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List of works by Casper Steenholdt

A role for thiopurine metabolites in the synergism between thiopurines and infliximab in inflammatory bowel disease

scientific article published on 14 November 2017

Absence of Relationship Between Crohn's Disease Activity Index or C-Reactive Protein and Infliximab Exposure Calls for Objective Crohn's Disease Activity Measures for the Evaluation of Treatment Effects at Treatment Failure

scientific article published in April 2019

Absence of relationship between CDAI or CRP and infliximab exposure calls for objective Crohn's disease activity measures for the evaluation of treatment effects at treatment failure

scientific article published on 26 December 2018

Acute and delayed hypersensitivity reactions to infliximab and adalimumab in a patient with Crohn's disease

scientific article published on 31 August 2011

Antibodies against infliximab are associated with de novo development of antibodies to adalimumab and therapeutic failure in infliximab-to-adalimumab switchers with IBD

scientific article published on 01 October 2014

Changes in serum trough levels of infliximab during treatment intensification but not in anti-infliximab antibody detection are associated with clinical outcomes after therapeutic failure in Crohn's disease

scientific article published on 09 January 2015

Circulating Cytokines and Cytokine Receptors in Infliximab Treatment Failure Due to TNF-α Independent Crohn Disease

scientific article published on April 2016

Clinical implications of measuring drug and anti-drug antibodies by different assays when optimizing infliximab treatment failure in Crohn's disease: post hoc analysis of a randomized controlled trial

scientific article published on 6 May 2014

Clinical implications of variations in anti-infliximab antibody levels in patients with inflammatory bowel disease

scientific article published on 16 February 2012

Clinical outcome of adalimumab therapy in patients with ulcerative colitis previously treated with infliximab: a Danish single-center cohort study

scientific article published on 10 April 2015

Comparison of techniques for monitoring infliximab and antibodies against infliximab in Crohn's disease

scientific article published in August 2013

Cut-off levels and diagnostic accuracy of infliximab trough levels and anti-infliximab antibodies in Crohn's disease

scientific article published on 18 November 2010

Discontinuation of infliximab therapy in patients with Crohn's disease in sustained complete remission (the STOP IT study): protocol for a double-blind, randomised, placebo-controlled, multicentre trial

scientific article

Doubling the infliximab dose versus halving the infusion intervals in Crohn's disease patients with loss of response.

scientific article published on 31 January 2012

Efficacy and safety of methotrexate in the management of inflammatory bowel disease: A systematic review and meta-analysis of randomized, controlled trials

scientific article published on 04 February 2020

Expression and function of toll-like receptor 8 and Tollip in colonic epithelial cells from patients with inflammatory bowel disease

scientific article published in January 2009

Implications of Infliximab Treatment Failure and Influence of Personalized Treatment on Patient-reported Health-related Quality of Life and Productivity Outcomes in Crohn's Disease.

scientific article published on 5 August 2015

Individual medicine in inflammatory bowel disease: monitoring bioavailability, pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies

scientific article published on January 2009

Individualised therapy is more cost-effective than dose intensification in patients with Crohn's disease who lose response to anti-TNF treatment: a randomised, controlled trial

scientific article published on 22 July 2013

Individualized Therapy Is a Long-Term Cost-Effective Method Compared to Dose Intensification in Crohn's Disease Patients Failing Infliximab.

scientific article published on 12 February 2015

Infliximab clearance decreases in the second and third trimesters of pregnancy in inflammatory bowel disease

scientific article published on 20 October 2020

Interactions Between Thiopurine Metabolites, Adalimumab, and Antibodies Against Adalimumab in Previously Infliximab-Treated Patients with Inflammatory Bowel Disease

scientific article published on 21 March 2018

Letter: can addition of an immunomodulator really reverse antibody formation and loss of response in patients treated with adalimumab?

scientific article published in March 2017

Magnitude of Increased Infliximab Clearance Imposed by Anti-infliximab Antibodies in Crohn's Disease Is Determined by Their Concentration

scientific article published on 13 October 2016

Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

scientific article published on 16 October 2017

Methotrexate for inflammatory bowel disease: time for reconsideration

scientific article published on 21 March 2019

Microbiotas from UC patients display altered metabolism and reduced ability of LAB to colonize mucus

scientific article published on 23 January 2013

Monitoring immunogenicity of protein-based TNF antagonists

scientific article published on 14 May 2015

Optimizing Treatment with TNF Inhibitors in Inflammatory Bowel Disease by Monitoring Drug Levels and Antidrug Antibodies.

scientific article published on 29 April 2016

Outcome after discontinuation of infliximab in patients with inflammatory bowel disease in clinical remission: an observational Danish single center study

scientific article published in March 2012

Outcome of continued infliximab therapy in Crohn's disease patients with response but without remission after one year of infliximab - a retrospective cohort study.

scientific article published on 10 July 2018

Outcomes After Primary Infliximab Treatment Failure in Inflammatory Bowel Disease.

scientific article published in July 2017

Patient Satisfaction of Propofol Versus Midazolam and Fentanyl Sedation During Colonoscopy in Inflammatory Bowel Disease

scientific article published on 22 October 2020

Personalized therapy with TNF-inhibitors in Crohn's disease: optimizing treatment outcomes by monitoring drug levels and anti-drug antibodies

scientific article

Pharmacology and Optimization of Thiopurines and Methotrexate in Inflammatory Bowel Disease.

scientific article published on 09 August 2015

Prevention of infections in patients with inflammatory bowel disease during TNF inhibitor treatment ⬇️

scientific article published on November 2014

Proactive and Reactive Therapeutic Drug Monitoring of Biologic Therapies in Inflammatory Bowel Disease Are Complementary, Not Mutually Exclusive

scientific article published on 01 April 2018

Putative biomarkers of vedolizumab resistance and underlying inflammatory pathways involved in IBD.

scientific article published on 31 May 2018

Reply to letter by Dr. Hewson: "Procedural sedation for colonoscopy: a role for patient-maintained propofol sedation?"

scientific article published on 15 December 2020

Reporter gene assay for the quantification of the activity and neutralizing antibody response to TNFα antagonists

scientific article published on 03 September 2011

Systematic Information to Health-Care Professionals about Vaccination Guidelines Improves Adherence in Patients With Inflammatory Bowel Disease in Anti-TNFα Therapy

scientific article

The role and advances of immunomodulator therapy for inflammatory bowel disease

scientific article published on 07 August 2014

Therapeutic infliximab drug level in a child born to a woman with ulcerative colitis treated until gestation week 31

scientific article published on 28 October 2011

Therapeutic thresholds and mechanisms for primary non-response to infliximab in inflammatory bowel disease

scientific article published on 06 July 2020

Time Course and Clinical Implications of Development of Antibodies Against Adalimumab in Patients With Inflammatory Bowel Disease.

scientific article published in July 2016

Transient and Persistent Antibodies Against TNF-Inhibitors in IBD

scientific article published on 01 November 2015

Use of infliximab and anti-infliximab antibody measurements to evaluate and optimize efficacy and safety of infliximab maintenance therapy in Crohn's disease

scientific article published on April 2013

[Monitoring of bioavailability, pharmacokinetics and immunogenicity of tumour necrosis factor-alpha inhibitors]

scientific article published on 01 January 2010

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