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List of works by John C Chaput

A Gram-Scale HPLC-Free Synthesis of TNA Triphosphates Using an Iterative Phosphorylation Strategy.

scientific article published on 2 August 2017

A Tool for the Import of Natural and Unnatural Nucleoside Triphosphates into Bacteria.

scientific article published on 17 January 2018

Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway

scientific article published on 19 October 2018

Elucidating the Determinants of Polymerase Specificity by Microfluidic-Based Deep Mutational Scanning

scientific article published on 13 May 2019

Engineering polymerases for applications in synthetic biology

scientific article published on 27 July 2020

Evaluating the Catalytic Potential of a General RNA-Cleaving FANA Enzyme

scientific article published on 06 December 2019

Evaluating the Rate and Substrate Specificity of Laboratory Evolved XNA Polymerases

scientific article

Evolution of a General RNA-Cleaving FANA Enzyme

scientific article published in Nature Communications

Fluorescence-Activated Droplet Sorting for Single-Cell Directed Evolution

scientific article published on 23 May 2019

Following replicative DNA synthesis by time-resolved X-ray crystallography

scientific article published on 11 May 2021

Generating Biologically Stable TNA Aptamers that Function with High Affinity and Thermal Stability

scientific article published on 16 April 2020

In Vitro Selection of an ATP-Binding TNA Aptamer

scientific article published on 13 September 2020

Ligase-Mediated Threose Nucleic Acid Synthesis on DNA Templates

scientific article published on 14 January 2019

Orthogonal Genetic Systems

scientific article published on 30 December 2019

P(V) Reagents for the Scalable Synthesis of Natural and Modified Nucleoside Triphosphates

scientific article published on 13 August 2019

RNA-Catalyzed Polymerization of Deoxyribose, Threose, and Arabinose Nucleic Acids

scientific article published on 03 May 2019

Structural basis for TNA synthesis by an engineered TNA polymerase

scientific article published on 27 November 2017

Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7-Deaza-7-Substituted Guanosine Residues

scientific article published on 23 April 2018

Synthesis of 2'-Deoxy-α-l-threofuranosyl Nucleoside Triphosphates

scientific article published on 27 July 2018

Synthesis of α-l-Threofuranosyl Nucleoside 3'-Monophosphates, 3'-Phosphoro(2-Methyl)imidazolides, and 3'-Triphosphates.

scientific article

Visualizing primer extension without enzymes.

scientific article

What Is XNA?

scientific article published on 19 July 2019

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