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List of works by Irene Ghobrial

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

scientific article published in Nature Communications

6q deletion discriminates Waldenström macroglobulinemia from IgM monoclonal gammopathy of undetermined significance

scientific article

A Multicenter Phase II Study of Single-Agent Enzastaurin in Previously Treated Waldenstrom Macroglobulinemia

scientific article published on 09 August 2012

A Phase 1/2 Study of evofosfamide, A Hypoxia-Activated Prodrug with or without Bortezomib in Subjects with Relapsed/Refractory Multiple Myeloma

article

A Phase Ib/II Study of Oprozomib in Patients with Advanced Multiple Myeloma and Waldenström Macroglobulinemia

scientific article published on 29 May 2019

A Phase Ib/II Trial of the First-in-Class Anti-CXCR4 Antibody Ulocuplumab in Combination with Lenalidomide or Bortezomib Plus Dexamethasone in Relapsed Multiple Myeloma

scientific article published on 31 October 2019

A novel in vivo model for studying conditional dual loss of BLIMP-1 and p53 in B-cells, leading to tumor transformation

scientific article

A phase 2 study of modified lenalidomide, bortezomib and dexamethasone in transplant-ineligible multiple myeloma

scientific article published on 08 May 2018

A phase 2 trial of lenalidomide, bortezomib, and dexamethasone in patients with relapsed and relapsed/refractory myeloma

scientific article

A phase I safety study of enzastaurin plus bortezomib in the treatment of relapsed or refractory multiple myeloma

scientific article

ASH evidence-based guidelines: what is the role of maintenance therapy in the treatment of multiple myeloma?

scientific article published on January 2009

Aberrant Levels of miRNAs in Bone Marrow Microenvironment and Peripheral Blood of Myeloma Patients and Disease Progression

scientific article

Acute lymphoblastic leukemia as a clonally unrelated second primary malignancy after multiple myeloma

scientific article published on 19 July 2018

Advances in the treatment of monoclonal gammopaties: The emerging role of targeted therapy in plasma cell dyscrasias.

scientific article published in September 2008

Altered cytokine and chemokine profiles in multiple myeloma and its precursor disease

scientific article

American Society of Hematology Annual Meeting 2014: highlights in multiple myeloma

scientific article published on 24 March 2015

An In Vitro Differentiation Protocol for Human Embryonic Bipotential Gonad and Testis Cell Development

scientific article published on 10 November 2020

An asymptomatic 61‐year‐old man with BCR‐ABL‐positive bone marrow following autologous transplantation for multiple myeloma ⬇️

scientific article published on December 1, 2010

Antibody dependent cellular phagocytosis by macrophages is a novel mechanism of action of elotuzumab

scientific article published on 13 April 2018

Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma

scientific article published on 25 October 2019

Are you sure this is Waldenstrom macroglobulinemia?

scientific article published on January 1, 2012

Attenuated response to SARS-CoV-2 vaccine in patients with asymptomatic precursor stages of multiple myeloma and Waldenstrom macroglobulinemia

Author Correction: Mitochondrial metabolism promotes adaptation to proteotoxic stress

scientific article published on 01 July 2019

Autologous graft versus myeloma: it's not a myth

scientific article published on 19 November 2018

Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis

BELLINI: a renaissance for an era of precision therapy in multiple myeloma

scientific article published on 29 October 2020

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

scientific article (publication date: 16 September 2011)

BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.

scientific article published on April 2013

BM mesenchymal stromal cell–derived exosomes facilitatemultiple myeloma progression

scientific article

Balancing risk versus benefit in the treatment of Waldenström's Macroglobulinemia patients with nucleoside analogue-based therapy

scientific article published on 01 March 2009

Beyond single-agent bortezomib: combination regimens in relapsed multiple myeloma

scientific article published on November 2006

Biological and Clinical Implications of Clonal Heterogeneity and Clonal Evolution in Multiple Myeloma

scientific article

Biological properties of extracellular vesicles and their physiological functions.

scientific article published on 14 May 2015

Biology, prognosis, and therapy of Waldenström Macroglobulinemia

scientific article published on January 2015

Biomarkers of bone remodeling in multiple myeloma patients to tailor bisphosphonate therapy

scientific article published on 23 June 2014

Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression

scientific article published on 14 May 2018

Bone Marrow Stroma and Vascular Contributions to Myeloma Bone Homing.

scientific article published on 9 September 2017

Bone marrow biopsy in low-risk monoclonal gammopathy of undetermined significance reveals a novel smoldering multiple myeloma risk group

scientific article published on 06 March 2019

Bone marrow niches in haematological malignancies

scientific article published on 28 February 2020

Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1.

scientific article published on 20 January 2017

Bortezomib and Waldenstrom's macroglobulinemia

scientific article published on 01 April 2009

Bortezomib in the front-line treatment of multiple myeloma

scientific article published on July 2008

Bortezomib in the management of multiple myeloma ⬇️

scientific article published on September 8, 2009

Bortezomib overcomes the negative impact of CXCR4 mutations on survival of Waldenstrom's Macroglobulinemia patients

scientific article published on 26 October 2018

Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice

scientific article published on 12 December 2016

C1013G/CXCR4 acts as a driver mutation of tumor progression and modulator of drug resistance in lymphoplasmacytic lymphoma

scientific article published on 07 April 2014

CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation

scientific article published on 16 July 2015

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.

scientific article

Cancer Cell Dissemination and Homing to the Bone Marrow in a Zebrafish Model.

scientific article published on 7 January 2016

Candidate genes of Waldenström's macroglobulinemia: current evidence and research.

scientific article published on 17 July 2013

Carfilzomib, rituximab, and dexamethasone (CaRD) treatment offers a neuropathy-sparing approach for treating Waldenström's macroglobulinemia

scientific article published on 23 May 2014

Carfilzomib-dependent selective inhibition of the chymotrypsin-like activity of the proteasome leads to antitumor activity in Waldenstrom's Macroglobulinemia.

scientific article published on 25 February 2011

Cell Trafficking in Multiple Myeloma

scientific article published on February 2012

Cell autonomous and microenvironmental regulation of tumor progression in precursor states of multiple myeloma

scientific article published on 20 April 2016

Central nervous system involvement by Waldenström macroglobulinaemia (Bing-Neel syndrome): a multi-institutional retrospective study.

scientific article

Chemokines in multiple myeloma

scientific article published on October 2006

Choice of Therapy for Patients With Waldenström Macroglobulinemia ⬇️

scientific article published on December 10, 2012

Citron Rho-interacting kinase silencing causes cytokinesis failure and reduces tumor growth in multiple myeloma

scientific article published on 01 April 2019

Clinical Controversies in the Management of Smoldering Multiple Myeloma

scientific article published on 01 March 2020

Clinical and pathological prognostic markers for survival in adult patients with post-transplant lymphoproliferative disorders in solid transplant

scientific article published on 01 September 2008

Clinical and translational studies of a phase II trial of the novel oral Akt inhibitor perifosine in relapsed or relapsed/refractory Waldenstrom's macroglobulinemia

scientific article

Clinical challenges associated with bortezomib therapy in multiple myeloma and Waldenströms Macroglobulinemia

scientific article

Clinical outcome of patients with subcutaneous panniculitis-like T-cell lymphoma

scientific article

Clinical perspective: Linking psychosocial care to the disease continuum in patients with multiple myeloma

scientific article

Clinical relevance of soluble HLA class I molecules in Waldenstrom Macroglobulinemia

scientific article published on 10 March 2008

Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant

scientific article published on 12 June 2020

Clonal hematopoiesis is associated with increased risk of progression of asymptomatic Waldenström macroglobulinemia

Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma

scientific article published on November 2006

Conflicts of interest, authorship, and disclosures in industry-related scientific publications

scientific article

Correction: Resveratrol Exerts Antiproliferative Activity and Induces Apoptosis in Waldenström Macroglobulinemia

scientific article published on 01 August 2019

Current use of monoclonal antibodies in the treatment of multiple myeloma.

scientific article

Cyclophosphamide, bortezomib, and dexamethasone combination in waldenstrom macroglobulinemia

scientific article published on 10 May 2015

Defining the role of TORC1/2 in multiple myeloma ⬇️

scientific article published on December 22, 2011

Development of extramedullary myeloma in the era of novel agents: no evidence of increased risk with lenalidomide-bortezomib combinations

scientific article published on June 2015

Dietary Pattern and Risk of Multiple Myeloma in Two Large Prospective US Cohort Studies

scientific article published on 27 April 2019

Dissecting racial disparities in multiple myeloma

scientific article published on 17 February 2020

Does My Patient with a Serum Monoclonal Spike have Multiple Myeloma? ⬇️

scientific article published on April 1, 2012

Drug-Related Pneumonitis During Mammalian Target of Rapamycin Inhibitor Therapy: Radiographic Pattern-Based Approach in Waldenström Macroglobulinemia as a Paradigm

scientific article

Dual targeting of the PI3K/Akt/mTOR pathway as an antitumor strategy in Waldenstrom macroglobulinemia.

scientific article

Dual targeting of the proteasome regulates survival and homing in Waldenstrom macroglobulinemia

scientific article published on 3 March 2008

Dynamic interplay between bone and multiple myeloma: emerging roles of the osteoblast

scientific article

Efficacy of the oral mTORC1 inhibitor everolimus in relapsed or refractory indolent lymphoma

scientific article

Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma

scientific article

Emerging drugs in multiple myeloma

scientific article published on March 2007

Endoplasmic reticulum stress is a target for therapy in Waldenstrom macroglobulinemia.

scientific article

Endothelial stress products and coagulation markers in patients with multiple myeloma treated with lenalidomide plus dexamethasone: an observational study ⬇️

scientific article published on December 13, 2012

Engineered nanomedicine for myeloma and bone microenvironment targeting.

scientific article

Eph-B2/ephrin-B2 interaction plays a major role in the adhesion and proliferation of Waldenstrom's macroglobulinemia

scientific article published on 18 October 2011

Epigenetic modifications as key regulators of Waldenstrom's Macroglobulinemia biology

scientific article

Epigenetics in Multiple Myeloma.

scientific article

Epigenetics in Waldenström's macroglobulinemia

scientific article published on 01 October 2010

Epigenomics in Waldenstrom's macroglobulinaemia

scientific article published on June 2016

Established and Novel Prognostic Biomarkers in Multiple Myeloma

scientific article

Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia.

scientific article published on 22 February 2016

Exosomes in Tumor Angiogenesis

scientific article published in January 2016

Experimental design and analysis of antibody microarrays: applying methods from cDNA arrays

scientific article

Expression of regulatory genes for lymphoplasmacytic cell differentiation in Waldenstrom Macroglobulinemia

scientific article published on 06 February 2009

Extramedullary Waldenström macroglobulinemia

scientific article published on 19 November 2014

Extramedullary multiple myeloma

scientific article published on 31 December 2012

FGFR3 Is Overexpressed Waldenström Macroglobulinemia and Its Inhibition by Dovitinib Induces Apoptosis and Overcomes Stroma-Induced Proliferation ⬇️

scientific article (publication date: July 2011)

Fatal coronary artery disease after unrelated donor bone marrow transplantation

scientific article

Finding the right academic job.

scientific article published on January 2009

Fluorescence monitoring of rare circulating tumor cell and cluster dissemination in a multiple myeloma xenograft model in vivo

scientific article published on 01 August 2019

Future Directions in the Evaluation and Treatment of Precursor Plasma Cell Disorders

scientific article published on January 2016

Gene-expression profiling of Waldenstrom macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma

scientific article

Genetic Subtypes of Smoldering Multiple Myeloma are associated with Distinct Pathogenic Phenotypes and Clinical Outcomes

Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes

scientific article published on 01 January 2022

Genome instability in multiple myeloma

scientific article published on 10 July 2020

Genomic Aberrations in Multiple Myeloma

scientific article

Genomic Landscape of Waldenström Macroglobulinemia and Its Impact on Treatment Strategies

scientific article published on 21 February 2020

Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression

scientific article published on 22 May 2020

Genomic complexity of multiple myeloma and its clinical implications

scientific article

Global epigenetic regulation of microRNAs in multiple myeloma

scientific article

Hepatitis C viral infection is not associated with Waldenström's macroglobulinemia.

scientific article published in January 2007

High-dose intravenous methotrexate followed by autologous stem cell transplantation as a potentially effective therapy for neurolymphomatosis

scientific article published on 01 June 2004

High-resolution genomic analysis in Waldenström's macroglobulinemia identifies disease-specific and common abnormalities with marginal zone lymphomas

scientific article (publication date: March 2009)

How I treat smoldering multiple myeloma

scientific article

Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation

scientific article published on 2 November 2017

Hypoxia promotes dissemination and colonization in new bone marrow niches in Waldenström macroglobulinemia

scientific article published on 17 September 2014

Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features ⬇️

scientific article published on March 6, 2012

IL-3 is a potential inhibitor of osteoblast differentiation in multiple myeloma

scientific article

Ibrutinib in previously treated Waldenström's macroglobulinemia.

scientific article

Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-kappaB signaling pathways in Waldenstrom's macroglobulinemia

scientific article (publication date: 15 April 2009)

IgM myeloma: A multicenter retrospective study of 134 patients

scientific article published on 6 April 2017

Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma

Immunotherapy for hematological malignancies

scientific article published on 01 June 2019

Immunotherapy in Multiple Myeloma: Accelerating on the Path to the Patient

scientific article published on 20 February 2019

In Vivo Monitoring of Rare Circulating Tumor Cell and Cluster Dissemination in a Multiple Myeloma Xenograft Model

scientific article published on 11 January 2019

Incidence and clinical features of extramedullary multiple myeloma in patients who underwent stem cell transplantation

scientific article published in April 2015

Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs

scientific article published on 8 December 2008

Inflammatory stromal cells in the myeloma microenvironment

Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma.

scientific article

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma

scientific article

Inhibition of microRNA-138 enhances bone formation in multiple myeloma bone marrow niche

scientific article published on 20 June 2018

Inhibitors of the ras oncogene as therapeutic targets

scientific article

Initial increase in the cryoglobulin level after rituximab therapy for type II cryoglobulinemia secondary to Waldenström macroglobulinemia does not indicate failure of response

scientific article published on 01 December 2004

Integrin β7-mediated regulation of multiple myeloma cell adhesion, migration, and invasion

scientific article published on 7 April 2011

Intensification and consolidation therapy in multiple myeloma in the current era

scientific article published on 30 April 2020

Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model.

scientific article

Key role of microRNAs in Waldenström's macroglobulinemia pathogenesis

scientific article published on 01 February 2011

Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells

article

LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas

scientific article published on 13 July 2012

Lenalidomide in multiple myeloma: an evidence-based review of its role in therapy ⬇️

scientific article published on June 15, 2010

Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma

scientific article

Long-Term Follow-Up of Ibrutinib Monotherapy in Symptomatic, Previously Treated Patients With Waldenström Macroglobulinemia

scientific article published on 15 September 2020

Long-term results of the phase II trial of the oral mTOR inhibitor everolimus (RAD001) in relapsed or refractory Waldenstrom Macroglobulinemia

scientific article

Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group

scientific article

MGUS and smoldering myeloma: the most prevalent of plasma cell dyscrasias

scientific article published on June 1, 2011

Management of Relapsed and Relapsed/Refractory Multiple Myeloma ⬇️

scientific article published on 01 October 2011

Management of myeloma-associated renal dysfunction in the era of novel therapies

scientific article published on February 2012

Management of thalidomide toxicity

scientific article

Managing multiple myeloma: the emerging role of novel therapies and adapting combination treatment for higher risk settings ⬇️

scientific article published on 07 July 2011

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development

scientific article published on 01 December 2020

Mass cytometry staining for human bone marrow clinical samples

Mechanisms of activity of the TORC1 inhibitor everolimus in Waldenstrom macroglobulinemia

scientific article published on 9 October 2012

Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma

scientific article published on April 2007

Metabolic signature identifies novel targets for drug resistance in multiple myeloma

scientific article published on 13 March 2015

Metformin Affects Cortical Bone Mass and Marrow Adiposity in Diet-Induced Obesity in Male Mice.

scientific article

Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration

Mitochondrial metabolism promotes adaptation to proteotoxic stress

scientific article published on 27 May 2019

Molecular mechanisms of effectiveness of novel therapies in multiple myeloma ⬇️

scientific article published on September 17, 2012

Monoclonal Gammopathy of Undetermined Significance (MGUS)-Not So Asymptomatic after All

scientific article published on 12 June 2020

Monoclonal Gammopathy of Undetermined Significance and Smoldering Multiple Myeloma: A Review of the Current Understanding of Epidemiology, Biology, Risk Stratification, and Management of Myeloma Precursor Disease ⬇️

scientific article published on December 5, 2012

Monoclonal gammopathy of undetermined significance

scientific article published on 22 April 2019

Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma

scientific article

Multimodality imaging in amyloidosis ⬇️

scientific article published on April 27, 2012

Multiple Myeloma With Amplification of Chr1q: Therapeutic Opportunity and Challenges

Multiple Myeloma and the immune microenvironment.

scientific article published on 13 February 2017

Multiple myeloma mesenchymal stem cells: characterization, origin, and tumor-promoting effects

scientific article

Multiple myeloma: biology, standard therapy, and transplant therapy

scientific article published on January 2009

Myeloma Cell Dynamics in Response to Treatment Supports a Model of Hierarchical Differentiation and Clonal Evolution.

scientific article

Myeloma as a model for the process of metastasis: implications for therapy ⬇️

scientific article published on April 24, 2012

New frontiers in the treatment of multiple myeloma

scientific article published on 06 December 2006

New insights into the pathogenesis and treatment of Waldenstrom macroglobulinemia.

scientific article published on July 2011

Novel M-component based biomarkers in Waldenström's macroglobulinemia

scientific article published on 01 February 2011

Novel agents in Waldenstrom Macroglobulinemia

scientific article

Novel agents in Waldenström macroglobulinemia.

scientific article

Novel agents in the treatment of Waldenström's macroglobulinemia.

scientific article published on August 2007

Novel therapeutic agents in Waldenström's macroglobulinemia

scientific article

Novel therapeutic avenues in myeloma: changing the treatment paradigm.

scientific article published on June 2007

Novel therapies in the treatment of multiple myeloma

scientific article published on October 2009

Novel treatment options for Waldenström macroglobulinemia

scientific article published on September 2013

Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma

scientific article

Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy ⬇️

scientific article published on January 1, 2011

Outcomes in patients with relapsed or refractory multiple myeloma in a phase I study of everolimus in combination with lenalidomide

scientific article

P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment ⬇️

scientific article published on November 16, 2011

Perifosine Plus Bortezomib and Dexamethasone in Patients With Relapsed/Refractory Multiple Myeloma Previously Treated With Bortezomib: Results of a Multicenter Phase I/II Trial ⬇️

scientific article published on October 11, 2011

Perspectives on the Risk-Stratified Treatment of Multiple Myeloma

Phase 1 study of ibrutinib and the CXCR4 antagonist ulocuplumab in CXCR4-mutated Waldenström macroglobulinemia

Phase 1 study of pomalidomide MTD, safety, and efficacy in patients with refractory multiple myeloma who have received lenalidomide and bortezomib ⬇️

scientific article published on December 14, 2012

Phase I/II trial of the CXCR4 inhibitor plerixafor in combination with bortezomib as a chemosensitization strategy in relapsed/refractory multiple myeloma

scientific article published on 04 October 2019

Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma

scientific article

Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory Waldenstrom macroglobulinemia

scientific article

Phase II trial of weekly bortezomib in combination with rituximab in relapsed or relapsed and refractory Waldenstrom macroglobulinemia

scientific article

Phase II trial of weekly bortezomib in combination with rituximab in untreated patients with Waldenström Macroglobulinemia

scientific article

Platelets enhance Multiple Myeloma progression via IL-1β upregulation

scientific article published on 9 February 2018

Prediagnosis dietary pattern and survival in patients with multiple myeloma

scientific article published on 17 February 2020

Pregnancy outcomes, risk factors, and cell count trends in pregnant women with essential thrombocythemia

scientific article published on 29 September 2020

Prevalence of monoclonal gammopathies and clinical outcomes in a high-risk US population screened by mass spectrometry: a multicentre cohort study

Profiling of circulating exosomal miRNAs in patients with Waldenström Macroglobulinemia

scientific article published in PLoS ONE

Prognostic analysis for survival in adult solid organ transplant recipients with post-transplantation lymphoproliferative disorders.

scientific article published on 26 September 2005

Prognostic factors in patients with post-transplant lymphoproliferative disorders (PTLD) in the rituximab era.

scientific article published in February 2005

Prognostic model for disease-specific and overall mortality in newly diagnosed symptomatic patients with Waldenstrom macroglobulinaemia

scientific article

Prognostic role of circulating exosomal miRNAs in multiple myeloma

scientific article published on 17 February 2017

Progression Risk Stratification of Asymptomatic Waldenström Macroglobulinemia

scientific article published on 16 April 2019

Progression signature underlies clonal evolution and dissemination of multiple myeloma

scientific article published on 04 November 2020

Prospective, Multicenter Clinical Trial of Everolimus as Primary Therapy in Waldenstrom Macroglobulinemia (WMCTG 09-214).

scientific article published on 11 November 2016

Protein kinase C inhibitor enzastaurin induces in vitro and in vivo antitumor activity in Waldenstrom macroglobulinemia

scientific article published on 06 February 2007

Proteomic Analysis of Waldenstrom Macroglobulinemia

article

Proteomic analysis of mantle-cell lymphoma by protein microarray

scientific article published on 13 January 2005

Proteomics analysis in post-transplant lymphoproliferative disorders

scientific article

Pyk2 promotes tumor progression in multiple myeloma

scientific article

Quality of life, psychological distress, and prognostic perceptions in caregivers of patients with multiple myeloma

Quality of life, psychological distress, and prognostic perceptions in patients with multiple myeloma

ROBO1 Promotes Homing, Dissemination, and Survival of Multiple Myeloma within the Bone Marrow Microenvironment

Radioimmunotherapy: a new treatment modality for B-cell non-Hodgkin's lymphoma

scientific article published on May 2004

Regular Aspirin Use and Mortality in Patients with Multiple Myeloma

Regulation of microRNAs in cancer metastasis.

scientific article published on 22 February 2014

Renal cell carcinoma with acrometastasis and scalp metastasis

scientific article published on 01 January 2004

Reply to F.D. Leonard

scientific article published on 19 August 2019

Response assessment in Waldenström macroglobulinaemia: update from the VIth International Workshop

scientific article

Response to ibrutinib in a patient with IgG lymphoplasmacytic lymphoma carrying the MYD88 L265P gene mutation

scientific article published on 16 March 2016

Results of a phase 2 trial of the single-agent histone deacetylase inhibitor panobinostat in patients with relapsed/refractory Waldenström macroglobulinemia ⬇️

scientific article published on January 3, 2013

Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia

scientific article

Review of clinical trials conducted in Waldenstrom macroglobulinemia and recommendations for reporting clinical trial responses in these patients ⬇️

scientific article published on October 1, 2010

Revisiting treatment paradigms in high-risk smoldering multiple myeloma: out with the old, in with the new? ⬇️

scientific article published on May 2, 2013

RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.

scientific article

Role of dual PI3/Akt and mTOR inhibition in Waldenstrom's Macroglobulinemia

scientific article

Role of endothelial progenitor cells in cancer progression

scientific article published on 04 April 2014

Role of microRNAs from monoclonal gammopathy of undetermined significance to multiple myeloma

scientific article published in January 2011

Role of proteasome inhibition in Waldenström's macroglobulinemia.

scientific article published on March 2009

SDF-1 inhibition targets the bone marrow niche for cancer therapy

scientific article published on 25 September 2014

SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia

scientific article

Safety and immunogenicity of conjugate quadrivalent meningococcal vaccination after hematopoietic cell transplantation

scientific article published on 01 June 2018

Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenstrom macroglobulinemia

scientific article published on 28 January 2010

Serum IgM level as predictor of symptomatic hyperviscosity in patients with Waldenström macroglobulinaemia

scientific article

Serum galactomannan and (1->3)-β-D-glucan assays for patients with multiple myeloma and Waldenstrom's macroglobulinemia.

scientific article published on 14 December 2011

Serum immunoglobulin free light chain correlates with tumor burden markers in Waldenstrom macroglobulinemia

scientific article published on 01 June 2008

Single Cell Characterization of Myeloma and its Precursor Conditions Reveals Transcriptional Signatures of Early Tumorigenesis

Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis

Single-Cell Multi-Omics Defines the Cell-Type Specific Impact of <i>SF3B1</i> Splicing Factor Mutations on Hematopoietic Differentiation in Human Clonal Hematopoiesis and Myelodysplastic Syndromes

scientific article published in 2021

Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma

scientific article published on 27 April 2020

Single-cell multi-omics defines the cell-type specific impact of splicing aberrations in human hematopoietic clonal outgrowths

Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation

Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation

Single-cell profiling of tumour evolution in multiple myeloma — opportunities for precision medicine

Stem Cell Implants for Cancer Therapy: TRAIL-Expressing Mesenchymal Stem Cells Target Cancer Cells In Situ

scientific article

TAK-228 (formerly MLN0128), an investigational oral dual TORC1/2 inhibitor: A phase I dose escalation study in patients with relapsed or refractory multiple myeloma, non-Hodgkin lymphoma, or Waldenström's macroglobulinemia

scientific article

Tailoring treatment for multiple myeloma patients with relapsed and refractory disease

scientific article published in March 2010

Targeted therapies in Waldenström macroglobulinemia

scientific article

Targeting Akt and heat shock protein 90 produces synergistic multiple myeloma cell cytotoxicity in the bone marrow microenvironment

scientific article published on February 2008

Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis

scientific article

Targeting NF-kappaB in Waldenstrom macroglobulinemia

scientific article

Targeting SDF-1 in multiple myeloma tumor microenvironment

scientific article

Targeting apoptosis pathways in cancer therapy

scientific article published on 01 May 2005

Targeting survival and cell trafficking in multiple myeloma and Waldenstrom macroglobulinemia using pan-class I PI3K inhibitor, buparlisib

scientific article

Targeting the bone marrow in Waldenstrom macroglobulinemia.

scientific article published on 30 April 2011

Targeting the bone marrow microenvironment in multiple myeloma.

scientific article

Targeting the phosphatidylinositol 3-kinase pathway in multiple myeloma

scientific article published on July 2007

Team work matters: dual inhibition puts non-hodgkin lymphoma under siege

scientific article published on 7 October 2014

Thalidomide derivative CC-4047 inhibits osteoclast formation by down-regulation of PU.1.

scientific article published on 22 December 2005

The 2020 BMT CTN Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia

scientific article (publication date: 15 December 2007)

The BTK-inhibitor ibrutinib may protect against pulmonary injury in COVID-19 infected patients

scientific article published on 17 April 2020

The Bone Marrow Niche in Waldenström's Macroglobulinemia ⬇️

scientific article published on February 1, 2011

The COronavirus Pandemic Epidemiology (COPE) Consortium: A Call to Action

scientific article published on 05 May 2020

The HMG-CoA inhibitor, simvastatin, triggers in vitro anti-tumour effect and decreases IgM secretion in Waldenstrom macroglobulinaemia

scientific article published on 3 June 2008

The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee

The Medical Research Council Myeloma IX trial: the impact on treatment paradigms* ⬇️

scientific article published on November 22, 2011

The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.

scientific article published on April 2017

The Role of Serum Immunoglobulin Free Light Chain in Response and Progression in Waldenstrom Macroglobulinemia ⬇️

scientific article published on March 17, 2011

The Use of Silk as a Scaffold for Mature, Sustainable Unilocular Adipose 3D Tissue Engineered Systems

scientific article published on 19 May 2016

The bone marrow microenvironment in Waldenström macroglobulinemia

scientific article

The bone marrow microenvironment in waldenstrom macroglobulinemia.

scientific article published on August 2011

The bone-marrow niche in MDS and MGUS: implications for AML and MM.

scientific article published on 9 January 2018

The cancer glycome: carbohydrates as mediators of metastasis

scientific article

The emerging importance and evolving understanding of clonal hematopoiesis in multiple myeloma

The importance of the genomic landscape in Waldenström's Macroglobulinemia for targeted therapeutical interventions

scientific article

The microenvironment in myeloma

scientific article published on 01 March 2020

The potential benefits of participating in early‐phase clinical trials in multiple myeloma: long‐term remission in a patient with relapsed multiple myeloma treated with 90 cycles of lenalidomide and bortezomib ⬇️

scientific article published on 07 March 2012

The road to cure in multiple myeloma starts with smoldering disease

scientific article published on April 2015

The role of 18F‐FDG PET/CT imaging in Waldenstrom macroglobulinemia ⬇️

scientific article published on July 1, 2011

The role of miRNAs in plasma cell dyscrasias

scientific article published on 01 January 2014

The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma

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The treatment of multiple myeloma patients not eligible for asct ⬇️

scientific article published on May 3, 2010

The treatment of relapsed and refractory multiple myeloma

scientific article published on January 2007

Therapeutic options in patients with lymphoma and severe liver dysfunction

scientific article published in February 2004

Treatment recommendations for patients with Waldenström macroglobulinemia (WM) and related disorders: IWWM-7 consensus

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Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma

Triply Loaded Nitroxide Brush-Arm Star Polymers Enable Metal-Free Millimetric Tumor Detection by Magnetic Resonance Imaging

scientific article published on 02 November 2018

Tu1677 Upregulation of Fas Ligand Expression Promotes Colon Cancer Cell Migration and Metastasis In Vitro and In Vivo

Update on Waldenström's macroglobulinemia

scientific article published on April 1, 2013

Update on therapeutic options in Waldenström macroglobulinemia

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Update on treatment recommendations from the Fourth International Workshop on Waldenstrom's Macroglobulinemia

scientific article published on December 2008

Waldenstrom macroglobulinemia

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Waldenström macroglobulinaemia.

scientific article published on November 2003

Waldenström macroglobulinemia

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Waldenström macroglobulinemia: from biology to treatment

scientific article published on 03 January 2014

Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study

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Would the real myeloma cell please stand up?

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miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms

miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer.

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microRNA aberrations and their role in supporting hematologic malignancies

scientific article published on 01 January 2014

microRNA aberrations in Waldenström macroglobulinemia

scientific article published on 07 March 2013

microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia

scientific article

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