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List of works by Timothy P Cripe

"Buy one get one free": armed viruses for the treatment of cancer cells and their microenvironment

scientific article published on October 2009

A phase I trial and viral clearance study of reovirus (Reolysin) in children with relapsed or refractory extra-cranial solid tumors: a Children's Oncology Group Phase I Consortium report

scientific article

Adenovirus gene therapy for pediatric cancers: shall we gather at the liver?

scientific article

Aurora A kinase inhibition enhances oncolytic herpes virotherapy through cytotoxic synergy and innate cellular immune modulation

scientific article

Bortezomib-induced unfolded protein response increases oncolytic HSV-1 replication resulting in synergistic antitumor effects

scientific article

Can less really be more? Using lessons from leukemia and cancer stem cells to make sense of oral maintenance for metastatic sarcoma

scientific article published on April 2008

Cancer screening by systemic administration of a gene delivery vector encoding tumor-selective secretable biomarker expression

scientific article

Chondroitinase ABC I–Mediated Enhancement of Oncolytic Virus Spread and Antitumor Efficacy ⬇️

scientific article published on December 21, 2010

Cooperation of Oncolytic Herpes Virotherapy and PD-1 Blockade in Murine Rhabdomyosarcoma Models

scientific article

Cyclooxygenase-2 expression does not correlate with outcome in osteosarcoma or rhabdomyosarcoma.

scientific article published on April 2003

Doxorubicin synergizes with 34.5ENVE to enhance antitumor efficacy against metastatic ovarian cancer

scientific article

Drug targeting the actin cytoskeleton potentiates the cytotoxicity of low dose vincristine by abrogating actin-mediated repair of spindle defects

scientific article published on 08 April 2020

Efficacy and safety of the oncolytic herpes simplex virus rRp450 alone and combined with cyclophosphamide

scientific article

Emerging cancer-targeted therapies

scientific article

Ewing Sarcoma: An Eponym Window to History ⬇️

scientific article published on January 1, 2011

Going back to class I: MHC and immunotherapies for childhood cancer.

scientific article

High Mobility Group Box 1 Influences HSV1716 Spread and Acts as an Adjuvant to Chemotherapy

scientific article published on 15 March 2018

Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma

scientific article

Immune profiles of desmoplastic small round cell tumor and synovial sarcoma suggest different immunotherapeutic susceptibility upfront compared to relapse specimens

scientific article published on 17 July 2018

Immunotherapy for osteosarcoma: Where do we go from here?

scientific article published on 19 June 2018

Improving patient care: the use of a digital teaching file to enhance clinicians' access to the intellectual capital of interdepartmental conferences

scientific article published on February 2004

In Vivo Regulation of TGF-β by R-Ras2 Revealed through Loss of the RasGAP Protein NF1 ⬇️

scientific article published on August 23, 2012

Intratumoral Injection of HSV1716, an Oncolytic Herpes Virus, Is Safe and Shows Evidence of Immune Response and Viral Replication in Young Cancer Patients

scientific article published on 11 May 2017

MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.

scientific article

Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus

scientific article

Nothing but NET: a review of norepinephrine transporter expression and efficacy of 131I-mIBG therapy

scientific article

Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity.

scientific article published on 21 January 2015

Oncolytic HSV-1 Virotherapy: Clinical Experience and Opportunities for Progress ⬇️

scientific article published on July 1, 2012

Oncolytic virotherapy reaches adolescence

scientific article published on 23 August 2010

Oncolytic virus and PD-1/PD-L1 blockade combination therapy

scientific article published on 31 July 2018

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

scientific article

Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo

scientific article published on 17 February 2009

Pediatric cancer gone viral. Part I: strategies for utilizing oncolytic herpes simplex virus-1 in children.

scientific article

Pediatric cancer gone viral. Part II: potential clinical application of oncolytic herpes simplex virus-1 in children.

scientific article

Phase 1 study of intratumoral Pexa-Vec (JX-594), an oncolytic and immunotherapeutic vaccinia virus, in pediatric cancer patients

scientific article

Phase I trial of Seneca Valley Virus (NTX-010) in children with relapsed/refractory solid tumors: a report of the Children's Oncology Group

scientific article

Preclincial testing of Sorafenib and RAD001 in the Nfflox/flox;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging ⬇️

scientific article published on February 11, 2011

Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1.

scientific article

Preparation and Evaluation of a Novel Class of Amphiphilic Amines as Antitumor Agents and Nanocarriers for Bioactive Molecules

scientific article published on 25 July 2016

Promoting translational research in academic health centers: navigating the "roadmap".

scientific article

Radiation therapy may increase metastatic potential in alveolar rhabdomyosarcoma

scientific article published on 19 March 2015

Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target ⬇️

scientific article published on July 18, 2012

Saposin C coupled lipid nanovesicles enable cancer-selective optical and magnetic resonance imaging

scientific article

Shorter-duration therapy using vincristine, dactinomycin, and lower-dose cyclophosphamide with or without radiotherapy for patients with newly diagnosed low-risk rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Onc

scientific article

Statistical issues in longitudinal data analysis for treatment efficacy studies in the biomedical sciences

scientific article

Targeting cancer-initiating cells with oncolytic viruses

scientific article

The effect of emerging molecular and genetic therapies on cardiopulmonary disease in Duchenne muscular dystrophy

scientific article published on 03 November 2020

Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors

scientific article

To Infection and Beyond: The Multi-Pronged Anti-Cancer Mechanisms of Oncolytic Viruses

scientific article

Tumor-Associated Macrophages in Oncolytic Virotherapy: Friend or Foe?

scientific article published on 7 July 2016

Use of miRNA response sequences to block off-target replication and increase the safety of an unattenuated, glioblastoma-targeted oncolytic HSV

scientific article published on 9 September 2014

VEGF blockade enables oncolytic cancer virotherapy in part by modulating intratumoral myeloid cells

scientific article

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