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List of works by Stephan Duparc

A Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Single Enantiomer (+)-Mefloquine Compared with Racemic Mefloquine in Healthy Persons ⬇️

scientific article published on December 1, 2010

A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum mal

scientific article published on 9 October 2017

A randomized trial of the prophylactic activity of DSM265 against pre-erythrocytic Plasmodium falciparum controlled human malaria infection by mosquito bites and direct venous inoculation

scientific article published on 5 December 2017

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study

article

Application of the Stable Isotope Label Approach in Clinical Development-Supporting Dissolution Specifications for a Commercial Tablet Product with Tafenoquine, a Long Half-life Compound

article

Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group

scientific article

Comprehensive case management of malaria: Operational research informing policy

scientific article published on 01 January 2019

Drug-Drug Interaction Analysis of Pyronaridine/Artesunate and Ritonavir in Healthy Volunteers ⬇️

scientific article published on March 1, 2012

Effects of Dihydroartemisinin-Piperaquine Phosphate and Artemether-Lumefantrine on QTc Interval Prolongation

scientific article published in Scientific Reports

Effects of body size and gender on the population pharmacokinetics of artesunate and its active metabolite dihydroartemisinin in pediatric malaria patients

scientific article published on 16 September 2013

Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial

scientific article

Efficacy and Safety of Fosmidomycin-Piperaquine as Nonartemisinin-Based Combination Therapy for Uncomplicated Falciparum Malaria: A Single-Arm, Age De-escalation Proof-of-Concept Study in Gabon

scientific article

Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data

scientific article published on 05 March 2020

Frequency of glucose-6-phosphate dehydrogenase deficiency in malaria patients from six African countries enrolled in two randomized anti-malarial clinical trials ⬇️

scientific article published on August 17, 2011

Improved access to early diagnosis and complete treatment of malaria in Odisha, India

scientific article published in PLoS ONE

Linking Murine and Human Plasmodium falciparum Challenge Models in a Translational Path for Antimalarial Drug Development

scientific article

Mass balance and metabolism of the antimalarial pyronaridine in healthy volunteers

scientific article published on 4 March 2014

Multiple-level stakeholder engagement in malaria clinical trials: addressing the challenges of conducting clinical research in resource-limited settings.

scientific article published on 22 March 2018

Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with Plasmodium Falciparum Parasitemia: An Open-Label, Non-Comparative Study in Sub-Saharan Africa

scientific article

Partnering to fight malaria in India: Past, present and future

scientific article published on 01 January 2019

Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects

scientific article published on 03 October 2016

Pharmacokinetic interactions and safety evaluations of coadministered tafenoquine and chloroquine in healthy subjects ⬇️

scientific article published on December 1, 2013

Population Pharmacokinetics of Tafenoquine, a Novel Antimalarial

scientific article published on 24 October 2018

Quantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group.

scientific article published on 20 June 2018

Randomised controlled trial of two sequential artemisinin-based combination therapy regimens to treat uncomplicated falciparum malaria in African children: a protocol to investigate safety, efficacy and adherence.

scientific article published on 30 August 2017

Randomized Placebo-Controlled Trial Evaluating the Ophthalmic Safety of Single-Dose Tafenoquine in Healthy Volunteers

scientific article published on 01 September 2019

Safety of a fixed-dose combination of artesunate and amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in real-life conditions of use in Côte d'Ivoire.

scientific article published on 03 January 2017

Safety, Tolerability, Pharmacokinetics, and Antimalarial Activity of the Novel Plasmodium Phosphatidylinositol 4-Kinase Inhibitor MMV390048 in Healthy Volunteers

scientific article published on 24 March 2020

Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria

scientific article published on 17 January 2019

Tafenoquine at therapeutic concentrations does not prolong Fridericia-corrected QT interval in healthy subjects

scientific article

Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria

scientific article published on 01 January 2019

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