-genome sequencing revealed novel prognostic biomarkers and promising targets for therapy of ovarian clear cell carcinoma.

scientific article published on 20 July 2017

List of works by Hiroaki Itamochi

A Multi-Institutional Feasibility Study on the Use of Automated Screening Systems for Quality Control Rescreening of Cervical Cytology

A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer

ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors

Activation of the Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Pathway Overcomes Cisplatin Resistance in Ovarian Carcinoma Cells ⬇️

Activity of docetaxel in paclitaxel-resistant ovarian cancer cells ⬇️

Adenovirus type 5 E1A gene therapy for ovarian clear cell carcinoma: a potential treatment strategy.

An open-label, randomized, phase II trial evaluating the efficacy and safety of standard of care with or without bevacizumab in platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer patients previously treated with beva

Apparent diffusion coefficient (ADC) measurement in ovarian tumor: Effect of region-of-interest methods on ADC values and diagnostic ability

Area under the curve calculation of nedaplatin dose used in combination chemotherapy with irinotecan in a phase I study of gynecologic malignancies ⬇️

Bcl-2 antisense oligonucleotide overcomes resistance to E1A gene therapy in a low HER2-expressing ovarian cancer xenograft model

Bevacizumab and ovarian cancer

CD437 induces apoptosis in ovarian adenocarcinoma cells via ER stress signaling

Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C

Checkpoint kinase inhibitor AZD7762 overcomes cisplatin resistance in clear cell carcinoma of the ovary

Chemotherapy consisting of paclitaxel and carboplatin benefits a patient with malignant mixed müllerian tumor of the fallopian tube

Clinical impact of systematic pelvic and para-aortic lymphadenectomy for pT1 and pT2 ovarian cancer: a retrospective survey by the Sankai Gynecology Study Group ⬇️

Clinical trials and future potential of targeted therapy for ovarian cancer ⬇️

Clinical tumor diameter and prognosis of patients with FIGO stage IB1 cervical cancer (JCOG0806-A).

Combination chemotherapy of oxaliplatin and 5-fluorouracil may be an effective regimen for mucinous adenocarcinoma of the ovary: a potential treatment strategy

Contribution of transcription factor, SP1, to the promotion of HB-EGF expression in defense mechanism against the treatment of irinotecan in ovarian clear cell carcinoma.

Cyclin A-associated kinase activity is needed for paclitaxel sensitivity

Cytoplasmic Maspin Expression Correlates with Poor Prognosis of Patients with Adenocarcinoma of the Uterine Cervix

Development of Potent Forchlorfenuron Analogs and Their Cytotoxic Effect in Cancer Cell Lines

Dual inhibition of phosphatidylinositol 3'-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach for mucinous adenocarcinoma of the ovary

Dual specificity phosphatase 6 as a new therapeutic target candidate for epithelial ovarian cancer

Effect of p53 gene transfer and cisplatin in a peritonitis carcinomatosa model with p53-deficient ovarian cancer cells

Efficacy and safety of triple therapy with aprepitant, palonosetron, and dexamethasone for preventing nausea and vomiting induced by cisplatin-based chemotherapy for gynecological cancer: KCOG-G1003 phase II trial.

Establishment and characterization of a novel ovarian clear cell adenocarcinoma cell line, TU-OC-1, with a mutation in the PIK3CA gene

Establishment and characterization of a novel ovarian clear cell carcinoma cell line, TU-OC-2, with loss of ARID1A expression

Establishment and characterization of a novel ovarian serous adenocarcinoma cell line, TU-OS-4, that overexpresses EGFR and HER2 ⬇️

Establishment and characterization of a novel uterine carcinosarcoma cell line, TU-ECS-1, with mutations of TP53 and KRAS.

Establishment and mutation analysis of a novel malignant peritoneal mesothelioma cell line, TU-MM-1, using whole genome sequencing

Evaluating Chemotherapy-induced Nausea and Vomiting and Food Intake in Patients With Gynecologic Cancer

Evaluation of a formula for individual dosage of nedaplatin based on renal function

Expression of the c-myc gene as a predictor of chemotherapy response and a prognostic factor in patients with ovarian cancer

Feasibility Study on Biweekly Paclitaxel Treatment as Maintenance Chemotherapy in Advanced Müllerian Carcinoma ⬇️

Feasibility study comparing docetaxel-cisplatin versus docetaxel-carboplatin as first-line chemotherapy for ovarian cancer

Feasibility study on combination chemotherapy using nogitecan hydrochloride (topotecan) and cisplatin for patients with metastatic, persistent, or recurrent uterine cervical cancer

Fertility-sparing surgery for uterine cervical cancer

Fibroblast Growth Factor Receptor 2 Expression May Be Involved In Transformation of Ovarian Endometrioma to Clear Cell Carcinoma of the Ovary ⬇️

Fibroblast growth factor receptor 2 is associated with poor overall survival in clear cell carcinoma of the ovary and may be a novel therapeutic approach

Gemcitabine and docetaxel in a patient with primary ovarian leiomyosarcoma: a case report and review of literature

Genome-wide analysis of microRNA to evaluate prognostic markers in isolated cancer glands and surrounding stroma in high-grade serous ovarian carcinoma

Germ cell specific protein VASA is over-expressed in epithelial ovarian cancer and disrupts DNA damage-induced G2 checkpoint

Gynecologic Cancer InterGroup (GCIG) consensus review for clear cell carcinoma of the ovary

High-risk ovarian cancer based on 126-gene expression signature is uniquely characterized by downregulation of antigen presentation pathway.

Human papillomavirus type-specific persistence and reappearance after successful conization in patients with cervical intraepithelial neoplasia

Immunohistochemical analysis of the epithelial to mesenchymal transition in uterine carcinosarcoma

Incidence and risk factors for lower limb lymphedema after gynecologic cancer surgery with initiation of periodic complex decongestive physiotherapy

Inhibiting the mTOR Pathway Synergistically Enhances Cytotoxicity in Ovarian Cancer Cells Induced by Etoposide through Upregulation of c-Jun ⬇️

Inhibition of Aurora Kinase A Synergistically Enhances Cytotoxicity in Ovarian Clear Cell Carcinoma Cell Lines Induced by Cisplatin: A Potential Treatment Strategy

Integrative kinome profiling identifies mTORC1/2 inhibition as treatment strategy in ovarian clear cell carcinoma.

Intraperitoneal carboplatin infusion may be a pharmacologically more reasonable route than intravenous administration as a systemic chemotherapy. A comparative pharmacokinetic analysis of platinum using a new mathematical model after intraperitoneal

Involvement of thioredoxin-binding protein 2 in the antitumor activity of CD437.

Leptomycin B enhances CDDP-sensitivity via nuclear accumulation of p53 protein in HPV-positive cells

Loss of ARID1A expression is associated with poor prognosis in patients with stage I/II clear cell carcinoma of the ovary

Low proliferation activity may be associated with chemoresistance in clear cell carcinoma of the ovary

Measurement of endometrial thickness in premenopausal women in office gynecology.

Mechanisms of chemoresistance and poor prognosis in ovarian clear cell carcinoma

Mechanisms of cisplatin resistance in clear cell carcinoma of the ovary

Mesenteric extraovarian Sertoli-Leydig cell tumor without DICER1 hotspot mutation: a case report

Molecular targeted therapies for epithelial ovarian cancer

Multidrug resistance gene-1 is a useful predictor of Paclitaxel-based chemotherapy for patients with ovarian cancer

Nedaplatin: a cisplatin derivative in cancer chemotherapy ⬇️

Neoadjuvant chemotherapy in advanced ovarian cancer: latest results and place in therapy

Novel mechanism of reduced proliferation in ovarian clear cell carcinoma cells: Cytoplasmic sequestration of CDK2 by p27 ⬇️

Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusions

Outcome of stage IB2-IIB patients with bulky uterine cervical cancer who underwent neoadjuvant chemotherapy followed by radical hysterectomy

PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival

PTEN expression is associated with prognosis for patients with advanced endometrial carcinoma undergoing postoperative chemotherapy

PTEN is involved in the signal transduction pathway of contact inhibition in endometrial cells

PTEN-positive and phosphorylated-Akt-negative expression is a predictor of survival for patients with advanced endometrial carcinoma

Predicting time to ovarian carcinoma recurrence using protein markers.

Predicting time to ovarian carcinoma recurrence using protein markers.

Preoperative and intraoperative assessments of depth of myometrial invasion in endometrial cancer

Protein expression patterns in cancer-associated fibroblasts and cells undergoing the epithelial-mesenchymal transition in ovarian cancers.

Rapid progression of recurrent disease in a patient with renal cell carcinoma with vaginal metastasis

Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary

Serum Vascular Endothelial Growth Factor-A as a Prognostic Biomarker for Epithelial Ovarian Cancer