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List of works by Wayne Koch

Abstract 2482: Key tumor suppressor genes inactivated by promoter methylation and somatic mutations in head and neck cancer

article

Abstract B1-62: Bumphunting analysis identifies PAX5 promoter methylation and p53 somatic mutations in genomic instability pathways linked to very poor survival in head and neck cancer

Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features

scientific article

Decreased mitochondrial DNA content in posttreatment salivary rinses from head and neck cancer patients

scientific article published in March 2006

Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma

scientific article

DeltaNp63alpha up-regulates the Hsp70 gene in human cancer

scientific article

Detection of promoter hypermethylation in salivary rinses as a biomarker for head and neck squamous cell carcinoma surveillance

scientific article published on 31 May 2011

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

scientific article

Development and external validation of a risk-prediction model to predict 5-year overall survival in advanced larynx cancer.

scientific article published on 8 November 2017

Dysphagia in oropharyngeal squamous cell carcinoma in perspective

scientific article

Epstein-Barr virus in head and neck cancer assessed by quantitative polymerase chain reaction

scientific article

Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma.

scientific article published on January 2008

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

scientific article (publication date: 26 August 2011)

Feasibility of quantitative PCR-based saliva rinse screening of HPV for head and neck cancer.

scientific article

Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck

scientific article

Functional characterization of alternatively spliced GSN in head and neck squamous cell carcinoma

scientific article published on 26 July 2018

Identification of guanine nucleotide-binding protein γ-7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling ⬇️

scientific article published on 06 February 2013

Increased mitochondrial DNA content in saliva associated with head and neck cancer

scientific article published in April 2005

Increased plasma DNA integrity index in head and neck cancer patients

scientific article published in December 2006

Increasing prevalence of human papillomavirus-positive oropharyngeal cancers among older adults

scientific article published on 30 April 2018

Integrated analysis of whole-genome ChIP-Seq and RNA-Seq data of primary head and neck tumor samples associates HPV integration sites with open chromatin marks

scientific article published on 25 September 2017

Intraoperative molecular margin analysis in head and neck cancer

scientific article published on 01 January 2004

KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses

scientific article

Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer

scientific article

Mitochondrial DNA content increase in response to cigarette smoking

scientific article published in January 2006

Mitochondrial DNA mutation in normal margins and tumors of recurrent head and neck squamous cell carcinoma patients

scientific article published on 26 July 2010

Positive Correlation of Tissue Inhibitor of Metalloproteinase-3 and Death-Associated Protein Kinase Hypermethylation in Head and Neck Squamous Cell Carcinoma

scientific article published on 01 August 2007

Prognostic factors for human papillomavirus-positive and negative oropharyngeal carcinomas

scientific article published on 14 March 2018

Quality indicators of oropharyngeal cancer care in the elderly

scientific article published on 15 December 2017

Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission

scientific article published on June 2010

Real-time gap ligase chain reaction: a rapid semiquantitative assay for detecting p53 mutation at low levels in surgical margins and lymph nodes from resected lung and head and neck tumors

scientific article published on 01 April 2004

Short- and long-term outcomes of oropharyngeal cancer care in the elderly

scientific article published on 24 March 2018

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

scientific article

The Ligamp TP53 Assay for Detection of Minimal Residual Disease in Head and Neck Squamous Cell Carcinoma Surgical Margins

scientific article

Tissue imprint for molecular mapping of deep surgical margins in patients with head and neck squamous cell carcinoma ⬇️

scientific article published on January 3, 2012

Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity

scientific article published on 01 April 2004

Utility of preoperative fine needle aspiration in parotid lesions.

scientific article published on 7 August 2017

Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer

scientific article published on 16 December 2013

p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma ⬇️

scientific article published on December 15, 2010

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