Search filters

List of works by Darren Plant

Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response

scientific article published on April 2015

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23

scientific article (publication date: November 2016)

Clinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis

scientific article published on May 2015

Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis.

scientific article published on February 2015

Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study S

scientific article published on 7 October 2012

Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels. ⬇️

scientific article published on 25 August 2016

Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis ⬇️

scientific article published on 27 January 2016

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment

scientific article published on 17 May 2013

Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients

scientific article published on June 2012

Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci

scientific article

HLA-A 31:01 is not associated with the development of methotrexate pneumonitis in the UK population: results from a genome-wide association study.

scientific article

High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort ⬇️

scientific article published on 31 May 2016

Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans

scientific article

Impact of inadequate adherence on response to subcutaneously administered anti-tumour necrosis factor drugs: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort

scientific article

Impact of psychological factors on subjective disease activity assessments in patients with severe rheumatoid arthritis

scientific article

Interaction analysis between HLA-DRB1 shared epitope alleles and MHC class II transactivator CIITA gene with regard to risk of rheumatoid arthritis

scientific article

Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples

scientific article

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci

scientific article published on 09 September 2009

Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients

scientific article published in April 2009

Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers

scientific article

Investigation of rheumatoid arthritis genetic susceptibility markers in the early rheumatoid arthritis study further replicates the TRAF1 association with radiological damage

scientific article

Latent class trajectory modelling of 2-components-DAS28 identifies multiple rheumatoid arthritis phenotypes of response to biologic disease modifying anti-rheumatic drugs

scientific article published on 31 May 2020

Pharmacogenetics of TNF inhibitor response in rheumatoid arthritis utilizing the two-component disease activity score

scientific article published on 30 October 2020

Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort ⬇️

scientific article published on 16 May 2016

Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility

scientific article published on 22 April 2008

Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort

scientific article

Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study

scientific article published on 18 March 2015

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.

scientific article published on 14 September 2008

Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis

scientific article

Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: a Mendelian randomisation approach

scientific article published on 9 December 2013

The predictive value of serum S100A9 and response to etanercept is not confirmed in a large UK rheumatoid arthritis cohort ⬇️

scientific article

The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register ⬇️

scientific article

Paulina is supported by:

About Paulina

Help