List of works by Caitlin M O'Connor

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth.

scientific article

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors

scientific article published on 20 September 2019

PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells

scientific article published on 01 July 2018

Protein phosphatase 2A Aα regulates Aβ protein expression and stability

scientific article published on 22 February 2019

Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45)

scientific article published on 27 September 2019

Splice of Life for Cancer: Missplicing of PPP2R5A by Mutant SF3B1 Leads to MYC Stabilization and Tumorigenesis

scientific article published on 01 June 2020

The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis

scientific article published on 29 May 2019

Therapeutic Targeting of PP2A.

scientific article

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