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List of works by Nobuyoshi Hiraoka

A Novel Multivariate Index for Pancreatic Cancer Detection Based On the Plasma Free Amino Acid Profile

scientific article published on 2 July 2015

A Single-Institution Validation Study of Lymph Node Staging By the AJCC 8th Edition for Patients with Pancreatic Head Cancer: A Proposal to Subdivide the N2 Category

scientific article published on 29 April 2019

A Tumor-targeting Adenovirus with High Gene-transduction Efficiency for Primary Pancreatic Cancer and Ascites Cells

scientific article

A case of acinar cell adenocarcinoma in the pancreatic tail

scientific article

A case of adenocarcinoma with enteroblastic differentiation of the ampulla of Vater

scientific article published on 27 March 2016

A case of neurilemoma at the celiac tripod

scientific article published on 01 September 2008

A combination of molecular markers and clinical features improve the classification of pancreatic cysts

scientific article

A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.

scientific article published on 24 May 2014

A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans

scientific article

A significant subgroup of resectable gallbladder cancer patients has an HER2 positive status.

scientific article

A targeting ligand enhances infectivity and cytotoxicity of an oncolytic adenovirus in human pancreatic cancer tissues.

scientific article

A tissue microRNA signature that predicts the prognosis of breast cancer in young women

scientific article published on 15 November 2017

A yolk sac tumor of the pancreas and derived xenograft model effectively responded to VIP chemotherapy

scientific article published on 31 December 2019

Aberrant DNA methylation results in altered gene expression in non-alcoholic steatohepatitis-related hepatocellular carcinomas

scientific article published on 19 July 2020

Adenylate cyclase-associated protein 1 overexpressed in pancreatic cancers is involved in cancer cell motility

scientific article

All-Exon TP53 Sequencing and Protein Phenotype Analysis Accurately Predict Clinical Outcome after Surgical Treatment of Head and Neck Squamous Cell Carcinoma

scientific article published on 21 March 2019

An Oncogenic ALK Fusion and an RRAS Mutation in KRAS Mutation-Negative Pancreatic Ductal Adenocarcinoma

scientific article published on 6 February 2017

An extremely rare clinical manifestation of gallbladder cancer presenting with abdominal wall invasion with an erythematous skin break

scientific article published on 11 January 2016

Antibody-based proteomics to identify an apoptosis signature for early recurrence of hepatocellular carcinoma

scientific article published on 24 October 2016

Arginase II Expressed in Cancer-Associated Fibroblasts Indicates Tissue Hypoxia and Predicts Poor Outcome in Patients with Pancreatic Cancer ⬇️

scientific article published on February 12, 2013

Association of pancreatic Fatty infiltration with pancreatic ductal adenocarcinoma.

scientific article published on 13 March 2014

Basing treatment strategy for non-functional pancreatic neuroendocrine tumors on tumor size

scientific article published on 18 April 2014

Bile duct carcinoma involving the common channel associated with pancreaticobiliary maljunction shows an extension pattern similar to ductal carcinoma of the pancreas ⬇️

scientific article published on August 1, 2013

CD20+ tumor-infiltrating immune cells and CD204+ M2 macrophages are associated with prognosis in thymic carcinoma

scientific article published on 11 April 2020

CIC break-apart fluorescence in-situ hybridization misses a subset of CIC-DUX4 sarcomas: a clinicopathological and molecular study.

scientific article published on 11 May 2017

CIC-rearranged Sarcomas: A Study of 20 Cases and Comparisons With Ewing Sarcomas

scientific article published on 17 December 2015

CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation

scientific article published on 25 May 2010

Calcifying nested stromal epithelial tumor of the liver in a patient with Klinefelter syndrome: a case report and review of the literature

Carcinoid tumor arising in a duplication cyst of the duodenum

scientific article

Characterizing the Effect of Automated Cell Sorting Solutions on Cytomorphological Changes

scientific article published on 24 June 2019

Cisplatin and etoposide as first-line chemotherapy for poorly differentiated neuroendocrine carcinoma of the hepatobiliary tract and pancreas

scientific article published on 4 January 2010

Clarifying the Distinction Between Malignant Peripheral Nerve Sheath Tumor and Dedifferentiated Liposarcoma: A Critical Reappraisal of the Diagnostic Utility of MDM2 and H3K27me3 Status

scientific article published on 5 January 2018

Clinical impact of a cytological screening system using cyclin D1 immunostaining and genomic analysis for the diagnosis of thyroid nodules

scientific article published on 18 March 2019

Clinical significance of frozen section analysis during resection of intraductal papillary mucinous neoplasm: should a positive pancreatic margin for adenoma or borderline lesion be resected additionally?

scientific article published on 19 September 2009

Clinical significance of tumor-infiltrating immune cells focusing on BTLA and Cbl-b in patients with gallbladder cancer

scientific article

Clinicopathologic Association and Prognostic Value of Microcystic, Elongated, and Fragmented (MELF) Pattern in Endometrial Endometrioid Carcinoma.

scientific article published on 17 April 2017

Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities

scientific article published on 3 March 2017

Clinicopathological impacts of DNA methylation alterations on pancreatic ductal adenocarcinoma: prediction of early recurrence based on genome-wide DNA methylation profiling

scientific article published on 26 February 2021

Clinicopathological significance of core 3 O-glycan synthetic enzyme, β1,3-N-acetylglucosaminyltransferase 6 in pancreatic ductal adenocarcinoma

scientific article published on 30 November 2020

Clinicopathological, Immunohistochemical, and Genetic Features of Primary Lung Adenocarcinoma Occurring in the Setting of Usual Interstitial Pneumonia Pattern

scientific article published on 26 August 2016

Comprehensive characterization of RSPO fusions in colorectal traditional serrated adenomas

scientific article

Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing

scientific article published on 30 October 2003

Cytoplasmic MSH2 immunoreactivity in a patient with Lynch syndrome with an EPCAM-MSH2 fusion

scientific article published on 19 October 2016

DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas

scientific article

Dedifferentiated Liposarcoma With Epithelioid/Epithelial Features

scientific article published on 17 July 2017

Details of HER2 status in 454 cases of biliary tract cancer

scientific article published on 03 September 2020

Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis

scientific article

Early venous return in hepatic angiomyolipoma due to an intratumoral structure resembling an arteriovenous fistula ⬇️

scientific article published on June 20, 2013

Effector T-cell infiltration positively impacts survival of glioblastoma patients and is impaired by tumor-derived TGF-β.

scientific article

Effects of the Storage Solution Type and Prolonged Storage on the Immunoreactivity of Cells

scientific article published on 09 October 2019

Epigenetic landscape influences the liver cancer genome architecture.

scientific article published on 24 April 2018

Erratum: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

scientific article published on 01 May 2016

Establishment of Patient-Derived Organoids and Drug Screening for Biliary Tract Carcinoma

scientific article published on 01 April 2019

Establishment of six new human biliary tract carcinoma cell lines and identification of MAGEH1 as a candidate biomarker for predicting the efficacy of gemcitabine treatment

scientific article

Evaluation of the degree of pancreatic fatty infiltration by area-based assessment of CT images: comparison with histopathology-based and CT attenuation index-based assessments.

scientific article published on 31 August 2016

Expression and gene amplification of actinin-4 in invasive ductal carcinoma of the pancreas

scientific article published on September 2008

Expression of classical HLA class I antigens, HLA-E, and HLA-G is adversely prognostic in pancreatic cancer patients

scientific article published on 03 June 2020

Extraskeletal osteosarcoma: MDM2 and H3K27me3 analysis of 19 cases suggest disease heterogeneity.

scientific article published on 28 February 2018

FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis

scientific article published in February 2007

Feasibility and utility of a panel testing for 114 cancer-associated genes in a clinical setting: A hospital-based study

article

Feasibility of Routine Application of Gadoxetic Acid-Enhanced MRI in Combination with Diffusion-Weighted MRI for the Preoperative Evaluation of Colorectal Liver Metastases

scientific article published on 29 June 2016

Feasibility of genomic profiling with next-generation sequencing using specimens obtained by image-guided percutaneous needle biopsy

scientific article published on 01 April 2019

Forkhead box P3 regulatory T cells coexisting with cancer associated fibroblasts are correlated with a poor outcome in lung adenocarcinoma

scientific article published on 19 February 2013

Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma.

scientific article published on 9 April 2016

Frequent false-negative immunohistochemical staining with IDH1 (R132H)-specific H09 antibody on frozen section control slides: a potential pitfall in glioma diagnosis

scientific article published on 05 December 2018

Gemcitabine in patients with intraductal papillary mucinous neoplasm with an associated invasive carcinoma of the pancreas

scientific article published on 01 July 2013

Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma

scientific article

Genomic characterization of malignant progression in neoplastic pancreatic cysts

scientific article published on 14 August 2020

Genomic spectra of biliary tract cancer.

scientific article

Giant lamellar bodies associated with adenocarcinoma of the lung

scientific article published on 2 August 2016

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival.

scientific article published on 19 April 2018

H3K27me3 deficiency defines a subset of dedifferentiated chondrosarcomas with characteristic clinicopathological features

scientific article published on 05 October 2018

Heat Shock Protein 90 Is a Potential Therapeutic Target in Cholangiocarcinoma

scientific article

Histopathological characteristics of hypervascular cholangiocellular carcinoma as an early stage of cholangiocellular carcinoma

scientific article

IAP inhibitor, Embelin increases VCAM-1 levels on the endothelium, producing lymphocytic infiltration and antitumor immunity

scientific article published on 27 October 2020

INSM1 expression and its diagnostic significance in extraskeletal myxoid chondrosarcoma

scientific article published on 12 January 2018

Identification of 27 5' CpG islands aberrantly methylated and 13 genes silenced in human pancreatic cancers

scientific article

Immunohistochemistry for trimethylated H3K27 in the diagnosis of malignant peripheral nerve sheath tumours

scientific article published on 31 August 2016

Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas.

scientific article published in August 2008

Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas

scientific article

Infrequent mismatch repair protein loss in gallbladder cancer patients in Japan

scientific article

Integrative characterization of intraductal tubulopapillary neoplasm (ITPN) of the pancreas and associated invasive adenocarcinoma

scientific article published in 2022

Intraductal carcinoma component as a favorable prognostic factor in biliary tract carcinoma

scientific article

Intraductal carcinosarcoma with a heterologous mesenchymal component originating in intraductal papillary-mucinous carcinoma (IPMC) of the pancreas with both carcinoma and osteosarcoma cells arising from IPMC cells

scientific article published in March 2010

Intraductal dissemination of papillary adenocarcinoma of the ampulla of Vater in the pancreatic duct

scientific article published in January 2014

Intraductal tubular carcinoma in an adenoma of the main pancreatic duct of the pancreas head

scientific article published on 01 July 2006

Invasive biliary cystic tumor without ovarian-like stroma

scientific article published in December 2007

Invasive breast cancers in adolescent and young adult women show more aggressive immunohistochemical and clinical features than those in women aged 40-44 years

scientific article published on 11 December 2018

Invasive carcinoma originating in an intraductal papillary mucinous neoplasm of the pancreas: a clinicopathologic comparison with a common type of invasive ductal carcinoma

scientific article published on 01 April 2006

Knowledge discovery for pancreatic cancer using inductive logic programming

scientific article published in August 2014

Left hepatic trisectionectomy for perihilar cholangiocarcinoma with a right-sided round ligament: A case report

scientific article published on 01 February 2020

Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis

scientific article

Local Administration of GITR Agonistic Antibody Induces a Stronger Antitumor Immunity than Systemic Delivery

scientific article published on 03 April 2019

Long-term recurrence-free survival in a patient with primary hepatic carcinosarcoma: case report with a literature review

scientific article published on 03 October 2009

Macroscopic features predict outcome in patients with pancreatic ductal adenocarcinoma

scientific article published on 05 October 2016

Methods for Measuring and Staging a Uterine Cervical Adenocarcinoma Showing Intracystic Papillary Growth: A Case Report

scientific article published on 11 July 2017

Minimally invasive intraductal papillary-mucinous carcinoma of the pancreas: clinicopathologic study of 104 intraductal papillary-mucinous neoplasms

scientific article published on 01 February 2008

Mismatch repair deficiency commonly precedes adenoma formation in Lynch Syndrome-Associated colorectal tumorigenesis

scientific article published on 26 May 2017

Molecular mechanisms of uterine leiomyosarcomas: involvement of defect in LMP2 expression.

scientific article published on 22 July 2008

Multiple Intraglandular Metastases in a Patient with Invasive Ductal Carcinoma of the Pancreas

scientific article

Myoepithelioma-like Tumors of the Vulvar Region: A Distinctive Group of SMARCB1-deficient Neoplasms

scientific article

N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules

scientific article published on 9 October 2005

Natural History of Epithelioid Hemangioendothelioma of the Liver: CT Findings of 15 Cases

scientific article published on 18 May 2020

PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors

scientific article

Pancreatic Intraglandular Metastasis Predicts Poorer Outcome in Postoperative Patients With Pancreatic Ductal Carcinoma ⬇️

scientific article published on 01 July 2013

Pancreatic ducts as an important route of tumor extension for acinar cell carcinoma of the pancreas

scientific article

Pancreatic neuroendocrine tumors: A single-center 20-year experience with 100 patients

scientific article

Pancreaticojejunostomy with invagination of the punched pancreatic remnant after medial pancreatectomy and enucleation for multiple metastases of renal cell carcinoma: report of a case

scientific article published on 08 December 2009

Periductal induction of high endothelial venule-like vessels in type 1 autoimmune pancreatitis

scientific article published on 01 January 2013

Plasma membrane expression of ZNF185 is a prognostic factor in pancreatic ductal carcinoma

scientific article

Postoperative acute multiple organ failure after hepatectomy in a Nigerian male with sickle cell trait: a case report

scientific article published in 2021

Potential diagnostic biomarkers: differential expression of LMP2/β1i and cyclin B1 in human uterine leiomyosarcoma

scientific article

Preoperative evaluation of invasive and noninvasive intraductal papillary-mucinous neoplasms of the pancreas: clinical, radiological, and pathological analysis of 123 cases

scientific article published on 01 January 2009

Pretreatment Immune Status Correlates with Progression-Free Survival in Chemotherapy-Treated Metastatic Colorectal Cancer Patients

scientific article published on 28 April 2016

Primary Retroperitoneal Myxoid Liposarcomas

scientific article published on 06 May 2016

Primary adenocarcinoma of the rete testis with preceding diagnosis of pulmonary metastases

scientific article published on 01 December 2006

Prognostic Impact of Margin Distance and Tumor Spread Through Air Spaces in Limited Resection for Primary Lung Cancer

scientific article published on 4 September 2017

Prognostic factors for patients with early-stage uterine serous carcinoma without adjuvant therapy.

scientific article published on 19 February 2018

Prognostic significance of HLA class I and II expression in patients with diffuse large B cell lymphoma treated with standard chemoimmunotherapy

scientific article

Prognostic value of tumor architecture, tumor-associated vascular characteristics, and expression of angiogenic molecules in pancreatic endocrine tumors

scientific article published on 01 January 2007

Proteomic profiling reveals the prognostic value of adenomatous polyposis coli-end-binding protein 1 in hepatocellular carcinoma

scientific article

Randomized phase II study of chemoradiotherapy with versus without induction chemotherapy for locally advanced pancreatic cancer: Japan Clinical Oncology Group trial, JCOG1106

scientific article published on 07 November 2020

Reappraisal of the clinical significance of tumor size in patients with pancreatic ductal carcinoma

scientific article published in October 2006

Reappraisal of the genetic heterogeneity of sessile serrated adenoma/polyp

scientific article published on 02 August 2018

Reduction of intrapancreatic neural density in cancer tissue predicts poorer outcome in pancreatic ductal carcinoma

scientific article published on 19 March 2019

Reliable evaluation of tumor-infiltrating lymphocytes in pancreatic cancer tissue biopsies

Resequencing analysis of the human tyrosine kinase gene family in pancreatic cancer

scientific article

Role of medial pancreatectomy in the management of intraductal papillary mucinous neoplasms and islet cell tumors of the pancreatic neck and body

scientific article published on 21 February 2008

SMARCB-1 deficient squamous cell carcinoma of a mediastinal cyst

scientific article published on 14 September 2018

SOX10 Expression as Well as BRAF and GNAQ/11 Mutations Distinguish Pigmented Ciliary Epithelium Neoplasms From Uveal Melanomas

scientific article published in October 2017

Slow growth of small pancreatic carcinoma with a 20-04 follow-up

scientific article published on 01 April 2009

Small Nucleolar Noncoding RNA SNORA23, Up-Regulated in Human Pancreatic Ductal Adenocarcinoma, Regulates Expression of Spectrin Repeat-Containing Nuclear Envelope 2 to Promote Growth and Metastasis of Xenograft Tumors in Mice

scientific article published on 5 April 2017

Solid-pseudopapillary neoplasms of the pancreas in men and women: do they differ?

scientific article

Solitary hepatic lymphangioma: Report of a case ⬇️

scientific article published on August 26, 2010

Steatotic and nonsteatotic scirrhous hepatocellular carcinomas reveal distinct clinicopathological features

scientific article published on 28 December 2018

Strong antitumor efficacy of a pancreatic tumor-targeting oncolytic adenovirus for neuroendocrine tumors

scientific article published on 21 September 2017

Superficially serrated adenoma: a proposal for a novel subtype of colorectal serrated lesion

scientific article published on 22 May 2018

Synchronous Double Bile Duct Cancers with Distinct Genetic Features

scientific article published on 02 June 2020

TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast

scientific article

Tertiary Lymphoid Organs in Cancer Tissues

scientific article

The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas.

scientific article published on December 2008

The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy

scientific article published on 30 May 2017

The role of tregs in human glioma patients and their inhibition with a novel STAT-3 inhibitor.

scientific article published on January 2009

Tissue amino acid profiles are characteristic of tumor type, malignant phenotype, and tumor progression in pancreatic tumors

scientific article published on 08 July 2019

Tumor-associated CD204+ M2 macrophages is an unfavorable prognosticator in uterine cervical adenocarcinoma

scientific article published on 22 December 2017

Tumor-infiltrating lymphocytes and hepatocellular carcinoma: molecular biology

scientific article published on 06 October 2010

Twenty-six cases of advanced ampullary adenocarcinoma treated with systemic chemotherapy

scientific article published on 30 January 2014

Two rare cases of endosalpingiosis in the axillary sentinel lymph nodes: evaluation of immunohistochemical staining and one-step nucleic acid amplification (OSNA) assay in patients with breast cancer

scientific article published on 12 February 2019

Upregulated SMAD3 promotes epithelial-mesenchymal transition and predicts poor prognosis in pancreatic ductal adenocarcinoma

scientific article published on 7 April 2014

Uterine adenosarcoma in Japan: Clinicopathologic features, diagnosis and management.

scientific article published on 14 February 2018

Utility of Assessing the Number of Mutated KRAS, CDKN2A, TP53, and SMAD4 Genes Using a Targeted Deep Sequencing Assay as a Prognostic Biomarker for Pancreatic Cancer.

scientific article

WNT Pathway Gene Mutations Are Associated With the Presence of Dysplasia in Colorectal Sessile Serrated Adenoma/Polyps

scientific article published on 13 June 2017

Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.

scientific article published on 11 April 2016

[Mucinous carcinoma of the pancreas]

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