List of works - Xin Chen

A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

scientific article published on 17 December 2021

Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice.

scientific article published on 8 February 2019

CDK9 is dispensable for YAP-driven hepatoblastoma development

scientific article published on 02 March 2020

Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma

scientific article published on 03 November 2020

Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans

scientific article published on 06 April 2019

Combined Treatment with MEK and mTOR Inhibitors is Effective in In Vitro and In Vivo Models of Hepatocellular Carcinoma

scientific article published on 03 July 2019

Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis

scientific article published on 10 February 2020

Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development

scientific article published on 21 June 2021

Focal adhesion kinase activation limits efficacy of Dasatinib in c-Myc driven hepatocellular carcinoma

scientific article published on 28 October 2018

Harnessing big 'omics' data and AI for drug discovery in hepatocellular carcinoma

scientific article published on 03 January 2020

MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment

scientific article published on 11 February 2019

Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.

scientific article

Oncogene-dependent function of BRG1 in hepatocarcinogenesis

scientific article published on 04 February 2020

Overexpression of SMAD7 activates the YAP/NOTCH cascade and promotes liver carcinogenesis in mice and humans

scientific article published on 24 December 2020

Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis

scientific article published on 11 November 2020

Potential dual functional roles of the Y-linked RBMY in hepatocarcinogenesis

scientific article published on 30 May 2020

Publisher Correction: Harnessing big 'omics' data and AI for drug discovery in hepatocellular carcinoma

scientific article published on 11 March 2020

Reply

Role of the mTOR pathway in liver cancer: from molecular genetics to targeted therapies

scientific article published on 11 May 2020

Selective targeting of MYC mRNA by stabilized antisense oligonucleotides

scientific article published on 14 October 2021

Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade.

scientific article published on 6 September 2017

The mTORC2-Akt1 Cascade Is Crucial for c-Myc to Promote Hepatocarcinogenesis in Mice and Humans

scientific article published on 21 June 2019

List of works by Xin Chen