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List of works by Xiang-Jin Meng

A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection

scientific article published in January 2013

A chimeric virus created by DNA shuffling of the capsid genes of different subtypes of porcine circovirus type 2 (PCV2) in the backbone of the non-pathogenic PCV1 induces protective immunity against the predominant PCV2b and the emerging PCV2d in pi

scientific article published on 23 August 2016

A dual vaccine candidate against norovirus and hepatitis E virus

scientific article published on 27 November 2013

A live-attenuated and an inactivated chimeric porcine circovirus (PCV)1-2 vaccine are both effective at inducing a humoral immune response and reducing PCV2 viremia and intrauterine infection in female swine of breeding age.

scientific article published on January 2014

A novel pathogenic Mammalian orthoreovirus from diarrheic pigs and Swine blood meal in the United States

scientific article published on 19 May 2015

A novel virus in swine is closely related to the human hepatitis E virus ⬇️

scientific article published on September 2, 1997

A trivalent vaccine candidate against hepatitis E virus, norovirus, and astrovirus

scientific article published on 8 January 2016

Amino acid residues Ala283 and His421 in the RNA-dependent RNA polymerase of porcine reproductive and respiratory syndrome virus play important roles in viral ribavirin sensitivity and quasispecies diversity

scientific article published on 19 October 2015

An SH3 binding motif within the nucleocapsid protein of porcine reproductive and respiratory syndrome virus interacts with the host cellular signaling proteins STAMI, TXK, Fyn, Hck, and cortactin

scientific article published on 13 April 2015

An experimental live chimeric porcine circovirus 1-2a vaccine decreases porcine circovirus 2b viremia when administered intramuscularly or orally in a porcine circovirus 2b and porcine reproductive and respiratory syndrome virus dual-challenge model

scientific article published in December 2011

Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs

scientific article

Attenuation of Porcine Reproductive and Respiratory Syndrome Virus by Molecular Breeding of Virus Envelope Genes from Genetically Divergent Strains ⬇️

scientific article published on October 17, 2012

Branched-linear and agglomerate protein polymers as vaccine platforms

scientific article

Broadening the heterologous cross-neutralizing antibody inducing ability of porcine reproductive and respiratory syndrome virus by breeding the GP4 or M genes.

scientific article

CD8+ lymphocytes but not B lymphocytes are required for protection against chronic hepatitis E virus infection in chickens

scientific article published on 25 July 2019

Characterization of shedding patterns of Porcine circovirus types 2a and 2b in experimentally inoculated mature boars.

scientific article

Chimeric Porcine Circoviruses (PCV) Containing Amino Acid Epitope Tags in the C Terminus of the Capsid Gene Are Infectious and Elicit both Anti-Epitope Tag Antibodies and Anti-PCV Type 2 Neutralizing Antibodies in Pigs ⬇️

scientific article published on February 9, 2011

Chimeric porcine reproductive and respiratory syndrome virus containing shuffled multiple envelope genes confers cross-protection in pigs

scientific article published on 2 September 2015

Comparison of 12 turkey hemorrhagic enteritis virus isolates allows prediction of genetic factors affecting virulence

scientific article

Comparison of commercial enzyme-linked immunosorbent assays and fluorescent microbead immunoassays for detection of antibodies against porcine reproductive and respiratory syndrome virus in boars.

scientific article published on 19 December 2013

Comparison of commercial real-time reverse transcription-PCR assays for reliable, early, and rapid detection of heterologous strains of porcine reproductive and respiratory syndrome virus in experimentally infected or noninfected boars by use of dif

scientific article published on 5 December 2012

Comparison of real-time reverse transcriptase PCR assays for detection of swine hepatitis E virus in fecal samples

scientific article published on 15 January 2014

Comparison of the effectiveness of passive (dam) versus active (piglet) immunization against porcine circovirus type 2 (PCV2) and impact of passively derived PCV2 vaccine-induced immunity on vaccination

scientific article published on 12 November 2009

Comparison of three enzyme-linked immunosorbent assays to detect Porcine circovirus-2 (PCV-2)-specific antibodies after vaccination or inoculation of pigs with distinct PCV-1 or PCV-2 isolates

scientific article published on 01 November 2008

Complete genome sequence of hepatitis E virus from rabbits in the United States

scientific article

Computer-aided codon-pairs deoptimization of the major envelope GP5 gene attenuates porcine reproductive and respiratory syndrome virus

scientific article published on 31 December 2013

Concurrent porcine circovirus type 2a (PCV2a) or PCV2b infection increases the rate of amino acid mutations of porcine reproductive and respiratory syndrome virus (PRRSV) during serial passages in pigs.

scientific article published on 13 September 2013

Consensus proposals for classification of the family Hepeviridae

scientific article published on 01 May 2015

Consensus proposals for classification of the family Hepeviridae

scientific article

Construction and efficacy evaluation of novel swine leukocyte antigen (SLA) class I and class II allele-specific poly-T cell epitope vaccines against porcine reproductive and respiratory syndrome virus

scientific article published on 07 September 2020

Construction of an infectious cDNA clone of avian hepatitis E virus (avian HEV) recovered from a clinically healthy chicken in the United States and characterization of its pathogenicity in specific-pathogen-free chickens.

scientific article

Construction of an infectious cDNA clone of genotype 1 avian hepatitis E virus: characterization of its pathogenicity in broiler breeders and demonstration of its utility in studying the role of the hypervariable region in virus replication

scientific article published on 15 January 2015

Cross-species infection of pigs with a novel rabbit, but not rat, strain of hepatitis E virus isolated in the United States ⬇️

scientific article published on April 25, 2012

Cytotoxic T lymphocyte epitopes identified from a contemporary strain of porcine reproductive and respiratory syndrome virus enhance CD4+CD8+ T, CD8+ T, and γδ T cell responses

scientific article published on 17 September 2019

DNA shuffling of the GP3 genes of porcine reproductive and respiratory syndrome virus (PRRSV) produces a chimeric virus with an improved cross-neutralizing ability against a heterologous PRRSV strain

scientific article

Dendritic cell-targeted porcine reproductive and respiratory syndrome virus (PRRSV) antigens adjuvanted with polyinosinic-polycytidylic acid (poly (I:C)) induced non-protective immune responses against heterologous type 2 PRRSV challenge in pigs

scientific article published on 10 July 2017

Development and evaluation of two subunit vaccine candidates containing antigens of hepatitis E virus, rotavirus, and astrovirus

scientific article published on 19 May 2016

Development of a fluorescent microbead-based immunoassay for the detection of hepatitis E virus IgG antibodies in pigs and comparison to an enzyme-linked immunoassay

scientific article published on 14 June 2013

Dissecting the potential role of hepatitis E virus ORF1 non-structural gene in cross-species infection by using intergenotypic chimeric viruses

scientific article published on 26 June 2020

Effect of porcine circovirus type 2a or 2b on infection kinetics and pathogenicity of two genetically divergent strains of porcine reproductive and respiratory syndrome virus in the conventional pig model

scientific article published on 17 February 2012

Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2) ⬇️

scientific article published on 07 October 2011

Efficient priming of CD4 T cells by Langerin-expressing dendritic cells targeted with porcine epidemic diarrhea virus spike protein domains in pigs

scientific article

Enhancing heterologous protection in pigs vaccinated with chimeric porcine reproductive and respiratory syndrome virus containing the full-length sequences of shuffled structural genes of multiple heterologous strains.

scientific article published on 23 March 2017

Establishment of a DNA-launched infectious clone for a highly pneumovirulent strain of type 2 porcine reproductive and respiratory syndrome virus: identification and in vitro and in vivo characterization of a large spontaneous deletion in the nsp2 r

scientific article

Evaluation of the pathogenicity of mammalian orthoreovirus type 3 (MRV3) in germ-free gnotobiotic pigs and of the efficacy of an inactivated vaccine against MRV3 infection in neonatal conventional piglets

scientific article published on 22 August 2018

Evaluation of the use of non-pathogenic porcine circovirus type 1 as a vaccine delivery virus vector to express antigenic epitopes of porcine reproductive and respiratory syndrome virus

scientific article

Evidence for an Unknown Agent Antigenically Related to the Hepatitis E Virus in Dairy Cows in the United States

article

Expanding Host Range and Cross-Species Infection of Hepatitis E Virus

scientific article

Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV ⬇️

scientific article published on January 1, 1998

Experimental infection of pregnant gilts with swine hepatitis E virus ⬇️

scientific article published on October 1, 2003

Expression of antigenic epitopes of porcine reproductive and respiratory syndrome virus (PRRSV) in a modified live-attenuated porcine circovirus type 2 (PCV2) vaccine virus (PCV1-2a) as a potential bivalent vaccine against both PCV2 and PRRSV.

scientific article

Expression of human CD46 has no effect on porcine circovirus type 2 infection and shedding in the experimental pig model ⬇️

scientific article published on 03 March 2012

Hepatitis E Virus in Rabbits, Virginia, USA ⬇️

scientific article published on November 1, 2011

Hepatitis E virus: foodborne, waterborne and zoonotic transmission

scientific article published on 25 September 2013

Hepatitis Virus Infections in Poultry

scientific article published on September 2016

ISG15 Modulates Type I Interferon Signaling and the Antiviral Response during Hepatitis E Virus Replication

scientific article

Identification and fine mapping of nuclear and nucleolar localization signals within the human ribosomal protein S17.

scientific article published on 8 April 2015

Immunogenicity and Pathogenicity of Chimeric Infectious DNA Clones of Pathogenic Porcine Circovirus Type 2 (PCV2) and Nonpathogenic PCV1 in Weanling Pigs ⬇️

scientific article published on October 1, 2003

In vivo targeting of porcine reproductive and respiratory syndrome virus antigen through porcine DC-SIGN to dendritic cells elicits antigen-specific CD4T cell immunity in pigs

scientific article published on 18 October 2014

Inactivated and subunit vaccines against porcine reproductive and respiratory syndrome: Current status and future direction

scientific article published on 14 May 2015

Increased frequency of porcine epidemic diarrhea virus shedding and lesions in suckling pigs compared to nursery pigs and protective immunity in nursery pigs after homologous re-challenge

scientific article

Infection dynamics of hepatitis E virus in wild-type and immunoglobulin heavy chain knockout J (-/-) gnotobiotic piglets

scientific article published on 12 October 2018

Infectivity of porcine circovirus type 2 DNA in semen from experimentally-infected boars

scientific article published on 31 October 2008

Inhibition of hepatitis E virus replication by peptide-conjugated morpholino oligomers.

scientific article published on 15 June 2015

Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer ⬇️

scientific article published on April 30, 2011

Intergenotypic chimeric hepatitis E viruses (HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs

scientific article

Interlaboratory comparison of Porcine circovirus-2 indirect immunofluorescent antibody test and enzyme-linked immunosorbent assay results on experimentally infected pigs

scientific article published on 01 March 2011

Isolation of Peripheral Blood CD8 T Cells Specific to Porcine Reproductive and Respiratory Syndrome Virus Utilizing Porcine CD137 Activation Marker.

scientific article

Limited susceptibility of three different mouse (Mus musculus) lines to Porcine circovirus-2 infection and associated lesions

scientific article published in April 2009

Live porcine reproductive and respiratory syndrome virus vaccines: Current status and future direction

scientific article

Markedly different immune responses and virus kinetics in littermates infected with porcine circovirus type 2 or porcine parvovirus type 1.

scientific article published on 9 August 2017

Modulation of Proinflammatory Cytokines in Monocyte-Derived Dendritic Cells by Porcine Reproductive and Respiratory Syndrome Virus Through Interaction with the Porcine Intercellular-Adhesion-Molecule-3-Grabbing Nonintegrin

scientific article published on 19 September 2016

Mutant USA strain of porcine circovirus type 2 (mPCV2) exhibits similar virulence to the classical PCV2a and PCV2b strains in caesarean-derived, colostrum-deprived pigs

scientific article

Mutational analysis of the hypervariable region of hepatitis e virus reveals its involvement in the efficiency of viral RNA replication

scientific article

Naturally occurring animal models of human hepatitis E virus infection

scientific article

Novel chimeric porcine circovirus (PCV) with the capsid gene of the emerging PCV2b subtype cloned in the genomic backbone of the non-pathogenic PCV1 is attenuated in vivo and induces protective and cross-protective immunity against PCV2b and PCV2a s

scientific article published on October 31, 2010

ORF1 but not ORF2 dependent differences are important for in vitro replication of PCV2 in porcine alveolar macrophages singularly or coinfected with PRRSV

scientific article published on 17 February 2012

Origin, evolution, and genotyping of emergent porcine epidemic diarrhea virus strains in the United States

scientific article published on 15 October 2013

Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication

scientific article published on 4 October 2007

Pig model mimicking chronic hepatitis E virus infection in immunocompromised patients to assess immune correlates during chronicity

scientific article published on 19 June 2017

Porcine circovirus type 2 (PCV2)-infection and re-inoculation with homologous or heterologous strains: virological, serological, pathological and clinical effects in growing pigs

scientific article published on 18 January 2010

Porcine circovirus type 2 associated disease: update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies

scientific article

Porcine circovirus type 2 in muscle and bone marrow is infectious and transmissible to naïve pigs by oral consumption

scientific article published on 04 July 2008

Porcine circoviruses: a minuscule yet mammoth paradox.

scientific article published on 02 September 2008

Prior infection of pigs with a genotype 3 swine hepatitis E virus (HEV) protects against subsequent challenges with homologous and heterologous genotypes 3 and 4 human HEV

scientific article

Productive infection of human hepatocellular carcinoma cells by porcine circovirus type 1 ⬇️

scientific article published on July 8, 2011

Proposed reference sequences for hepatitis E virus subtypes.

scientific article published on 7 January 2016

Protective efficacy of a virus-vectored multi-component vaccine against porcine reproductive and respiratory syndrome virus, porcine circovirus type 2 and swine influenza virus

scientific article published in November 2017

RNA transcripts of full-length cDNA clones of rabbit hepatitis E virus are infectious in rabbits

scientific article published on 7 November 2014

Recombinant porcine reproductive and respiratory syndrome virus expressing membrane-bound IL-15 as immunomodulatory adjuvant enhances NK and γδ T cell responses and confers heterologous protection

scientific article published on 11 April 2018

Replacement of the hepatitis E virus ORF3 protein PxxP motif with heterologous late domain motifs affects virus release via interaction with TSG101

scientific article

Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs.

scientific article published on 25 July 2012

Rescue of a porcine anellovirus (torque teno sus virus 2) from cloned genomic DNA in pigs.

scientific article

Restricted enzooticity of hepatitis E virus genotypes 1 to 4 in the United States

scientific article published on 12 October 2011

Risk factors and sources of foodborne hepatitis E virus infection in the United States

scientific article

Roles of the genomic sequence surrounding the stem-loop structure in the junction region including the 3' terminus of open reading frame 1 in hepatitis E virus replication

scientific article published on 25 May 2018

Sequence analysis of open reading frames (ORFs) 2 to 4 of a U.S. isolate of porcine reproductive and respiratory syndrome virus ⬇️

scientific article published on January 1, 1995

Serological Evidence for a Hepatitis E Virus-Related Agent in Goats in the United States ⬇️

scientific article published on August 22, 2012

Serological prevalence, genetic identification, and characterization of the first strains of avian hepatitis E virus from chickens in Korea ⬇️

scientific article published on May 26, 2012

Serological profile of torque teno sus virus species 1 (TTSuV1) in pigs and antigenic relationships between two TTSuV1 genotypes (1a and 1b), between two species (TTSuV1 and -2), and between porcine and human anelloviruses.

scientific article

Subclinical avian hepatitis E virus infection in layer flocks in the United States.

scientific article published on 22 October 2015

Substitution of amino acid residue V1213 in the helicase domain of the genotype 3 hepatitis E virus reduces virus replication.

scientific article published on 8 February 2018

Suppression of porcine reproductive and respiratory syndrome virus replication by morpholino antisense oligomers.

scientific article published on 12 July 2006

Ten years of PCV2 vaccines and vaccination: Is eradication a possibility?

scientific article published on 13 October 2016

The PSAP motif within the ORF3 protein of an avian strain of the hepatitis E virus is not critical for viral infectivity in vivo but plays a role in virus release.

scientific article published on 21 March 2012

The lysine residues within the human ribosomal protein S17 sequence naturally inserted into the viral nonstructural protein of a unique strain of hepatitis E virus are important for enhanced virus replication

scientific article

The non-structural protein Nsp2TF of porcine reproductive and respiratory syndrome virus down-regulates the expression of Swine Leukocyte Antigen class I.

scientific article

The nucleotides on the stem-loop RNA structure in the junction region of the hepatitis E virus genome are critical for virus replication.

scientific article

The prevalence of Torque teno sus virus (TTSuV) is common and increases with the age of growing pigs in the United States.

scientific article published on 31 March 2012

Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation

scientific article

Use of PCR-based assays for the detection of the adventitious agent porcine circovirus type 1 (PCV1) in vaccines, and for confirming the identity of cell substrates and viruses used in vaccine production.

scientific article published on 3 November 2011

Use of heteroduplex mobility assays (HMA) for pre-sequencing screening and identification of variant strains of swine and avian hepatitis E viruses ⬇️

scientific article published on October 17, 2003

Vaccination of sows with a dendritic cell-targeted porcine epidemic diarrhea virus S1 protein-based candidate vaccine reduced viral shedding but exacerbated gross pathological lesions in suckling neonatal piglets

scientific article published on 4 January 2018

Virome of US bovine calf serum

scientific article

Virus-like particle vaccine with B-cell epitope from porcine epidemic diarrhea virus (PEDV) incorporated into hepatitis B virus core capsid provides clinical alleviation against PEDV in neonatal piglets through lactogenic immunity

scientific article published on 18 June 2020

Zoonotic hepatitis E: animal reservoirs and emerging risks

scientific article

Zoonotic origin of hepatitis E.

scientific article

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