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List of works by Wieland B Huttner

3' UTR-dependent, miR-92-mediated restriction of Tis21 expression maintains asymmetric neural stem cell division to ensure proper neocortex size.

scientific article published on 13 April 2014

A genomic toolkit to investigate kinesin and myosin motor function in cells

scientific article

A new approach to manipulate the fate of single neural stem cells in tissue

scientific article

A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex

scientific article published on 18 October 2018

A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification

scientific article published on 07 December 2016

A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons

scientific article published on 13 February 2020

A tunable refractive index matching medium for live imaging cells, tissues and model organisms.

scientific article published on 14 July 2017

AC133 antigen, CD133, prominin-1, prominin-2, etc.: prominin family gene products in need of a rational nomenclature.

scientific article published in January 2003

ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules. ⬇️

scientific article published on 25 August 2016

ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.

scientific article published on October 2017

Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis.

scholarly article

Abnormal spindle-like microcephaly-associated (ASPM) mutations strongly disrupt neocortical structure but spare the hippocampus and long-term memory

scientific article published on 31 October 2015

Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus.

scientific article published on 23 November 2011

An adaptive threshold in mammalian neocortical evolution

scientific article

An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis

scientific article published in December 2003

Analysis of primary cilia in the developing mouse brain

scientific article published on 14 February 2015

Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells

scientific article

Asymmetric cell division during neurogenesis in Drosophila and vertebrates.

scientific article published on November 2003

Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells

scientific article

Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division

scientific article

Autonomic function in hypertension; role of genetic variation at the catecholamine storage vesicle protein chromogranin B

scientific article

Basal process and cell divisions of neural progenitors in the developing brain

scientific article published on April 2009

Basolateral rather than apical primary cilia on neuroepithelial cells committed to delamination ⬇️

scientific article published on November 17, 2011

Brain organoids as models to study human neocortex development and evolution

scientific article published on 10 July 2018

Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors

scientific article published on 29 April 2009

CORRECTIONS: XLαs is a new type of G protein

scientific article published in Nature

CRISPR/Cas9-induced disruption of gene expression in mouse embryonic brain and single neural stem cells in vivo.

scientific article

Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors.

scientific article published on September 2009

Cell polarity from cell division

scientific article

Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1

scientific article (publication date: 7 February 2003)

Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins

scientific article

Chromogranin B gene ablation reduces the catecholamine cargo and decelerates exocytosis in chromaffin secretory vesicles.

scientific article

Clever space saving—how the cerebral cortex folds

scientific article

Comment on "Cortical folding scales universally with surface area and thickness, not number of neurons".

scientific article published on February 2016

Conical expansion of the outer subventricular zone and the role of neocortical folding in evolution and development ⬇️

scientific article published on January 1, 2013

Convergent repression of Foxp2 3'UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons.

scientific article

Cortical progenitor expansion, self-renewal and neurogenesis-a polarized perspective

scientific article published on October 29, 2010

Cytokinesis of neuroepithelial cells can divide their basal process before anaphase

scientific article

Defective secretion of islet hormones in chromogranin-B deficient mice

scientific article

Detection and monitoring of microRNA expression in developing mouse brain and fixed brain cryosections

scientific article published in January 2014

Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development

scientific article (publication date: 26 September 2016)

Differential expression of Prominin-1 (CD133) and Prominin-2 in major cephalic exocrine glands of adult mice

scientific article published on 14 September 2007

Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species

scientific article

Doxycycline-dependent photoactivated gene expression in eukaryotic systems

scientific article

Epigenetic and Transcriptional Pre-patterning—An Emerging Theme in Cortical Neurogenesis.

scientific article

Epigenome profiling and editing of neocortical progenitor cells during development.

scientific article

Essential role of endophilin A in synaptic vesicle budding at the Drosophila neuromuscular junction

scientific article

Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex.

scientific article published on 21 March 2018

Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells

scientific article published in June 2009

Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex

scientific article published on 02 August 2018

Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex

scientific article published on 19 March 2020

Focus on molecules: prominin-1 (CD133).

scientific article

GEMC1 is a critical regulator of multiciliated cell differentiation

scientific article published on March 2016

Genetic Modification of Brain Organoids

scientific article published on 17 December 2019

H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion

scientific article published on 15 September 2021

Haematopoietic stem cell differentiation promotes the release of prominin‐1/CD133‐containing membrane vesicles—a role of the endocytic–exocytic pathway ⬇️

scientific article published on May 18, 2011

How the extracellular matrix shapes neural development

article

Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals

scientific article published on 9 September 2022

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

scientific article (publication date: 22 December 2015)

Human prominin-1 (CD133) is detected in both neoplastic and non-neoplastic salivary gland diseases and released into saliva in a ubiquitinated form.

scientific article

Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis

scientific article published on 26 December 2019

Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset

scientific article published on 18 June 2020

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion

scientific article

Human-specific genomic signatures of neocortical expansion

scientific article published on 29 November 2016

Human-specific induces hallmarks of neocortical expansion in developing ferret neocortex

scientific article published on 28 November 2018

Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors

scientific article

Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis

scientific journal article

In Vivo Targeting of Neural Progenitor Cells in Ferret Neocortex by In Utero Electroporation

scientific article published on 06 May 2020

Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7.

scientific article published on 19 February 2018

Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex

scientific article published on October 2008

Integrin αvβ3 and thyroid hormones promote expansion of progenitors in embryonic neocortex

scientific article published on February 2014

Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex

scientific article

Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

scientific journal article

Isolation of neural crest derived chromaffin progenitors from adult adrenal medulla

scientific article

Isolation of neural stem cells from the postnatal cerebellum

scientific article published on 22 May 2005

Lipidome of midbody released from neural stem and progenitor cells during mammalian cortical neurogenesis

scientific article

Live imaging at the onset of cortical neurogenesis reveals differential appearance of the neuronal phenotype in apical versus basal progenitor progeny

scientific article (publication date: 2008)

Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development

scientific article published in 2022

Loss of epithelial hypoxia-inducible factor prolyl hydroxylase 2 accelerates skin wound healing in mice

scientific article published on 24 June 2013

Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration

scientific journal article

Making bigger brains-the evolution of neural-progenitor-cell division.

scientific article published on September 2008

Malformations of Human Neocortex in Development - Their Progenitor Cell Basis and Experimental Model Systems

Membrane curvature: a case of endofeelin’…

scientific article published on 01 April 2002

Microinjection of membrane-impermeable molecules into single neural stem cells in brain tissue

scientific article

Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1

scientific journal article

Monoclonal Antibodies 13A4 and AC133 Do Not Recognize the Canine Ortholog of Mouse and Human Stem Cell Antigen Prominin-1 (CD133)

scientific article

Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice

scientific article

Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.

scientific article published in May 2009

Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline

scientific journal article

Myosin II is required for interkinetic nuclear migration of neural progenitors

scientific article published on 09 September 2009

N-cadherin specifies first asymmetry in developing neurons ⬇️

scientific article published on February 21, 2012

Neocortex expansion in development and evolution - from cell biology to single genes

scientific article published on 31 May 2016

Neocortical Expansion Due to Increased Proliferation of Basal Progenitors Is Linked to Changes in Their Morphology

scientific article published on 21 March 2019

Neural progenitor cells and their role in the development and evolutionary expansion of the neocortex

scientific article published on 16 November 2016

Neural progenitor nuclei IN motion

scientific article published on September 2010

Neural progenitors, neurogenesis and the evolution of the neocortex

scientific article published on June 2014

Neural stem and progenitor cells shorten S-phase on commitment to neuron production

scientific article published on January 2011

Neurodevelopmental LincRNA Microsyteny Conservation and Mammalian Brain Size Evolution

scientific article published on 2 July 2015

Neurogenesis during development of the vertebrate central nervous system

scientific article published on 17 March 2014

Neurogenesis in G minor

scientific article

Neuronal and glial cell biology

scientific article published on 01 October 2007

Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis

scientific article

Neurotransmitters as Modulators of Neural Progenitor Cell Proliferation During Mammalian Neocortex Development

scientific article published on 26 May 2020

Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells

scientific article

Nonselective sister chromatid segregation in mouse embryonic neocortical precursor cells

scientific article published on 2 April 2009

Novel gene function and regulation in neocortex expansion

scientific article

Novel insights into mammalian embryonic neural stem cell division: focus on microtubules

scientific article published on December 2015

OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

scientific article published on 2 May 2010

On the origin of neurons

scientific article

Organoid single-cell genomic atlas uncovers human-specific features of brain development

scientific article published on 16 October 2019

Primate neocortex development and evolution: Conserved versus evolved folding

scientific article published on 29 December 2018

Progenitor networking in the fetal primate neocortex

scientific article published on October 2013

Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour.

scientific article

Prominin-1 (CD133) and the Cell Biology of Neural Progenitors and Their Progeny ⬇️

scientific article published on January 1, 2013

Prominin-1 (CD133) is not restricted to stem cells located in the basal compartment of murine and human prostate.

scientific article published on 17 August 2010

Prominin-1 (CD133) modulates the architecture and dynamics of microvilli

scientific article published on 14 November 2018

Prominin-1 controls stem cell activation by orchestrating ciliary dynamics

scientific article published on 06 December 2018

Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer

scientific article published on 19 November 2004

Prominin-1: a distinct cholesterol-binding membrane protein and the organisation of the apical plasma membrane of epithelial cells.

scientific article published on January 2010

Prominin-2 is a cholesterol-binding protein associated with apical and basolateral plasmalemmal protrusions in polarized epithelial cells and released into urine

scientific journal article

Prominin-2 is a novel marker of distal tubules and collecting ducts of the human and murine kidney

scientific article published on 24 March 2010

Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3

scientific article published on 22 March 2020

Protein and lipid sorting from thetrans–Golgi network to secretory granules—recent developments

article

RNA interference in postimplantation mouse embryos

Release of extracellular membrane particles carrying the stem cell marker prominin-1 (CD133) from neural progenitors and other epithelial cells

scientific journal article

Release of extracellular membrane vesicles from microvilli of epithelial cells is enhanced by depleting membrane cholesterol.

scientific article published on 31 January 2009

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

scientific article published on 08 February 2016

Requirement for GTP hydrolysis in the formation of secretory vesicles

scientific article published in Nature

Response to Comment on “Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals”

scientific article published on 29 March 2023

Resurrecting remnants: the lives of post-mitotic midbodies

scientific article published on 11 December 2012

Robotic platform for microinjection into single cells in brain tissue

scientific article published on 30 August 2019

Robust expression of Prominin-2 all along the adult male reproductive system and urinary bladder

scientific article published on 7 June 2008

Role of maternal thyroid hormones in the developing neocortex and during human evolution ⬇️

scientific article published on July 16, 2013

S-phase duration is the main target of cell cycle regulation in neural progenitors of developing ferret neocortex

scientific article published on 10 May 2015

Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain development

scientific article

Signs of Reduced Basal Progenitor Levels and Cortical Neurogenesis in Human Fetuses with Open Spina Bifida at 11-15 Weeks of Gestation

scientific article published on 17 January 2020

Single-cell detection of microRNAs in developing vertebrate embryos after acute administration of a dual-fluorescence reporter/sensor plasmid.

scientific article published in December 2006

Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors

scientific article

Spatial distribution of prominin-1 (CD133)-positive cells within germinative zones of the vertebrate brain

scientific article

Specific polar subpopulations of astral microtubules control spindle orientation and symmetric neural stem cell division

scientific article published on 4 July 2014

Stem cell marker prominin-1/AC133 is expressed in duct cells of the adult human pancreas.

scientific article

Stem cells: slow and steady wins the race

scientific article published in May 2015

Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex

scientific article (publication date: August 2015)

Symmetric versus asymmetric cell division during neurogenesis in the developing vertebrate central nervous system

scientific article

The Golgi Apparatus in Polarized Neuroepithelial Stem Cells and Their Progeny: Canonical and Noncanonical Features

scientific article published on 01 January 2019

The Mode of Stem Cell Division Is Dependent on the Differential Interaction of β-Catenin with the Kat3 Coactivators CBP or p300

scientific article published on 09 July 2019

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

scientific journal article

The cell biology of neural stem and progenitor cells and its significance for their proliferation versus differentiation during mammalian brain development

scientific article

The cell biology of neurogenesis

scientific article

The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex

scientific article published on 27 June 2014

The centrosome protein AKNA regulates neurogenesis via microtubule organization

scientific article published on 20 February 2019

The granin (chromogranin/secretogranin) family

scientific article

The intriguing links between prominin-1 (CD133), cholesterol-based membrane microdomains, remodeling of apical plasma membrane protrusions, extracellular membrane particles, and (neuro)epithelial cell differentiation.

scientific article published on 02 February 2010

The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex

scientific journal article

The role of α-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration

scientific article

The secondary loss of gyrencephaly as an example of evolutionary phenotypical reversal

scientific article (publication date: 2013)

The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia.

scientific article published on 21 July 2008

Tis21 expression marks not only populations of neurogenic precursor cells but also new postmitotic neurons in adult hippocampal neurogenesis

scientific article

Tissue-specific RNA interference in post-implantation mouse embryos using directional electroporation and whole embryo culture

scientific article published on March 2004

Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA

scientific article

Transcriptional Regulators and Human-Specific/Primate-Specific Genes in Neocortical Neurogenesis ⬇️

scientific article published on 29 June 2020

Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal

scientific article

Transport, Metabolism, and Function of Thyroid Hormones in the Developing Mammalian Brain

Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions.

scientific article published on May 2014

Tyrosine O-sulfation.

scientific article published on March 2005

YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex

article published in 2019

miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex

scientific article

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