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List of works by Erika Holzbaur

A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity

scientific article published on 7 March 2018

A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity

scientific article

A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation

scientific article

A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration

scientific article published in August 2009

A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner

scientific article published on 10 November 2020

Actin cables and comet tails organize mitochondrial networks in mitosis

scientific article published on 03 March 2021

Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B.

scientific article published in November 2016

Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons.

scientific article published on 6 March 2017

Angular measurements of the dynein ring reveal a stepping mechanism dependent on a flexible stalk

scientific article published on 22 May 2017

Autophagosome assembly and cargo capture in the distal axon ⬇️

scientific article published on May 1, 2012

Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway

scientific article

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons ⬇️

scientific article published on February 13, 2012

Autophagy and mitophagy in ALS

scientific article published on 05 July 2018

Autophagy in Neurons

scientific article published on 23 July 2019

Axonal autophagy: Mini-review for autophagy in the CNS

scientific article published on 13 March 2018

Axonal transport: Driving synaptic function

scientific article published on 01 October 2019

Axonal transport: cargo-specific mechanisms of motility and regulation

scientific article

CDK5-dependent activation of dynein in the axon initial segment regulates polarized cargo transport in neurons

scientific article published on 23 September 2017

Compartment-Specific Regulation of Autophagy in Primary Neurons

scientific article published on June 2016

Coordination of molecular motors: from in vitro assays to intracellular dynamics

scientific article

Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons

scientific article published on 14 January 2020

Differential regulation of dynein and kinesin motor proteins by tau

scientific journal article

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration

scientific article published in May 2002

Distal spinal and bulbar muscular atrophy caused by dynactin mutation.

scientific article

Dynactin Is Required for Transport Initiation from the Distal Axon ⬇️

scientific article published on April 26, 2012

Dynactin functions as both a dynamic tether and brake during dynein-driven motility.

scientific article published on 4 September 2014

Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor

scientific journal article

Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons

scientific article published on 29 October 2018

Dynein activators and adaptors at a glance

scientific article published on 15 March 2019

Dynein at odd angles?

scientific article published on 21 November 2010

Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes

scientific article published on 18 July 2017

Dynein interacts with the neural cell adhesion molecule (NCAM180) to tether dynamic microtubules and maintain synaptic density in cortical neurons.

scientific article published on 19 August 2013

Dynein tethers and stabilizes dynamic microtubule plus ends

scientific article

Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions

scientific article

Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons

scientific article published on 16 July 2019

Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors ⬇️

scientific article published on October 22, 2012

Force-dependent detachment of kinesin-2 biases track switching at cytoskeletal filament intersections.

scientific article

Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction

scientific article published on 30 June 2016

Huntingtin Fibrils Poke Membranes

scientific article published on September 2017

Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes

scientific article

Intracellular transport: new tools provide insights into multi-motor transport

scientific article published on 01 December 2012

Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse

scientific article published on 03 January 2019

LC3 binding to the scaffolding protein JIP1 regulates processive dynein-driven transport of autophagosomes

scientific article

Lipid Rafts Assemble Dynein Ensembles.

scientific article published on 06 April 2016

Live-cell imaging of retrograde transport initiation in primary neurons.

scientific article published on 2 September 2015

Local Cytoskeletal and Organelle Interactions Impact Molecular-Motor-Driven Early Endosomal Trafficking ⬇️

scientific article published on June 13, 2013

Lysosomal degradation of depolarized mitochondria is rate-limiting in OPTN-dependent neuronal mitophagy

scientific article published on 04 March 2020

Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin

scientific article published on 25 March 2008

Microtubule binding proteins CLIP-170, EB1, and p150Glued form distinct plus-end complexes

scientific article

Microtubule plus-end tracking by CLIP-170 requires EB1.

scientific article

Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly

scientific article published on 5 June 2007

Mitochondrial-cytoskeletal interactions: dynamic associations that facilitate network function and remodeling

scientific article published on 07 April 2018

Motor coordination via a tug-of-war mechanism drives bidirectional vesicle transport.

scientific article published on 15 April 2010

Motor number controls cargo switching at actin-microtubule intersections in vitro

scientific article

Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons.

scientific article

Mutant dynactin in motor neuron disease

scientific article published on 10 March 2003

Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons

article

Myosin learns to recruit AMPA receptors

scientific article published on 01 October 2008

Neuroligin 1 is dynamically exchanged at postsynaptic sites.

scientific article

Neuronal autophagy declines substantially with age and is rescued by overexpression of WIPI2

scientific article published on 03 December 2019

Optogenetic control of organelle transport using a photocaged chemical inducer of dimerization.

scientific article published on May 2015

Ordered Recruitment of Dynactin to the Microtubule Plus-End is Required for Efficient Initiation of Retrograde Axonal Transport ⬇️

scientific article published on August 7, 2013

PLAC-24 is a cytoplasmic dynein-binding protein that is recruited to sites of cell-cell contact

scientific article

Quality Control in Neurons: Mitophagy and Other Selective Autophagy Mechanisms ⬇️

scientific article published on 08 July 2019

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors

scientific article published in 2024

Reconstituting the motility of isolated intracellular cargoes

scientific article published on 01 January 2014

Recruitment of dynein to the Jurkat immunological synapse

scientific article published on 21 September 2006

Regulation of dynactin through the differential expression of p150Glued isoforms

scientific article

Retrograde axonal transport: pathways to cell death?

scientific article

SnapShot: axonal transport

scientific article published on 01 May 2012

Special delivery: dynamic targeting via cortical capture of microtubules

scientific article published in March 2007

Synaptic Vesicle Distribution by Conveyor Belt ⬇️

scientific article published on 01 March 2012

TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation

scientific article

TUBB4A mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model

scientific article published on 28 May 2020

The ADP/ATP translocase drives mitophagy independent of nucleotide exchange

scientific article published on 16 October 2019

The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1.

scientific article published on 18 May 2016

The Kinesin KIF21B Regulates Microtubule Dynamics and Is Essential for Neuronal Morphology, Synapse Function, and Learning and Memory

scientific article published on 21 April 2016

The adaptor proteins HAP1a and GRIP1 collaborate to activate the kinesin-1 isoform KIF5C

scientific article published on 13 December 2019

The impact of cytoskeletal organization on the local regulation of neuronal transport.

scientific article published on 31 August 2017

The interaction of neurofilaments with the microtubule motor cytoplasmic dynein.

scientific article published on September 2004

The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization

scientific article

ToolBox: Live Imaging of intracellular organelle transport in induced pluripotent stem cell-derived neurons

scientific article published on 15 November 2019

Trim58 degrades Dynein and regulates terminal erythropoiesis

scientific article published on 18 September 2014

WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism

scientific article

What Doesn't Kill You Makes You Stronger

scientific article published on 01 November 2018

α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons

scientific article

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