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List of works by Vladimir I Titorenko

A laboratory test of evolutionary aging theories

scientific article published on 21 March 2017

A mitochondrially targeted compound delays aging in yeast through a mechanism linking mitochondrial membrane lipid metabolism to mitochondrial redox biology

scientific article published on 23 January 2014

A network of interorganellar communications underlies cellular aging

scientific article published on 02 July 2013

A new definition for the consensus sequence of the peroxisome targeting signal type 2.

scientific article published on July 2004

A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis

scientific article

A novel method for genetic transformation of yeast cells using oligoelectrolyte polymeric nanoscale carriers

scientific article published in January 2013

A quantitative assessment of the yeast lipidome using electrospray ionization mass spectrometry

scientific article published on 21 August 2009

A signal from inside the peroxisome initiates its division by promoting the remodeling of the peroxisomal membrane

scientific article

Acyl-CoA oxidase is imported as a heteropentameric, cofactor-containing complex into peroxisomes of Yarrowia lipolytica

scientific article

Aging and Age-related Disorders: From Molecular Mechanisms to Therapies

scientific article published on 03 July 2019

Bile acids induce apoptosis selectively in androgen-dependent and -independent prostate cancer cells

scientific article published on 8 August 2013

Caloric Restriction Extends Yeast Chronological Lifespan by Altering a Pattern of Age-Related Changes in Trehalose Concentration ⬇️

scientific article published on July 6, 2012

Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state

scientific article published on September 2017

Cell-Nonautonomous Mechanisms Underlying Cellular and Organismal Aging

scientific article published on 31 October 2015

Cell-autonomous mechanisms of chronological aging in the yeast Saccharomyces cerevisiae

scientific article published on 27 May 2014

Cells with impaired mitochondrial H2O2 sensing generate less •OH radicals and live longer

scientific article published on 19 February 2014

Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes

scientific article

Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes

scientific article

Dynamic ergosterol- and ceramide-rich domains in the peroxisomal membrane serve as an organizing platform for peroxisome fusion

scientific article published on February 2005

Effect of calorie restriction on the metabolic history of chronologically aging yeast

scientific article published on 17 June 2009

Empirical Validation of a Hypothesis of the Hormetic Selective Forces Driving the Evolution of Longevity Regulation Mechanisms

scientific article (publication date: 2016)

Empirical verification of evolutionary theories of aging

scientific article published on 25 October 2016

Essential roles of peroxisomally produced and metabolized biomolecules in regulating yeast longevity

scientific article published on January 2013

Guidelines and recommendations on yeast cell death nomenclature.

scientific article published in January 2018

Integration of peroxisomes into an endomembrane system that governs cellular aging ⬇️

scientific article published on July 17, 2012

Interspecies Chemical Signals Released into the Environment may Create Xenohormetic, Hormetic and Cytostatic Selective Forces that Drive the Ecosystemic Evolution of Longevity Regulation Mechanisms ⬇️

scientific article published on July 27, 2011

Isolation and characterization of peroxisomal protein import (Pim−) mutants ofHansenula polymorpha

scientific article published in 1992

Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan

scientific article

Lithocholic acid induces endoplasmic reticulum stress, autophagy and mitochondrial dysfunction in human prostate cancer cells.

scientific article

Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome

scientific article published on January 2015

Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells ⬇️

scientific article published on October 1, 2011

Longevity extension by phytochemicals

scientific article published on 13 April 2015

Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeostasis

scientific article published on April 2013

Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from "liponecrosis", a previously unknown form of programmed cell death

scientific article published on 28 October 2013

Mechanism of liponecrosis, a distinct mode of programmed cell death

scientific article published on January 2014

Mechanisms Underlying the Essential Role of Mitochondrial Membrane Lipids in Yeast Chronological Aging

scientific article

Mechanisms by which different functional states of mitochondria define yeast longevity

scientific article published on 11 March 2015

Mechanisms that Link Chronological Aging to Cellular Quiescence in Budding Yeast ⬇️

scientific article published on 02 July 2020

Mechanisms underlying the anti-aging and anti-tumor effects of lithocholic bile acid

scientific article

Mitochondria operate as signaling platforms in yeast aging

scientific article published on 27 February 2016

Mitochondrial membrane lipidome defines yeast longevity

scientific article published on July 2013

Molecular and Cellular Mechanisms of Aging and Age-related Disorders

scientific article published on 14 July 2018

Origin and spatiotemporal dynamics of the peroxisomal endomembrane system

scientific article published on 16 December 2014

Overproduction of translation elongation factor 1-alpha (eEF1A) suppresses the peroxisome biogenesis defect in a Hansenula polymorpha pex3 mutant via translational read-through

scientific article published on 10 April 2007

Peroxisome division in the yeast Yarrowia lipolytica is regulated by a signal from inside the peroxisome

scientific article

Purification of mitochondria from yeast cells

scientific article published on 24 August 2009

Quasi-programmed aging of budding yeast: a trade-off between programmed processes of cell proliferation, differentiation, stress response, survival and death defines yeast lifespan

scientific article published on January 2014

RNA interference of peroxisome-related genes in C. elegans: a new model for human peroxisomal disorders

scientific article published on 14 August 2002

Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells

scientific article

Some Metabolites Act as Second Messengers in Yeast Chronological Aging.

scientific article published on 15 March 2018

Specific changes in mitochondrial lipidome alter mitochondrial proteome and increase the geroprotective efficiency of lithocholic acid in chronologically aging yeast

scientific article published on 31 March 2017

The Intricate Interplay between Mechanisms Underlying Aging and Cancer

scientific article published on 16 February 2014

The peroxisome: orchestrating important developmental decisions from inside the cell

scientific article published on 23 February 2004

The spatiotemporal dynamics of longevity-defining cellular processes and its modulation by genetic, dietary, and pharmacological anti-aging interventions.

scientific article published on 31 October 2012

Very-long-chain fatty acid metabolic capacity of 17-beta-hydroxysteroid dehydrogenase type 12 (HSD17B12) promotes replication of hepatitis C virus and related flaviviruses

scientific article published on 04 March 2020

Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level ⬇️

scientific article published on August 1, 2010

Yeast Cells Exposed to Exogenous Palmitoleic Acid Either Adapt to Stress and Survive or Commit to Regulated Liponecrosis and Die.

scientific article

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