List of works - Luhua Lai

A combined computational and experimental strategy identifies mutations conferring resistance to drugs targeting the BCR-ABL fusion protein

scientific article published on 09 January 2020

A novel allosteric inhibitor that prevents IKKβ activation

scientific article published on 09 January 2018

An autoimmune disease variant of IgG1 modulates B cell activation and differentiation

scientific article published in Science

Arabidopsis pollen tube integrity and sperm release are regulated by RALF-mediated signaling.

scientific article

Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals

scientific article published on 01 May 2020

Computational Multitarget Drug Design.

scientific article published on 6 February 2017

Deep Learning Based Regression and Multiclass Models for Acute Oral Toxicity Prediction with Automatic Chemical Feature Extraction.

scientific article published on 11 October 2017

Discovery of a New Chemoeffector for <i>Escherichia coli</i> Chemoreceptor Tsr and Identification of a Molecular Mechanism of Repellent Sensing

scientific article published in 2022

Efficient ligand discovery from natural herbs by integrating virtual screening, affinity mass spectrometry and targeted metabolomics

scientific article published on 21 February 2019

Identification of Cancer-associated metabolic vulnerabilities by modeling multi-objective optimality in metabolism

scientific article published on 10 October 2019

Integrative structural modeling of a multidomain polo-like kinase

scientific article published on 25 November 2020

Legionella effector SetA as a general O-glucosyltransferase for eukaryotic proteins

scientific article published on 07 January 2019

Mechanism of DNA-Induced Phase Separation for Transcriptional Repressor VRN1

scientific article published on 12 March 2019

Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4.

scientific article published on 24 April 2018

Prediction of Human Cytochrome P450 Inhibition Using a Multitask Deep Autoencoder Neural Network

scientific article published on 30 May 2018

Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro

scientific article published on 12 April 2020

Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism

scientific article published in Nature Communications

Statistical Analysis and Prediction of Covalent Ligand Targeted Cysteine Residues.