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List of works by Faith E Davies

A clinical prediction model for outcome and therapy delivery in transplant-ineligible patients with myeloma (UK Myeloma Research Alliance Risk Profile): a development and validation study

scientific article published on 06 February 2019

A gene expression based predictor for high risk myeloma treated with intensive therapy and autologous stem cell rescue.

scientific article published on 19 August 2014

A global expression-based analysis of the consequences of the t(4;14) translocation in myeloma

scientific article published in September 2004

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

scientific article published in January 2019

A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma

scientific article

A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis

scientific article published on 01 September 2018

A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex

scientific article

A phase I/II study of KW-2478, an Hsp90 inhibitor, in combination with bortezomib in patients with relapsed/refractory multiple myeloma.

scientific article published on 5 September 2017

A stressful life (or death): Combinatorial proteotoxic approaches to cancer-selective therapeutic vulnerability ⬇️

scientific article published on April 1, 2011

Aetiology of bone disease and the role of bisphosphonates in multiple myeloma ⬇️

scientific article published on May 1, 2003

Anti-myeloma effects of ruxolitinib combined with bortezomib and lenalidomide: A rationale for JAK/STAT pathway inhibition in myeloma patients

scientific article

Antimyeloma activity of heat shock protein-90 inhibition.

scientific article published on 18 October 2005

As stressful as learning your ABC ⬇️

scientific article published on October 11, 2012

Assessing the effect of obesity-related traits on multiple myeloma using a Mendelian randomisation approach.

scientific article published on 16 June 2017

BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma

scientific article published on 27 January 2020

Bacteremias following autologous stem cell transplantation for multiple myeloma: Risk factors and outcomes

scientific article published on 15 February 2019

Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker

scientific article published on 24 February 2017

Biology and treatment of myeloma

scientific article published on September 2014

CD52 expression patterns in myeloma and the applicability of alemtuzumab therapy

scientific article published on 17 October 2006

Cardiovascular complications of multiple myeloma in the elderly.

scientific article published on 22 November 2017

Characterisation of immunoparesis in newly diagnosed myeloma and its impact on progression-free and overall survival in both old and recent myeloma trials ⬇️

scientific article published on 20 June 2018

Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients

scientific article published on 07 February 2019

Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma.

scientific article published on 11 August 2016

Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma.

scientific article published on 20 December 2018

Complete response to donor lymphocyte infusion in multiple myeloma is associated with antibody responses to highly expressed antigens ⬇️

scientific article published on October 16, 2003

Effect of general symptom level, specific adverse events, treatment patterns, and patient characteristics on health-related quality of life in patients with multiple myeloma: results of a European, multicenter cohort study

scientific article published on February 2014

European perspective on multiple myeloma treatment strategies in 2014

scientific article

European perspective on multiple myeloma treatment strategies: update following recent congresses

scientific article

Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma.

scientific article published on 27 February 2017

FRAX is a robust predictor of baseline vertebral fractures in multiple myeloma patients

scientific article published on 19 September 2018

Flow cytometric disease monitoring in multiple myeloma: the relationship between normal and neoplastic plasma cells predicts outcome after transplantation

scientific article published in November 2002

Flow cytometry defined cytoplasmic immunoglobulin index is a major prognostic factor for progression of asymptomatic monoclonal gammopathies to multiple myeloma (subset analysis of SWOG S0120).

scientific article published on 25 March 2016

Future directions of next-generation novel therapies, combination approaches, and the development of personalized medicine in myeloma.

scientific article published on 11 April 2011

Genomic characterization of the chromosomal breakpoints of t(4;14) of multiple myeloma suggests more than one possible aetiological mechanism

scientific article published in February 2003

Guidelines for the diagnosis and management of multiple myeloma 2011 ⬇️

scientific article published on May 14, 2011

Heat shock proteins in multiple myeloma

scientific article published on March 2014

High readmission rates are associated with a significant economic burden and poor outcome in patients with grade III/IV acute GvHD ⬇️

scientific article published on December 28, 2012

How to manage neutropenia in multiple myeloma

scientific article published on 16 December 2011

Hyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma.

scientific article

Identification of Autophosphorylation Inhibitors of the Inositol-Requiring Enzyme 1 Alpha (IRE1α) by High-Throughput Screening Using a DELFIA Assay ⬇️

scientific article published on November 8, 2012

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

scientific article published on 08 June 2018

Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma

scientific article

Inherited genetic susceptibility to monoclonal gammopathy of unknown significance

scientific article published on 21 January 2014

Inhibiting the molecular evolution of cancer through HSP90 ⬇️

scientific article published on October 1, 2012

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.

scientific article

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

scientific article published on 02 July 2013

Is molecular remission the goal of multiple myeloma therapy?

scientific article published in December 2017

Kinase domain activation through gene rearrangement in multiple myeloma.

scientific article published on 23 March 2018

Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial

scientific article published on 14 December 2018

Long-term outcomes after autologous stem cell transplantation for multiple myeloma

scientific article published on 01 January 2020

MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma.

scientific article published on 6 July 2018

Maintenance Treatment and Survival in Patients With Myeloma: A Systematic Review and Network Meta-analysis

scientific article published on 01 October 2018

Mesenchymal stem cells gene signature in high-risk myeloma bone marrow linked to suppression of distinct IGFBP2-expressing small adipocytes

article

Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: impact on outcome in the Medical Research Council Myeloma IX Study

scientific article published on 3 June 2013

Minimal residual disease following autologous stem cell transplant in myeloma: impact on outcome is independent of induction regimen

scientific article published on 15 October 2015

Minimal residual disease in myeloma by flow cytometry: independent prediction of survival benefit per log reduction

scientific article

Minimal residual disease monitoring in multiple myeloma.

scientific article

Neutral tumor evolution in myeloma is associated with poor prognosis. ⬇️

scientific article published on 21 August 2017

Oncogenic RAC1 and NRAS drive resistance to endoplasmic reticulum stress through MEK/ERK signalling.

scientific article published on 9 January 2018

Personalized therapy in multiple myeloma according to patient age and vulnerability: a report of the European Myeloma Network (EMN).

scientific article published on 12 August 2011

Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of

scientific article published on 22 January 2019

Practical Considerations for Antibodies in Myeloma

scientific article published on 01 May 2018

Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients. ⬇️

scientific article published on 06 June 2017

Quality of life during and following sequential treatment of previously untreated patients with multiple myeloma: findings of the Medical Research Council Myeloma IX randomised study ⬇️

scientific article published on 09 July 2018

Reply to M. Roschewski et al.

scientific article published on 13 January 2014

Response evaluation and monitoring of multiple myeloma

scientific article published on February 2014

Response-adapted intensification with cyclophosphamide, bortezomib, and dexamethasone versus no intensification in patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial

scientific article published on 14 October 2019

Role of magnetic resonance imaging in the management of patients with multiple myeloma: a consensus statement

scientific article published on 20 January 2015

Second malignancies in the context of lenalidomide treatment: an analysis of 2732 myeloma patients enrolled to the Myeloma XI trial. ⬇️

scientific article published on 9 December 2016

Serum free light chain levels and renal function at diagnosis in patients with multiple myeloma

scientific article published on 13 July 2018

Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

scientific article published on 16 August 2017

Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response ⬇️

scientific article published on February 11, 2011

Sub-clonal copy number is associated with prognosis in multiple myeloma

scientific article published on 29 October 2018

Thalidomide for patients with relapsed multiple myeloma after high-dose chemotherapy and stem cell transplantation: results of an open-label multicenter phase 2 study of efficacy, toxicity, and biological activity

scientific article published in July 2004

The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells

scientific article published on 5 December 2014

The Pattern of Mesenchymal Stem Cell Expression Is an Independent Marker of Outcome in Multiple Myeloma

scientific article published on 21 March 2018

The Role of Minimal Residual Disease Testing in Myeloma Treatment Selection and Drug Development: Current Value and Future Applications

scientific article

The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma. ⬇️

scientific article published on 27 May 2016

The bone marrow microenvironment influences the differential chemokine receptor expression of normal and neoplastic plasma cells

scientific article published on 01 June 2005

The combination of HDAC and aminopeptidase inhibitors is highly synergistic in myeloma and leads to disruption of the NFκB signalling pathway

scientific article published on July 2015

The genomic landscape of plasma cells in systemic light chain amyloidosis

scientific article published on 16 November 2018

The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma.

scientific article published on 26 May 2017

The relative importance of factors predicting outcome for myeloma patients at different ages: results from 3894 patients in the Myeloma XI trial

scientific article published on 14 October 2019

The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis ⬇️

scientific article published on October 20, 2011

The role of next generation sequencing in infection prevention in human parainfluenza virus 3 infections in immunocompromised patients.

scientific article published on 12 May 2017

The safety of pomalidomide for the treatment of multiple myeloma

scientific article published on 25 February 2016

The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma

scientific article published on 26 May 2017

The use of biological variables to predict outcome in multiple myeloma ⬇️

scientific article published on December 1, 1997

The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma

scientific article

The vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584 inhibits growth and migration of multiple myeloma cells in the bone marrow microenvironment

scientific article

Toward personalized treatment in multiple myeloma based on molecular characteristics

scientific article published on 26 December 2018

Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients

scientific article

Update on the optimal use of bortezomib in the treatment of multiple myeloma

scientific article

Whole-body diffusion-weighted MRI: a new gold standard for assessing disease burden in patients with multiple myeloma?

scientific article published on 09 December 2015

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