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List of works by Thomas E Prisinzano

Addressing Structural Flexibility at the A-Ring on Salvinorin A: Discovery of a Potent Kappa-Opioid Agonist with Enhanced Metabolic Stability

scientific article

Assessment of rimonabant-like adverse effects of purported CB1R neutral antagonist / CB2R agonist aminoalkylindole derivatives in mice

scientific article published on 25 September 2018

Azaphilones inhibit tau aggregation and dissolve tau aggregates in vitro

scientific article published on 15 April 2015

Behavioral Effects and Central Nervous System Levels of the Broadly Available κ-Agonist Hallucinogen Salvinorin A Are Affected by P-Glycoprotein Modulation In Vivo ⬇️

scientific article published on March 20, 2012

Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats

scientific article published on 28 May 2015

Behavioral evaluation of modafinil and the abuse-related effects of cocaine in rhesus monkeys ⬇️

scientific article published on October 1, 2010

Benzylimidazolines as h5-HT1B/1D Serotonin Receptor Ligands: A Structure−Affinity Investigation ⬇️

scientific article published on June 18, 1998

Cannabinoid agonists increase the interaction between β-Arrestin 2 and ERK1/2 and upregulate β-Arrestin 2 and 5-HT2A receptors ⬇️

scientific article published on November 19, 2012

Correction to "Structure-Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias".

scientific article

Development of functionally selective, small molecule agonists at kappa opioid receptors

scientific article

Discovery of Small-Molecule Inhibitors Targeting the E3 Ubiquitin Ligase Activity of the Herpes Simplex Virus 1 ICP0 Protein Using an In Vitro High-Throughput Screening Assay

scientific article published on 14 June 2019

Effects of mesyl salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice

scientific article published on 26 February 2018

Further exploration of the structure-activity relationship of imidazoquinolines; identification of potent C7-substituted imidazoquinolines

scientific article published on 09 November 2019

High‐dose fenfluramine administration decreases serotonin transporter binding, but not serotonin transporter protein levels, in rat forebrain ⬇️

scientific article published on December 1, 2003

Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis

scientific article published on 6 September 2016

Impact of Pharmacological Manipulation of the κ-Opioid Receptor System on Self-grooming and Anhedonic-like Behaviors in Male Mice

scientific article published on 11 April 2019

Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents

scientific article published on 11 October 2018

Kappa opioid agonists reduce oxycodone self-administration in male rhesus monkeys

scientific article published on 31 January 2020

Modular Approach to pseudo-Neoclerodanes as Designer κ-Opioid Ligands.

scientific article

N-acetyl-S-(N,N-diethylcarbamoyl) cysteine in rat nucleus accumbens, medial prefrontal cortex, and in rat and human plasma after disulfiram administration

scientific article published on 25 January 2015

Nalfurafine promotes myelination <scp><i>in vitro</i></scp> and facilitates recovery from cuprizone + rapamycin‐induced demyelination in mice

NeuroChat with Professor Thomas E. Prisinzaro

scientific article published on 01 December 2020

Neuropharmacology of the Naturally Occurring κ-Opioid Hallucinogen Salvinorin A ⬇️

scientific article published on March 28, 2011

Novel psychotherapeutics - a cautiously optimistic focus on Hallucinogens.

scientific article

Opioid Receptor Probes Derived from Cycloaddition of the Hallucinogen Natural Product Salvinorin A ⬇️

scientific article published on February 21, 2011

Permeation and metabolism of cocaine in the nasal mucosa ⬇️

scientific article published on February 18, 2012

Pharmacology and anti-addiction effects of the novel κ opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A

scientific article

Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine

scientific article published on 06 September 2019

R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse

scientific article

Reinstatement of methamphetamine seeking in male and female rats treated with modafinil and allopregnanolone ⬇️

scientific article published on August 5, 2011

Role of Ventral Subiculum in Context-Induced Relapse to Alcohol Seeking after Punishment-Imposed Abstinence

scientific article published on March 2016

Scalable Regioselective and Stereoselective Synthesis of Functionalized (E)-4-Iodobut-3-en-1-ols: Gram-Scale Total Synthesis of Fungal Decanolides and Derivatives.

scientific article published on 22 December 2017

Semisynthesis and Kappa-Opioid Receptor Activity of Derivatives of Columbin, a Furanolactone Diterpene.

scientific article published on 18 July 2017

Semisynthetic neoclerodanes as kappa opioid receptor probes ⬇️

scientific article published on May 1, 2012

Strategies for developing kappa opioid receptor agonists for the treatment of pain with fewer side-effects

scientific article published on 10 September 2020

Structure-Activity Relationships at the Monoamine Transporters for a Novel Series of Modafinil (2-[(diphenylmethyl)sulfinyl]acetamide) Analogues

scientific article

Stuffed Methyltransferase Catalyzes the Penultimate Step of Pyochelin Biosynthesis

scientific article published on 27 December 2018

Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone

scientific article published on 2 March 2017

Synthesis and Opioid Activity of Tyr1 -ψ[(Z)CF=CH]-Gly2 and Tyr1 -ψ[(S)/(R)-CF3 CH-NH]-Gly2 Leu-enkephalin Fluorinated Peptidomimetics

scientific article

Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues

scientific article

Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability.

scientific article

Synthetic studies on neoclerodane diterpenes from Salvia splendens: oxidative modifications of ring A ⬇️

scientific article published on February 21, 2009

The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors

The analgesic and anti-inflammatory effects of Salvinorin A analogue β-tetrahydropyran Salvinorin B in mice.

scientific article published on 3 February 2017

The unique psychostimulant profile of (±)-modafinil: investigation of behavioral and neurochemical effects in mice

scientific article published on 22 August 2016

Time course of pharmacokinetic and hormonal effects of inhaled high-dose salvinorin A in humans

scientific article published on 15 February 2016

Utilizing Nature as a Source of New Probes for Opioid Pharmacology ⬇️

scientific article published on May 1, 2009

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