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List of works by B Kim Lee Sim

A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1

scientific article published on 01 May 2020

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

scientific article published on 19 March 2018

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.

scientific article

Activation of TCR Vδ1+ and Vδ1-Vδ2- γδ T Cells upon Controlled Infection with Plasmodium falciparum in Tanzanian Volunteers

scientific article published on 04 December 2019

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope

scientific article published in Science

Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection

scientific article published on 21 February 2017

Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

scientific article published on 01 January 2019

Beyond Blood Smears: Qualification of Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections.

scientific article published in June 2019

Clonal selection drives protective memory B cell responses in controlled human malaria infection

scientific article published in February 2018

Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites

scientific article

Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression

scientific article published on 11 July 2019

Corrigendum: Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

scientific article published in June 2016

Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria

scientific article

Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice

scientific article published on 9 October 2017

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe

scientific article

Optimizing Intradermal Administration of Cryopreserved Plasmodium falciparum Sporozoites in Controlled Human Malaria Infection

scientific article

Plasmodium falciparum malaria challenge by the bite of aseptic Anopheles stephensi mosquitoes: results of a randomized infectivity trial

scientific article (publication date: 21 October 2010)

Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines

scientific article published on 12 October 2015

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

scientific article (publication date: 9 May 2016)

Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial.

scientific article

Successful human infection with P. falciparum using three aseptic Anopheles stephensi mosquitoes: a new model for controlled human malaria infection

scientific article

Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes

scientific article (publication date: May 2014)

γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations.

scientific article published on 27 October 2017

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