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List of works by Lee Ratner

A phase 1/pharmacokinetic study of sunitinib in combination with highly active antiretroviral therapy in human immunodeficiency virus-positive patients with cancer: AIDS Malignancy Consortium trial AMC 061.

scientific article

Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.

scientific article

Akt Pathway Activation by Human T-cell Leukemia Virus Type 1 Tax Oncoprotein

scientific article

Animal models for human T-lymphotropic virus type 1 (HTLV-1) infection and transformation

scientific article

Arginine Residues in the C-terminus of HIV-1 Vpr Are Important for Nuclear Localization and Cell Cycle Arrest ⬇️

scientific article published on March 15, 1998

Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance

scientific article

Definition, prognostic factors, treatment, and response criteria of adult T-cell leukemia-lymphoma: a proposal from an international consensus meeting

scientific article published on 08 December 2008

Dose-adjusted EPOCH chemotherapy with bortezomib and raltegravir for human T-cell leukemia virus-associated adult T-cell leukemia lymphoma

scientific article published on 25 March 2016

Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF

scientific article published on 21 May 2021

Evidence for Common Structural Determinants of Human Immunodeficiency Virus Type 1 Coreceptor Activity Provided through Functional Analysis of CCR5/CXCR4 Chimeric Coreceptors ⬇️

scientific article published on December 1, 2001

Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways

scientific article

HIV-2 viral protein X (Vpx) ubiquitination is dispensable for ubiquitin ligase interaction and effects on macrophage infection ⬇️

scientific article published on March 3, 2012

HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1

scientific article published on 21 March 2019

HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice

scientific article published on 27 August 2017

Histone acetyltransferase (HAT) activity of p300 modulates human T lymphotropic virus type 1 p30II-mediated repression of LTR transcriptional activity

scientific article

Human T cell leukemia virus reactivation with progression of adult T-cell leukemia-lymphoma

scientific article

Human T-cell leukemia virus-associated malignancy

scientific article published on 31 August 2016

Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo.

scientific article

Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival

scientific article published on 16 July 2007

In vivo analysis of replication and immunogenicity of proviral clones of human T-lymphotropic virus type 1 with selective envelope surface-unit mutations

scientific article published on 26 July 2005

Integrase Inhibitors Effective against Human T-Cell Leukemia Virus Type 1 ⬇️

scientific article published on February 22, 2011

Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma

scientific article published on 28 August 2020

JAK blockade and HTLV ⬇️

scientific article published on February 10, 2011

Matrix Metalloproteinase Inhibitor COL-3 in the Treatment of AIDS-Related Kaposi’s Sarcoma: A Phase I AIDS Malignancy Consortium Study ⬇️

scientific article published on January 1, 2002

Molecular determinants of human T-lymphotropic virus type 1 transmission and spread

scientific article

Novel interactions between the HTLV antisense proteins HBZ and APH-2 and the NFAR protein family: Implications for the HTLV lifecycles

scientific article

PDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice.

scientific article published on 22 March 2018

Post-formulation peptide drug loading of nanostructures for metered control of NF-κB signaling ⬇️

scientific article published on January 1, 2011

Rapid Progression of Adult T-Cell Leukemia-Lymphoma after PD-1 Inhibitor Therapy

scientific article published on 01 May 2018

Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma

scientific article

Safety and Preliminary Efficacy of Vorinostat With R-EPOCH in High-risk HIV-associated Non-Hodgkin's Lymphoma (AMC-075).

scientific article published on 2 February 2018

T-cell activation promotes tumorigenesis in inflammation-associated cancer

scientific article

Targeting HTLV-1 Activation of NFκB in Mouse Models and ATLL Patients ⬇️

scientific article published on June 21, 2011

The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice

scientific article

The HTLV-1 hbz antisense gene indirectly promotes tax expression via down-regulation of p30II mRNA ⬇️

scientific article published on December 21, 2010

The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac ⬇️

scientific article published on February 10, 2012

The Tax Protein of Human T-cell Leukemia Virus Type 1 Mediates the Transactivation of the c-sis/Platelet-derived Growth Factor-B Promoter through Interactions with the Zinc Finger Transcription Factors Sp1 and NGFI-A/Egr-1 ⬇️

scientific article published on October 24, 1997

The human T-cell leukemia virus type-1 p30II protein activates p53 and induces the TIGAR and suppresses oncogene-induced oxidative stress during viral carcinogenesis

scientific article published on 17 February 2018

The use of new antiretroviral therapy in combination with chemotherapy ⬇️

scientific article published on September 1, 1997

Viral Protein R Regulates Docking of the HIV-1 Preintegration Complex to the Nuclear Pore Complex ⬇️

scientific article published on May 22, 1998

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