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List of works by Hiromu Suzuki

A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors.

scientific article published on 27 July 2015

A genomic screen for long noncoding RNA genes epigenetically silenced by aberrant DNA methylation in colorectal cancer

scientific article published on 24 May 2016

A novel correlation between LINE-1 hypomethylation and the malignancy of gastrointestinal stromal tumors

scientific article published on 26 October 2010

A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth

scientific article published on 23 June 2009

A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells

scientific article

A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells.

scientific article

AKR1B10, a transcriptional target of p53, is downregulated in colorectal cancers associated with poor prognosis.

scientific article published on 18 October 2013

Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer.

scientific article published on February 2005

Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer.

scientific article

Aggressive variant of splenic marginal zone lymphoma characterized using a cancer panel test and treated with rituximab-containing chemotherapy: A case report

scientific article published on 01 August 2020

Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer

scientific article

Analysis of the molecular features of rectal carcinoid tumors to identify new biomarkers that predict biological malignancy

scientific article

Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells

scientific article

Association between genomic alterations and metastatic behavior of colorectal cancer identified by array-based comparative genomic hybridization.

scientific article

Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis.

scientific article published on March 2015

Association of MicroRNA-31-5p with Clinical Efficacy of Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer

scientific article

Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway.

scientific article published on 15 November 2013

Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids.

scientific article published on March 2013

Cancer epigenomics: implications of DNA methylation in personalized cancer therapy

scientific article published on 19 February 2009

Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.

scientific article

Comparative genome analysis identifies the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation.

scientific article published on May 2006

Correction: Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma

scientific article

Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer

scientific article published on 29 February 2008

DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes

scientific article published on 14 October 2021

DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer

scientific article

DNA methylation and cancer pathways in gastrointestinal tumors

scientific article published on December 2008

DNA methylation changes in gastrointestinal disease.

scientific article

DNA methyltransferase 1 is essential for initiation of the colon cancers

scientific article

Downregulation of miR-186 is associated with metastatic recurrence of gastrointestinal stromal tumors

scientific article published on 8 September 2017

Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis

scientific article published on 12 January 2021

Epigenetic alteration of DNA in mucosal wash fluid predicts invasiveness of colorectal tumors.

scientific article published in May 2011

Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer

scientific article (publication date: 15 December 2003)

Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.

scientific article

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

scientific article

Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma.

scientific article

Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis

scientific article published on 11 February 2011

Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-gamma-induced HLA-DR expression in colorectal and gastric cancer cells.

scientific article

Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors.

scientific article published on 17 August 2015

Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer

scientific article published on 20 February 2017

Epigenetic silencing of miR-200b is associated with cisplatin resistance in bladder cancer.

scientific article

Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.

scientific article

Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma

scientific article

Gene amplification and overexpression of PRDM14 in breast cancers.

scientific article

Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus

scientific article published in April 2006

Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma.

scientific article

Genome-wide analysis of mRNA and microRNA expression in colorectal cancer and adjacent normal mucosa

scientific article published on 14 March 2022

Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer.

scientific article

Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.

scientific article

Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.

scientific article published on 27 October 2009

Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma.

scientific article

HER2 expression and PI3K-Akt pathway alterations in gastric cancer.

scientific article published on 20 January 2014

IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.

scientific article

Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites.

scientific article published on 8 January 2014

Identification and characterization of a metastatic suppressor BRMS1L as a target gene of p53.

scientific article published on 13 October 2017

Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer.

scientific article

Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumors

scientific article (publication date: 18 April 2002)

Integrated genetic and epigenetic analysis of cancer-related genes in non-ampullary duodenal adenomas and intramucosal adenocarcinomas

scientific article published on 08 August 2020

Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer.

scientific article published on June 2012

LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis.

scientific article

Methylation of a Panel of MicroRNA Genes Is a Novel Biomarker for Detection of Bladder Cancer ⬇️

scientific article published on November 23, 2012

Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect

scientific article published on 5 October 2010

MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions.

scientific article published on 30 April 2014

Molecular analysis of gastrointestinal tumor and translational research.

scientific article published on January 2011

Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers

scientific article published on 12 December 2017

PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer.

scientific article published on August 2007

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress.

scientific article published on 13 July 2016

Screening for long noncoding RNAs associated with oral squamous cell carcinoma reveals the potentially oncogenic actions of DLEU1

scientific article published on 01 August 2018

Significance of gene mutations in the Wnt signaling pathway in traditional serrated adenomas of the colon and rectum

scientific article published on 24 February 2020

Small interfering RNA-induced CHFR silencing sensitizes oral squamous cell cancer cells to microtubule inhibitors.

scientific article published on 6 July 2005

Subtypes of the Type II Pit Pattern Reflect Distinct Molecular Subclasses in the Serrated Neoplastic Pathway

scientific article published on 15 March 2018

Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors

scientific article published on 11 June 2018

TET1 Depletion Induces Aberrant CpG Methylation in Colorectal Cancer Cells

scientific article

The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma.

scientific article published on 13 September 2013

UHRF1 depletion and HDAC inhibition reactivate epigenetically silenced genes in colorectal cancer cells

article

Upregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death.

scientific article published on May 2005

Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors

scientific article published on 18 January 2012

p53 negatively regulates the hepatoma growth factor HDGF.

scientific article published on 17 October 2011

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