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List of works by Lars Dölken

4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response

scientific article

A spread-deficient cytomegalovirus for assessment of first-target cells in vaccination

scientific article

Age-dependent prevalence and frequency of circulating t(14;18)-positive cells in the peripheral blood of healthy individuals.

scientific article

All for one and one for all: herpesviral microRNAs close in on their prey.

scientific article published in April 2009

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway

scientific article

Biodistribution and serologic response in SARS-CoV-2 induced ARDS: A cohort study

scientific article published on 24 November 2020

CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response

scientific article

Conserved principles of mammalian transcriptional regulation revealed by RNA half-life

scientific article published on 26 June 2009

Cytomegalovirus microRNAs

scientific article published on 17 March 2009

Cytomegalovirus microRNAs facilitate persistent virus infection in salivary glands

scientific article

Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis.

scientific article published on 05 July 2013

Degradation of cellular mir-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo

scientific article

Dissecting Herpes Simplex Virus 1-Induced Host Shutoff at the RNA Level

scientific article published on 04 November 2020

Dissecting newly transcribed and old RNA using GRAND-SLAM.

scientific article published in July 2018

Dominant negative mutants of the murine cytomegalovirus M53 gene block nuclear egress and inhibit capsid maturation.

scientific article published on 7 July 2010

Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast ⬇️

scientific article published on January 4, 2011

Effects of Prednisolone on Disease Progression in Antiretroviral-Untreated HIV Infection: A 2-Year Randomized, Double-Blind Placebo-Controlled Clinical Trial

scientific article published on 26 January 2016

Frequency of BCL-2/J(H) translocation in healthy males exposed to low-level radiation in comparison to age-matched health controls

scientific article published on 01 August 2002

Genome-wide survey of interindividual differences of RNA stability in human lymphoblastoid cell lines

scientific article published on January 2013

HALO--a Java framework for precise transcript half-life determination.

scientific article

HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes.

scientific article published on 26 March 2018

Herpes simplex virus blocks host transcription termination via the bimodal activities of ICP27

scientific article published on 15 January 2020

High resolution gene expression profiling of RNA synthesis, processing, and decay by metabolic labeling of newly transcribed RNA using 4-thiouridine

scientific article published in January 2013

High-Resolution Gene Expression Profiling of RNA Synthesis, Processing, and Decay by Metabolic Labeling of Newly Transcribed RNA Using 4-Thiouridine

scientific article published on January 2017

High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay

scientific article published on 24 July 2008

Human cytomegalovirus disrupts the major histocompatibility complex class I peptide-loading complex and inhibits tapasin gene transcription

scientific article published on 19 January 2011

Identification of the cryptic HLA-I immunopeptidome

scientific article published on 19 June 2020

Improved Ribo-seq enables identification of cryptic translation events.

scientific article published on 12 March 2018

Inactivation of intergenic enhancers by EBNA3A initiates and maintains polycomb signatures across a chromatin domain encoding CXCL10 and CXCL9

scientific article

Integrative functional genomics decodes herpes simplex virus 1

scientific article published on 27 April 2020

Low prevalence of circulating t(11;14)(q13;q32)-positive cells in the peripheral blood of healthy individuals as detected by real-time quantitative PCR.

scientific article

Lymph Node Macrophages Restrict Murine Cytomegalovirus Dissemination

scientific article published on 29 April 2015

Metabolic labeling of newly transcribed RNA for high resolution gene expression profiling of RNA synthesis, processing and decay in cell culture

scientific article published on 8 August 2013

Metabolic tagging and purification of nascent RNA: implications for transcriptomics.

scientific article published on 26 August 2009

Mouse cytomegalovirus microRNAs dominate the cellular small RNA profile during lytic infection and show features of posttranscriptional regulation

scientific article

Murine cytomegalovirus virion-associated protein M45 mediates rapid NF-κB activation after infection

scientific article published on 18 June 2014

Natural killer cells are required for extramedullary hematopoiesis following murine cytomegalovirus infection.

scientific article published in May 2013

Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions.

scientific article published on 24 May 2013

P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress

scientific article published on 26 February 2019

PARma: identification of microRNA target sites in AGO-PAR-CLIP data ⬇️

scientific article

Piscine Orthoreovirus 3 Is Not the Causative Pathogen of Proliferative Darkening Syndrome (PDS) of Brown Trout ()

scientific article published on 28 January 2019

Post-transcriptional regulation of miR-27 in murine cytomegalovirus infection

scientific article

Prevalence and frequency of circulating t(14;18)-MBR translocation carrying cells in healthy individuals

scientific article

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway

scientific article published on 14 July 2015

RIP-chip enrichment analysis

scientific article

RNA dynamics revealed by metabolic RNA labeling and biochemical nucleoside conversions.

scientific article

Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection

scientific article

Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency.

scientific article

Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis

scientific article published on 15 October 2019

Shedding light on the elusive role of endothelial cells in cytomegalovirus dissemination.

scientific article

Small RNA deep sequencing identifies microRNAs and other small noncoding RNAs from human herpesvirus 6B

scientific article

Small RNAs growing tall: miRNAs as drug targets in herpesvirus infections

scientific article published on 05 August 2015

Small noncoding RNA: novel targets for antiviral therapy

scientific article published in December 2008

Synthesis and decay of varicella zoster virus transcripts ⬇️

scientific article published on April 12, 2011

Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay

scientific article published on April 2010

The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment

scientific article published on 31 July 2020

The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors

scientific article published on 29 May 2019

The miRNA-targetome of KSHV and EBV in human B-cells

scientific article published in January 2011

The phosphoproteome of toll-like receptor-activated macrophages

scientific article published on June 2010

Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution

scientific article

Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection.

scientific article published on 31 October 2017

Widespread context dependency of microRNA-mediated regulation

scientific article published on 25 March 2014

Widespread disruption of host transcription termination in HSV-1 infection.

scientific article published on 20 May 2015

scSLAM-seq reveals core features of transcription dynamics in single cells

scientific article published on 10 July 2019

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