List of works by Bruno P A Cammue

2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents.

scientific article

A Linear 19-Mer Plant Defensin-Derived Peptide Acts Synergistically with Caspofungin against Candida albicans Biofilms

scientific article published on 20 October 2017

A fungicidal piperazine-1-carboxamidine induces mitochondrial fission-dependent apoptosis in yeast

scientific article published on 18 August 2010

A putative novel role for plant defensins: a defensin from the zinc hyper-accumulating plant, Arabidopsis halleri, confers zinc tolerance

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A set of modular plant transformation vectors allowing flexible insertion of up to six expression units

scientific article published on 01 September 2002

ARA-PEPs: a repository of putative sORF-encoded peptides in Arabidopsis thaliana.

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ARACINs, Brassicaceae-specific peptides exhibiting antifungal activities against necrotrophic pathogens in Arabidopsis

scientific article published on 15 January 2015

Affinity comparison of p3 and p8 peptide displaying bacteriophages using surface plasmon resonance

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Alternating Current Electrophoretic Deposition for the Immobilization of Antimicrobial Agents on Titanium Implant Surfaces.

scientific article published on 17 February 2017

An antibiofilm coating of 5-aryl-2-aminoimidazole covalently attached to a titanium surface

scientific article published on 13 December 2018

Analysis of network architecture reveals phylogenetic constraints on mycorrhizal specificity in the genus Orchis (Orchidaceae)

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Antibacterial activity of a new broad-spectrum antibiotic covalently bound to titanium surfaces.

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Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation.

scientific article published on 27 May 2011

Antifungal activity in plants from Chinese traditional and folk medicine

scientific article published on 31 July 2012

Antifungal activity of synthetic peptides derived from Impatiens balsamina antimicrobial peptides Ib-AMP1 and Ib-AMP4.

scientific article published on 16 February 2005

Antifungal carbazoles.

scientific article published on January 2009

Antifungal plant defensins: mechanisms of action and production

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Antimicrobial Peptides as a Strategy to Combat Fungal Biofilms

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Apoptosis-inducing antifungal peptides and proteins.

scientific article published on October 2011

Arabidopsis thaliana plant defensin AtPDF1.1 is involved in the plant response to biotic stress

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Arabidopsis thaliana plants expressing human beta-defensin-2 are more resistant to fungal attack: functional homology between plant and human defensins

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Artemisinins, new miconazole potentiators resulting in increased activity against Candida albicans biofilms.

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Assessment of RNAi-induced silencing in banana (Musa spp.).

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Azoles: Mode of Antifungal Action and Resistance Development. Effect of Miconazole on Endogenous Reactive Oxygen Species Production in Candida albicans

Ceramide involvement in apoptosis and apoptotic diseases.

scientific article published on June 2006

Combination Therapy to Treat Fungal Biofilm-Based Infections

scientific article published on 23 November 2020

Combination of miconazole and domiphen bromide is fungicidal against biofilms of resistant Candida spp

scientific article published on 20 July 2020

Combinatorial drug approaches to tackle Candida albicans biofilms

scientific article published on 12 June 2015

Combining Biocontrol Agents with Chemical Fungicides for Integrated Plant Fungal Disease Control

scientific article published on 04 December 2020

Controlled release of chlorhexidine antiseptic from microporous amorphous silica applied in open porosity of an implant surface

scientific article published on 20 July 2011

Covalent immobilization of antimicrobial agents on titanium prevents Staphylococcus aureus and Candida albicans colonization and biofilm formation.

scientific article published on 24 December 2015

Currently used antimycotics: spectrum, mode of action and resistance occurrence.

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Defensins from insects and plants interact with fungal glucosylceramides

scientific article published on 6 November 2003

Derivatives of the mouse cathelicidin-related antimicrobial peptide (CRAMP) inhibit fungal and bacterial biofilm formation

scientific article published on 30 June 2014

Design and development of a DNA array for rapid detection and identification of multiple tomato vascular wilt pathogens

scientific article

Detecting single nucleotide polymorphisms using DNA arrays for plant pathogen diagnosis

scientific article published on 01 February 2006

Dietary intervention, but not losartan, completely reverses non-alcoholic steatohepatitis in obese and insulin resistant mice.

scientific article published on 23 February 2017

DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckii), interacts with sphingolipids from Saccharomyces cerevisiae

scientific article published in September 2003

Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa

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Enhanced resistance to early blight in transgenic tomato lines expressing heterologous plant defense genes.

scientific article published on 27 July 2005

Esa1, an Arabidopsis mutant with enhanced susceptibility to a range of necrotrophic fungal pathogens, shows a distorted induction of defense responses by reactive oxygen generating compounds

scientific article published in January 2002

Evaluation of the toxicity of 5-aryl-2-aminoimidazole-based biofilm inhibitors against eukaryotic cell lines, bone cells and the nematode Caenorhabditis elegans.

scientific article

Expanding the pharmacological profile of κ-hefutoxin 1 and analogues: A focus on the inhibitory effect on the oncogenic channel Kv10.1.

scientific article published on 28 August 2016

From extensive clone libraries to comprehensive DNA arrays for the efficient and simultaneous detection and identification of orchid mycorrhizal fungi

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Fungal Glucosylceramide-Specific Camelid Single Domain Antibodies Are Characterized by Broad Spectrum Antifungal Activity.

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Fungal β-1,3-glucan increases ofloxacin tolerance of Escherichia coli in a polymicrobial E. coli/Candida albicans biofilm.

scientific article published on 9 March 2015

Fungicidal activity of truncated analogues of dihydrosphingosine

scientific article published on 20 May 2008

Genome-Wide Characterization of ISR Induced in Arabidopsis thaliana by Trichoderma hamatum T382 Against Botrytis cinerea Infection.

scientific article published on 29 May 2012

Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

scientific article published on 8 August 2016

Hub Protein Controversy: Taking a Closer Look at Plant Stress Response Hubs.

scientific article published on 5 June 2018

IPT1-independent sphingolipid biosynthesis and yeast inhibition by syringomycin E and plant defensin DmAMP1.

scientific article

Identification of fungicidal 2,6-disubstituted quinolines with activity against Candida biofilms

scientific article published on 18 October 2012

Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells

scientific article published in August 2016

Implant functionalization with mesoporous silica: A promising antibac terial strategy, but does such an implant osseointegrate?

scientific article published on 31 December 2020

In vitro activity of the antiasthmatic drug zafirlukast against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans

scientific article published on 12 January 2017

In vitro activity of the antifungal plant defensin RsAFP2 against Candida isolates and its in vivo efficacy in prophylactic murine models of candidiasis

scientific article published on 29 September 2008

Increasing the Fungicidal Action of Amphotericin B by Inhibiting the Nitric Oxide-Dependent Tolerance Pathway.

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Interactions of antifungal plant defensins with fungal membrane components.

scientific article published on November 2003

Isolation and characterization of Neurospora crassa mutants resistant to antifungal plant defensins

scientific article published in November 2003

Joined in death: highlights of the Sixth International Meeting on Yeast Apoptosis in Leuven, Belgium, 30 April-4 May 2008.

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Level of M(IP)2C sphingolipid affects plant defensin sensitivity, oxidative stress resistance and chronological life-span in yeast

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Low specificity and nested subset structure characterize mycorrhizal associations in five closely related species of the genus Orchis

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Membrane rafts are involved in intracellular miconazole accumulation in yeast cells.

scientific article published on 25 September 2009

Miconazole Induces Changes in Actin Cytoskeleton prior to Reactive Oxygen Species Induction in Yeast

scientific article published in Journal of Biological Chemistry

Mining the genome of Arabidopsis thaliana as a basis for the identification of novel bioactive peptides involved in oxidative stress tolerance

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Mitochondrial dysfunction leads to reduced chronological lifespan and increased apoptosis in yeast

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Mode of action of plant defensins suggests therapeutic potential

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Modulation of the Substitution Pattern of 5-Aryl-2-Aminoimidazoles Allows Fine-Tuning of Their Antibiofilm Activity Spectrum and Toxicity.

scientific article published on 22 August 2016

Mycorrhizal associations and reproductive isolation in three closely related Orchis species

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Neutral glycolipids of the filamentous fungus Neurospora crassa: altered expression in plant defensin-resistant mutants

scientific article published on 16 January 2005

Novel anti-infective implant substrates: controlled release of antibiofilm compounds from mesoporous silica-containing macroporous titanium

scientific article published on 7 January 2015

Novel fungicidal benzylsulfanyl-phenylguanidines

scientific article published on 24 April 2011

Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo

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Pathogen-responsive expression of a putative ATP-binding cassette transporter gene conferring resistance to the diterpenoid sclareol is regulated by multiple defense signaling pathways in Arabidopsis.

scientific article published on 2 October 2003

Phytosphingosine-1-phosphate is a signaling molecule involved in miconazole resistance in sessile Candida albicans cells

scientific article published on 21 February 2012

Plant defensins.

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Plant pathogenesis-related (PR) proteins: a focus on PR peptides.

scientific article published on 26 June 2008

Plant-derived decapeptide OSIP108 interferes with Candida albicans biofilm formation without affecting cell viability

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Potentiation of antibiofilm activity of amphotericin B by superoxide dismutase inhibition

scientific article published on September 2013

Protocol for Determination of the Persister Subpopulation in Candida Albicans Biofilms

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Quantification of disease progression of several microbial pathogens on Arabidopsis thaliana using real-time fluorescence PCR.

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Quantitative assessment of phytopathogenic fungi in various substrates using a DNA macroarray.

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RNAseq-based transcriptome analysis of Lactuca sativa infected by the fungal necrotroph Botrytis cinerea

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Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms

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Repurposing AM404 for the treatment of oral infections by Porphyromonas gingivalis.

scientific article published on 7 April 2017

Repurposing Toremifene for Treatment of Oral Bacterial Infections.

scientific article published on 19 December 2016

Repurposing as a means to increase the activity of amphotericin B and caspofungin against Candida albicans biofilms.

scientific article

Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth

scientific article published on 17 November 2020

Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis.

scientific article published on 10 June 2014

SKN1, a novel plant defensin-sensitivity gene in Saccharomyces cerevisiae, is implicated in sphingolipid biosynthesis

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Skn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae

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Sphingolipids and mitochondrial function in budding yeast

scientific article published on 25 June 2014

Stable high-level transgene expression inArabidopsis thalianausing gene silencing mutants and matrix attachment regions

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Stimulation of superoxide production increases fungicidal action of miconazole against Candida albicans biofilms

scientific article published on 07 June 2016

Structure-activity relationship study of the antimicrobial CRAMP-derived peptide CRAMP20-33

scientific article published on 31 August 2018

Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation.

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Superoxide dismutases are involved in Candida albicans biofilm persistence against miconazole

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Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures

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Synergistic activity of the tyrocidines, antimicrobial cyclodecapeptides from Bacillus aneurinolyticus, with amphotericin B and caspofungin against Candida albicans biofilms

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Synthesis and fungicidal activity of 3,5-dichloropyrazin-2(1H)-one derivatives.

scientific article published on 13 June 2009

TEMPORARY REMOVAL: The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast

scientific article published on 05 March 2020

The Antifungal Activity of RsAFP2, a Plant Defensin from Raphanus sativus , Involves the Induction of Reactive Oxygen Species in Candida albicans

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The Antifungal Plant Defensin HsAFP1 Is a Phosphatidic Acid-Interacting Peptide Inducing Membrane Permeabilization.

scientific article published on 21 November 2017

The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans

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The Arabidopsis mutant iop1 exhibits induced over-expression of the plant defensin gene PDF1.2 and enhanced pathogen resistance

scientific article published on November 2003

The Arabidopsis thaliana RNA editing factor SLO2, which affects the mitochondrial electron transport chain, participates in multiple stress and hormone responses.

scientific article published on 29 August 2013

The Nonsteroidal Antiinflammatory Drug Diclofenac Potentiates the In Vivo Activity of Caspofungin Against Candida albicans Biofilms

scientific article published on 14 September 2012

The Plant Peptidome: An Expanding Repertoire of Structural Features and Biological Functions

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The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels.

scientific article published on 30 August 2016

The antifungal plant defensin RsAFP2 from radish induces apoptosis in a metacaspase independent way in Candida albicans.

scientific article published on 14 July 2009

The heat-induced molecular disaggregase Hsp104 of Candida albicans plays a role in biofilm formation and pathogenicity in a worm infection model

scientific article published on 25 May 2012

The influence of matrix attachment regions on transgene expression in Arabidopsis thaliana wild type and gene silencing mutants

scientific article published on March 2007

The plant decapeptide OSIP108 can alleviate mitochondrial dysfunction induced by cisplatin in human cells.

scientific article published on 19 September 2014

The plant decapeptide OSIP108 prevents copper-induced apoptosis in yeast and human cells

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The plant decapeptide OSIP108 prevents copper-induced toxicity in various models for Wilson disease

scientific article published on 16 August 2014

The plant defensin RsAFP2 induces cell wall stress, septin mislocalization and accumulation of ceramides in Candida albicans.

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The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.

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The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms

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The role of ethylene in host-pathogen interactions

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The toolbox of Trichoderma spp. in the biocontrol of Botrytis cinerea disease

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Therapeutic potential of antifungal plant and insect defensins

scientific article published on 04 September 2007

Transcription factor Efg1 contributes to the tolerance of Candida albicans biofilms against antifungal agents in vitro and in vivo

scientific article published on 15 March 2012

Transgenic expression in Arabidopsis of a polyprotein construct leading to production of two different antimicrobial proteins

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Transgenic rose lines harboring an antimicrobial protein gene, Ace-AMP1 , demonstrate enhanced resistance to powdery mildew ( Sphaerotheca pannosa )

scientific article published on September 24, 2003

Transient gene expression in transformed banana (Musa cv. Bluggoe) protoplasts and embryogenic cell suspensions

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Tuning the Surface Interactions between Single Cells and an OSTE+ Microwell Array for Enhanced Single Cell Manipulation

scientific article published on 07 January 2021

Ultraviolet-B radiation stimulates downward leaf curling in Arabidopsis thaliana

scientific article published on 17 December 2014

Use of a PTGS-MAR expression system for efficient in planta production of bioactive Arabidopsis thaliana plant defensins

scientific article published on 19 December 2006

What lies beneath: belowground defense strategies in plants

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Yeast as a model for the identification of novel survival-promoting compounds applicable to treat degenerative diseases

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