List of works - Salil A Lachke

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects

scientific article published on 14 June 2021

A systematic genetic analysis and visualization of phenotypic heterogeneity among orofacial cleft GWAS signals

scientific article published on 06 June 2019

An integrative approach to analyze microarray datasets for prioritization of genes relevant to lens biology and disease

scientific article published in August 2015

Building the developmental oculome: systems biology in vertebrate eye development and disease ⬇️

scientific article published on May 1, 2010

Deficiency of the RNA binding protein caprin2 causes lens defects and features of Peters anomaly

scientific article

Genomic analyses in African populations identify novel risk loci for cleft palate

scientific article published on 01 March 2019

High-throughput transcriptome analysis reveals that the loss of Pten activates a novel NKX6-1/RASGRP1 regulatory module to rescue microphthalmia caused by Fgfr2-deficient lenses

scientific article published on 05 November 2019

MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract

scientific article published on 03 December 2019

Modeling ocular lens disease in Xenopus

scientific article published on 24 December 2019

Molecular characterization of the human lens epithelium-derived cell line SRA01/04

scientific article published on 31 August 2019

Mutation update of transcription factor genes FOXE3, HSF4, MAF, and PITX3 causing cataracts and other developmental ocular defects.

scientific article published on 4 January 2018

Mutations in GDF11 and the extracellular antagonist, Follistatin, as a likely cause of Mendelian forms of orofacial clefting in humans

scientific article published on 18 June 2019

N-myc regulates growth and fiber cell differentiation in lens development

scientific article published on 14 July 2017

Pathogenic variants in PLOD3 result in a Stickler syndrome-like connective tissue disorder with vascular complications

scientific article published on 25 May 2019

RNA sequencing-based transcriptomic profiles of embryonic lens development for cataract gene discovery

scientific article published on 11 November 2018

The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development.

scientific article published on 22 March 2018

The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development

scientific article published on 27 June 2020

Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations

scientific article published on 14 September 2017

iSyTE 2.0: a database for expression-based gene discovery in the eye.

scientific article published on 19 September 2017

List of works by Salil A Lachke