List of works - Thomas Kodadek

Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins

scientific article

A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity

scientific article

Isolation of protein ligands from large peptoid libraries

scientific article

Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening

scientific article

Target identification in chemical genetics: the (often) missing link

scientific article

Peptoids as potential therapeutics.

scientific article

Identification of a peptoid inhibitor of the proteasome 19S regulatory particle

scientific article published on 31 May 2007

Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries

scientific article

The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters

scientific article

A high-throughput assay for assessing the cell permeability of combinatorial libraries

scientific article published on 22 May 2005

High-throughput evaluation of relative cell permeability between peptoids and peptides

scientific article

Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins

scientific article published in November 2006

Synthesis and Screening of Stereochemically Diverse Combinatorial Libraries of Peptide Tertiary Amides

scientific article published on March 21, 2013

A biomimetic polyketide-inspired approach to small-molecule ligand discovery

scientific article

Protein "fingerprinting" in complex mixtures with peptoid microarrays

scientific article published on 25 August 2005

Design and synthesis of a cell-permeable synthetic transcription factor mimic

scientific article published on 27 May 2007

Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates

scientific article published on March 14, 2010

Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation

scientific article

NMR Analyses of the Activation of the Arp2/3 Complex by Neuronal Wiskott−Aldrich Syndrome Protein†

scientific article published on 01 November 2005

Quantum dots as a visual aid for screening bead-bound combinatorial libraries

scientific article published in November 2003

Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits

scientific article

No Splicing, no dicing: non-proteolytic roles of the ubiquitin-proteasome system in transcription

scientific article

Synthetic molecules as antibody replacements

scientific article

The proteasomal ATPase complex is required for stress-induced transcription in yeast

scientific article

MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting

scientific article

Periodate-triggered cross-linking of DOPA-containing peptide-protein complexes

scientific article published in September 2004

Isolation and characterization of coactivator-binding peptoids from a combinatorial library

scientific article published on 26 September 2006

Optimized protocols for the isolation of specific protein-binding peptides or peptoids from combinatorial libraries displayed on beads

scientific article

The rise, fall and reinvention of combinatorial chemistry

scientific article published on June 24, 2011

Transformation of low-affinity lead compounds into high-affinity protein capture agents

scientific article

Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries

scientific article

Physical and functional interactions of monoubiquitylated transactivators with the proteasome

scientific article published on 30 May 2008

Features of Modularly Assembled Compounds That Impart Bioactivity Against an RNA Target

scientific article published on September 13, 2013

A potent transactivation domain mimic with activity in living cells

scientific article published in June 2005

Label transfer chemistry for the characterization of protein-protein interactions

scientific article published on 26 September 2007

GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer

scientific article

Discovery of Peptoid Ligands for Anti-Aquaporin 4 Antibodies

scientific article published on March 21, 2013

Selective toxin sequestrants for the treatment of bacterial infections

scientific article

Small-molecule-based strategies for controlling gene expression

scientific article published on 01 June 1998

Transcription Activation by a PNA-Peptide Chimera in a Mammalian Cell Extract

scientific article published on October 1, 2003

Isolation of antagonists of antigen-specific autoimmune T cell proliferation

scientific article

Synthesis of libraries of peptidomimetic compounds containing a 2-oxopiperazine unit in the main chain

scientific article published on April 7, 2013

Acyl hydrazides as peptoid sub-monomers

scientific article

Identification of Gal4 activation domain-binding proteins in the 26S proteasome by periodate-triggered cross-linking

scientific article published on 30 September 2005

High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections

scientific article

A Liquid Array Platform for the Multiplexed Analysis of Synthetic Molecule–Protein Interactions

scientific article published on November 20, 2013

Synergistic Activation of Transcription by Physiologically Unrelated Transcription Factors through Cooperative DNA-Binding

scientific article published on June 18, 1998

Encoded combinatorial libraries for the construction of cyclic peptoid microarrays

scientific article

Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides

scientific article

The Immune System and Neuroinflammation as Potential Sources of Blood-Based Biomarkers for Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease

scientific article published on April 14, 2016

List of works by Thomas Kodadek

Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins

A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity

Isolation of protein ligands from large peptoid libraries

Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening

Target identification in chemical genetics: the (often) missing link

Peptoids as potential therapeutics.

Identification of a peptoid inhibitor of the proteasome 19S regulatory particle

Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries

The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters

A high-throughput assay for assessing the cell permeability of combinatorial libraries

High-throughput evaluation of relative cell permeability between peptoids and peptides

Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins

Synthesis and Screening of Stereochemically Diverse Combinatorial Libraries of Peptide Tertiary Amides

A biomimetic polyketide-inspired approach to small-molecule ligand discovery

Protein "fingerprinting" in complex mixtures with peptoid microarrays

Design and synthesis of a cell-permeable synthetic transcription factor mimic

Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates

Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation

NMR Analyses of the Activation of the Arp2/3 Complex by Neuronal Wiskott−Aldrich Syndrome Protein†

Quantum dots as a visual aid for screening bead-bound combinatorial libraries

Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits

No Splicing, no dicing: non-proteolytic roles of the ubiquitin-proteasome system in transcription

Synthetic molecules as antibody replacements

The proteasomal ATPase complex is required for stress-induced transcription in yeast

MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting

Periodate-triggered cross-linking of DOPA-containing peptide-protein complexes

Isolation and characterization of coactivator-binding peptoids from a combinatorial library

Optimized protocols for the isolation of specific protein-binding peptides or peptoids from combinatorial libraries displayed on beads

The rise, fall and reinvention of combinatorial chemistry

Transformation of low-affinity lead compounds into high-affinity protein capture agents

Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries

Physical and functional interactions of monoubiquitylated transactivators with the proteasome

Features of Modularly Assembled Compounds That Impart Bioactivity Against an RNA Target

A potent transactivation domain mimic with activity in living cells

Label transfer chemistry for the characterization of protein-protein interactions

GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer

Discovery of Peptoid Ligands for Anti-Aquaporin 4 Antibodies

Selective toxin sequestrants for the treatment of bacterial infections

Small-molecule-based strategies for controlling gene expression

Transcription Activation by a PNA-Peptide Chimera in a Mammalian Cell Extract

Isolation of antagonists of antigen-specific autoimmune T cell proliferation

Synthesis of libraries of peptidomimetic compounds containing a 2-oxopiperazine unit in the main chain

Acyl hydrazides as peptoid sub-monomers

Identification of Gal4 activation domain-binding proteins in the 26S proteasome by periodate-triggered cross-linking

High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections

A Liquid Array Platform for the Multiplexed Analysis of Synthetic Molecule–Protein Interactions

Synergistic Activation of Transcription by Physiologically Unrelated Transcription Factors through Cooperative DNA-Binding

Encoded combinatorial libraries for the construction of cyclic peptoid microarrays

Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides

The Immune System and Neuroinflammation as Potential Sources of Blood-Based Biomarkers for Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease