List of works - Atsushi Natsume

A combination of IFN-beta and temozolomide in human glioma xenograft models: implication of p53-mediated MGMT downregulation

scientific article

A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation

scientific article published on 9 September 2010

A hypoxia-inducible factor (HIF)-3α splicing variant, HIF-3α4 impairs angiogenesis in hypervascular malignant meningiomas with epigenetically silenced HIF-3α4.

scientific article published on 26 February 2013

A novel method of intracranial injection via the postglenoid foramen for brain tumor mouse models

scientific article

A novel monoclonal antibody GMab-m1 specifically recognizes IDH1-R132G mutation.

scientific article published on 26 February 2013

A phase I clinical trial of interferon-beta gene therapy for high-grade glioma: novel findings from gene expression profiling and autopsy

scientific article published on April 2008

Activation of Yes-Associated Protein in Low-Grade Meningiomas Is Regulated by Merlin, Cell Density, and Extracellular Matrix Stiffness

scientific article published on July 2015

Adoptive immunotherapy for the treatment of glioblastoma: progress and possibilities

scientific article published on December 2016

Adoptive transfer of genetically modified Wilms' tumor 1-specific T cells in a novel malignant skull base meningioma model

scientific article

Advanced new neurosurgical procedure using integrated system of intraoperative MRI and neuronavigation with multimodal neuroradiological images.

scientific article published in September 2009

An immuno-wall microdevice exhibits rapid and sensitive detection of IDH1-R132H mutation specific to grade II and III gliomas

scientific article published on 04 October 2016

Anaplastic meningioma with rapid growth after omental flap transposition: a case report and experimental study

scientific article

Antitumorigenic effect of interferon-β by inhibition of undifferentiated glioblastoma cells

scientific article published on 14 September 2015

Applicable advances in the molecular pathology of glioblastoma

scientific article published on 16 June 2015

Assessment of tumor cells in a mouse model of diffuse infiltrative glioma by Raman spectroscopy.

scientific article published on 27 August 2014

Association of dorsal inferior frontooccipital fasciculus fibers in the deep parietal lobe with both reading and writing processes: a brain mapping study

scientific article published on 21 March 2014

BRAIN TUMOR SURGERY NAVIGATION SYSTEM BASED ON UPDATING PREOPERATIVE IMAGES USING POSITIONAL INFORMATION OF SURGICAL TOOLS.

scientific article published in July 2014

Blockade of gap junction hemichannel protects secondary spinal cord injury from activated microglia-mediated glutamate exitoneurotoxicity

scientific article

CAR T Cells Targeting Podoplanin Reduce Orthotopic Glioblastomas in Mouse Brains

scientific article

Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma

scientific article published on 29 May 2013

Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells

scientific article

Correlation between quantified promoter methylation and enzymatic activity of O6-methylguanine-DNA methyltransferase in glioblastomas

scientific article published on 26 January 2012

Current trends in targeted therapies for glioblastoma multiforme

scientific article published on 5 March 2012

Cytokine Therapy of Gliomas.

scientific article

Cytokine networks in glioma

scientific article published on 09 June 2011

EGFR mutations in patients with brain metastases from lung cancer: association with the efficacy of gefitinib.

scientific article published on 20 January 2006

Effectiveness of plasma treatment on gastric cancer cells.

scientific article

Epigenetic aberrations and therapeutic implications in gliomas

scientific article published on 15 March 2010

Epigenetic dysregulation in glioma.

scientific article published on April 2014

Epigenetic subclassification of meningiomas based on genome-wide DNA methylation analyses

scientific article

Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts

scientific article

GENO-03PROGNOSTIC SIGNIFICANCE OF GENETIC ALTERATIONS FROM COMPREHENSIVE ANALYSIS IN LOWER-GRADE GLIOMAS.

scientific article

Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase

scientific article published on 4 May 2015

Gene therapy for high-grade glioma

scientific article published on January 2010

Gene therapy for high-grade glioma: current approaches and future directions

scientific article published on 13 July 2008

Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone

scientific article published on 04 May 2020

Genetically heterogeneous glioblastoma recurring with disappearance of 1p/19q losses: case report

scientific article

Glioma-initiating cells and molecular pathology: implications for therapy

scientific article published on 28 January 2011

Inhibition of Acid Secretion in Gastric Parietal Cells by the Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitor KN-93 ⬇️

scientific article published on September 15, 1993

Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma

scientific article published in July 2009

Interferon-β delivery via human neural stem cell abates glial scar formation in spinal cord injury

scientific article

JCOG0911 INTEGRA study: a randomized screening phase II trial of interferonβ plus temozolomide in comparison with temozolomide alone for newly diagnosed glioblastoma.

scientific article

Lack of GD3 synthase (St8sia1) attenuates malignant properties of gliomas in genetically engineered mouse model

scientific article published on 30 June 2021

Lack of presence of the human cytomegalovirus in human glioblastoma.

scientific article published on 13 December 2013

Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide, ifosfamide and carboplatin chemotherapy and whole-brain radiation therapy

scientific article published on 12 July 2011

Mutational landscape and clonal architecture in grade II and III gliomas

scientific article published on 13 April 2015

Novel somatic and germline mutations in intracranial germ cell tumours.

scientific article

Paired related homeobox 1 is associated with the invasive properties of glioblastoma cells

scientific article published on 18 December 2014

Papillary glioneuronal tumor with a high proliferative component and minigemistocytes in a child

scientific article

Peptide-based inhibition of the HOXA9/PBX interaction retards the growth of human meningioma.

scientific article published on 20 October 2013

Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor α2 chain in recurrent malignant glioma patients with HLA-A24/A02 allele.

scientific article

Podoplanin - an emerging cancer biomarker and therapeutic target.

scientific article published on 25 March 2018

Preclinical evaluation of an O(6)-methylguanine-DNA methyltransferase-siRNA/liposome complex administered by convection-enhanced delivery to rat and porcine brains

scientific article published on 15 January 2014

Progressively unstable c2 spondylolysis requiring spinal fusion: case report

scientific article

Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation

scientific article published on 5 March 2014

Retrovirally engineered T-cell-based immunotherapy targeting type III variant epidermal growth factor receptor, a glioma-associated antigen

scientific article published on 30 September 2010

Rhabdoid glioblastoma in a child: case report and literature review

scientific article published on 07 January 2011

Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells

scientific article

Surgical benefits of combined awake craniotomy and intraoperative magnetic resonance imaging for gliomas associated with eloquent areas

scientific article published on 6 January 2017

Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment

scientific article published on 06 December 2016

The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma

scientific article (publication date: 2011)

The modulation of microRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma

scientific article

List of works by Atsushi Natsume

A combination of IFN-beta and temozolomide in human glioma xenograft models: implication of p53-mediated MGMT downregulation

A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation

A hypoxia-inducible factor (HIF)-3α splicing variant, HIF-3α4 impairs angiogenesis in hypervascular malignant meningiomas with epigenetically silenced HIF-3α4.

A novel method of intracranial injection via the postglenoid foramen for brain tumor mouse models

A novel monoclonal antibody GMab-m1 specifically recognizes IDH1-R132G mutation.

A phase I clinical trial of interferon-beta gene therapy for high-grade glioma: novel findings from gene expression profiling and autopsy

Activation of Yes-Associated Protein in Low-Grade Meningiomas Is Regulated by Merlin, Cell Density, and Extracellular Matrix Stiffness

Adoptive immunotherapy for the treatment of glioblastoma: progress and possibilities

Adoptive transfer of genetically modified Wilms' tumor 1-specific T cells in a novel malignant skull base meningioma model

Advanced new neurosurgical procedure using integrated system of intraoperative MRI and neuronavigation with multimodal neuroradiological images.

An immuno-wall microdevice exhibits rapid and sensitive detection of IDH1-R132H mutation specific to grade II and III gliomas

Anaplastic meningioma with rapid growth after omental flap transposition: a case report and experimental study

Antitumorigenic effect of interferon-β by inhibition of undifferentiated glioblastoma cells

Applicable advances in the molecular pathology of glioblastoma

Assessment of tumor cells in a mouse model of diffuse infiltrative glioma by Raman spectroscopy.

Association of dorsal inferior frontooccipital fasciculus fibers in the deep parietal lobe with both reading and writing processes: a brain mapping study

BRAIN TUMOR SURGERY NAVIGATION SYSTEM BASED ON UPDATING PREOPERATIVE IMAGES USING POSITIONAL INFORMATION OF SURGICAL TOOLS.

Blockade of gap junction hemichannel protects secondary spinal cord injury from activated microglia-mediated glutamate exitoneurotoxicity

CAR T Cells Targeting Podoplanin Reduce Orthotopic Glioblastomas in Mouse Brains

Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma

Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells

Correlation between quantified promoter methylation and enzymatic activity of O6-methylguanine-DNA methyltransferase in glioblastomas

Current trends in targeted therapies for glioblastoma multiforme

Cytokine Therapy of Gliomas.

Cytokine networks in glioma

EGFR mutations in patients with brain metastases from lung cancer: association with the efficacy of gefitinib.

Effectiveness of plasma treatment on gastric cancer cells.

Epigenetic aberrations and therapeutic implications in gliomas

Epigenetic dysregulation in glioma.

Epigenetic subclassification of meningiomas based on genome-wide DNA methylation analyses

Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts

GENO-03PROGNOSTIC SIGNIFICANCE OF GENETIC ALTERATIONS FROM COMPREHENSIVE ANALYSIS IN LOWER-GRADE GLIOMAS.

Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase

Gene therapy for high-grade glioma

Gene therapy for high-grade glioma: current approaches and future directions

Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone

Genetically heterogeneous glioblastoma recurring with disappearance of 1p/19q losses: case report

Glioma-initiating cells and molecular pathology: implications for therapy

Inhibition of Acid Secretion in Gastric Parietal Cells by the Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitor KN-93 ⬇️

Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma

Interferon-β delivery via human neural stem cell abates glial scar formation in spinal cord injury

JCOG0911 INTEGRA study: a randomized screening phase II trial of interferonβ plus temozolomide in comparison with temozolomide alone for newly diagnosed glioblastoma.

Lack of GD3 synthase (St8sia1) attenuates malignant properties of gliomas in genetically engineered mouse model

Lack of presence of the human cytomegalovirus in human glioblastoma.

Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide, ifosfamide and carboplatin chemotherapy and whole-brain radiation therapy

Mutational landscape and clonal architecture in grade II and III gliomas

Novel somatic and germline mutations in intracranial germ cell tumours.

Paired related homeobox 1 is associated with the invasive properties of glioblastoma cells

Papillary glioneuronal tumor with a high proliferative component and minigemistocytes in a child

Peptide-based inhibition of the HOXA9/PBX interaction retards the growth of human meningioma.

Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor α2 chain in recurrent malignant glioma patients with HLA-A*24/A*02 allele.

Podoplanin - an emerging cancer biomarker and therapeutic target.

Preclinical evaluation of an O(6)-methylguanine-DNA methyltransferase-siRNA/liposome complex administered by convection-enhanced delivery to rat and porcine brains

Progressively unstable c2 spondylolysis requiring spinal fusion: case report

Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation

Retrovirally engineered T-cell-based immunotherapy targeting type III variant epidermal growth factor receptor, a glioma-associated antigen

Rhabdoid glioblastoma in a child: case report and literature review

Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells

Surgical benefits of combined awake craniotomy and intraoperative magnetic resonance imaging for gliomas associated with eloquent areas

Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment

The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma

The modulation of microRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma

Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor α2 chain in recurrent malignant glioma patients with HLA-A24/A02 allele.