List of works - Steffi Oesterreich

A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

scientific article published on 24 February 2022

A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs

scientific article published on 03 July 2020

Association of Variants in Candidate Genes with Lipid Profiles in Women with Early Breast Cancer on Adjuvant Aromatase Inhibitor Therapy

scientific article published on 13 October 2015

Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover

scientific article published on 4 November 2015

Atlas of Lobular Breast Cancer Models: Challenges and Strategic Directions

scientific article published on 28 October 2021

B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma

scientific article published on 07 June 2021

Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures

scientific article published on 18 September 2018

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

scientific article published on 30 November 2017

ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation

scientific article published on 19 April 2022

Estrogen receptor alpha mutations in breast cancer cells cause gene expression changes through constant activity and secondary effects

scientific article published on 12 November 2020

FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype

scientific article published on 27 June 2019

Frequent ESR1 and CDK Pathway Copy Number Alterations in Metastatic Breast Cancer

article

Functional interaction of histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) promotes breast cancer progression.

scientific article published on 23 May 2016

Genetic associations with toxicity-related discontinuation of aromatase inhibitor therapy for breast cancer

scientific article published on 2 April 2013

Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment

scientific article published in 2023

Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade

scientific article published on 15 August 2018

Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism.

scientific article

Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer

scientific article published on 04 September 2018

Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities

scientific article published on 26 January 2022

Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models.

scientific article

Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer

scientific article published on 10 May 2022

Publisher Correction: Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment

scientific article published in 2023

Results of a worldwide survey on the currently used histopathological diagnostic criteria for invasive lobular breast cancer

scientific article published in 2022

SNAIL is induced by tamoxifen and leads to growth inhibition in invasive lobular breast carcinoma

scientific article published on 23 February 2019

Single-cell transcriptomic heterogeneity in invasive ductal and lobular breast cancer cells

scientific article published on 04 November 2020

Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations

scientific article published on 23 July 2024

Steroid hormone receptor and infiltrating immune cell status reveals therapeutic vulnerabilities of ESR1 mutant breast cancer