List of works - Timothy A Chan

A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma

scientific article published in 2022

A pan-cancer analysis of PBAF complex mutations and their association with immunotherapy response

scientific article published on 20 August 2020

ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup

scientific article published in Nature Communications

Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.

scientific article published on 13 March 2018

Author Correction: Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling

correction of a scholarly article

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

scientific article published on 01 March 2020

Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy

scientific article published on 07 November 2019

Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity

scientific article published in 2022

G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma

scientific article published on 26 February 2019

Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response

scientific article published on 01 May 2019

HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice

scientific article published on 17 August 2020

Immunogenic neoantigens derived from gene fusions stimulate T cell responses

scientific article published on 22 April 2019

Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence.

scientific article published on 27 November 2017

Mutations in <i>BRCA1</i> and <i>BRCA2</i> differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy

scientific article published on 16 November 2020

Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy

scientific article

RIG-I activation is critical for responsiveness to checkpoint blockade

scientific article published on 01 September 2019

TGF-β suppresses type 2 immunity to cancer

scientific article published on 21 October 2020

Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas

scientific article published on 22 April 2020

The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy

scientific article published on 01 March 2019

The hallmarks of successful anticancer immunotherapy

scientific article published on 01 September 2018

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

scientific article published on 14 January 2019

List of works by Timothy A Chan