Search filters

List of works by Steven H. Liang

"In-loop" [11 C]CO2 fixation: Prototype and proof of concept

scientific article published on 9 June 2017

(11)C[double bond, length as m-dash]O bonds made easily for positron emission tomography radiopharmaceuticals

scientific article

11CO2 fixation: a renaissance in PET radiochemistry.

scientific article published on 14 May 2013

18 F-Labeling of Sensitive Biomolecules for Positron Emission Tomography.

scientific article

A Facile Radiolabeling of [18F]FDPA via Spirocyclic Iodonium Ylides: Preliminary PET Imaging Studies in Preclinical Models of Neuroinflammation

scientific article published on 22 May 2017

A concisely automated synthesis of TSPO radiotracer [18 F]FDPA based on spirocyclic iodonium ylide method and validation for human use

scientific article published on 20 January 2020

A metal protein-attenuating compound for PET neuroimaging: Synthesis and preclinical evaluation of [11C]PBT2.

scientific article published on 3 January 2018

Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque.

scientific article published on 11 December 2013

Assessment of cholesterol homeostasis in the living human brain

scientific article published in 2022

C(sp³)-¹⁸F bond formation by transition-metal-based [¹⁸F]fluorination

scientific article published on 22 September 2014

Chemistry for Positron Emission Tomography: Recent Advances in 11 C-, 18 F-, 13 N-, and 15 O-Labeling Reactions

scientific article published on 14 January 2019

Classics in Neuroimaging: Imaging the Endocannabinoid Pathway with PET

scientific article published on 19 June 2020

Design, Synthesis, and Evaluation of 18F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes

scientific article published on 26 September 2019

Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton

scientific article published on 21 March 2019

Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging.

scientific article published on 2 February 2017

Discovery and Optimization of α-Mangostin Derivatives as Novel PDE4 Inhibitors for the Treatment of Vascular Dementia

scientific article published on 12 March 2020

Facile 18F labeling of non-activated arenes via a spirocyclic iodonium(III) ylide method and its application in the synthesis of the mGluR5 PET radiopharmaceutical [18F]FPEB

scientific article published on 12 April 2019

Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2)

scientific article published on 22 September 2020

In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies

scientific article published on 26 February 2018

Iodonium ylide-mediated radiofluorination of 18F-FPEB and validation for human use

scientific article published on 05 February 2015

Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy

scientific article published on 08 June 2020

Microfluidic radiosynthesis of [18F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors.

scientific article published on 29 December 2017

PET imaging of fatty acid amide hydrolase with [(18)F]DOPP in nonhuman primates

scientific article

PET neuroimaging studies of [(18)F]CABS13 in a double transgenic mouse model of Alzheimer's disease and nonhuman primates

scientific article (publication date: 15 April 2015)

Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N-Methyl-d-aspartate (NMDA), α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA), and Kainate Re

scientific article published on 27 August 2018

Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development

scientific article published on 30 December 2020

Preclinical PET Neuroimaging of [11C]Bexarotene.

scientific article published on 23 August 2016

Recent applications of a single quadrupole mass spectrometer in C, F and radiometal chemistry

Ru-Photoredox-Catalyzed Decarboxylative Oxygenation of Aliphatic Carboxylic Acids through N-(acyloxy)phthalimide

scientific article published on 02 August 2018

Selected PET Radioligands for Ion Channel Linked Neuroreceptor Imaging: Focus on GABA, NMDA and nACh Receptors

scientific article published on 15 March 2016

Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics.

scientific article published on 9 July 2014

Structural Basis for Achieving GSK-3β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery

scientific article published on 21 October 2019

Synthesis and Preliminary Evaluation of 11 C‐Labeled VU0467485/AZ13713945 and Its Analogues for Imaging Muscarinic Acetylcholine Receptor Subtype 4

scientific article published on 27 December 2018

Synthesis and Preliminary Evaluation of [11 C]GNE-1023 as a Potent PET Probe for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2) in Parkinson's Disease

scientific article published on 22 August 2019

Synthesis and Preliminary Evaluations of a Triazole-Cored Antagonist as a PET Imaging Probe ([18F]N2B-0518) for GluN2B Subunit in the Brain

scientific article published on 27 February 2019

Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[11C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 2.

scientific article

Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib

scientific article

Synthesis of [(11)C]Bexarotene by Cu-Mediated [(11)C]Carbon Dioxide Fixation and Preliminary PET Imaging

scientific article

Synthesis, pharmacology and preclinical evaluation of C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein

scientific article published on 5 September 2018

Synthesis-free PET imaging of brown adipose tissue and TSPO via combination of disulfiram and 64CuCl2.

scientific article published on 15 August 2017

The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils

scholarly article by Lee Josephson et al published January 2018 in Molecular imaging : official journal of the Society for Molecular Imaging

Total Radiosynthesis: Thinking outside "the box"

scientific article

Visible-light induced decarboxylative coupling of redox-active esters with disulfides to construct C-S bonds

scientific article published on 24 March 2020