Search filters

List of works by Kinichi Nakashima

A small modulatory dsRNA specifies the fate of adult neural stem cells

scientific article

Astrocyte differentiation of neural precursor cells is enhanced by retinoic acid through a change in epigenetic modification.

scientific article published in November 2009

Astrocyte-specific genes are generally demethylated in neural precursor cells prior to astrocytic differentiation

scientific article

BMP-induced REST regulates the establishment and maintenance of astrocytic identity

scientific article published on 29 March 2010

Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells

scientific article published on 16 April 2007

Bidirectional communication between the innate immune and nervous systems for homeostatic neurogenesis in the adult hippocampus

scientific article published on 25 November 2015

Bidirectional promoters are the major source of gene activation-associated non-coding RNAs in mammals

scientific article published on 17 January 2014

Bidirectional promoters link cAMP signaling with irreversible differentiation through promoter-associated non-coding RNA (pancRNA) expression in PC12 cells.

scientific article published on 04 March 2016

Canonical TGF-β signaling negatively regulates neuronal morphogenesis through TGIF/Smad complex-mediated CRMP2 suppression.

scientific article published on 25 April 2018

Cardiotrophin-like cytokine induces astrocyte differentiation of fetal neuroepithelial cells via activation of STAT3

scientific journal article

Cell fusion-independent differentiation of neural stem cells to the endothelial lineage.

scientific article published in July 2004

Characterization of Np95 expression in mouse brain from embryo to adult: A novel marker for proliferating neural stem/precursor cells

scientific article

Chromatin accessibility at a STAT3 target site is altered prior to astrocyte differentiation.

scientific article

Chromatin remodeling in neural stem cell differentiation

scientific article published on 29 April 2010

Committed neuronal precursors confer astrocytic potential on residual neural precursor cells.

scientific article published in February 2009

DNA Methylome Analysis Identifies Transcription Factor-Based Epigenomic Signatures of Multilineage Competence in Neural Stem/Progenitor Cells

scientific article published in September 2017

DNA Methyltransferase 1 Is Indispensable for Development of the Hippocampal Dentate Gyrus

scientific article

Detection of Bidirectional Promoter-Derived lncRNAs from Small-Scale Samples Using Pre-Amplification-Free Directional RNA-seq Method

scientific article

Development of functional human embryonic stem cell-derived neurons in mouse brain

scientific article

Developmental stage dependent regulation of DNA methylation and chromatin modification in a immature astrocyte specific gene promoter.

scientific article

Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage

scientific article published on 27 May 2015

Ectopic neurogenesis induced by prenatal antiepileptic drug exposure augments seizure susceptibility in adult mice.

scientific article published on 2 April 2018

Embryonic stem cells: staying plastic on plastic

scientific article published on 01 January 2004

Enhanced gene activation by Notch and BMP signaling cross-talk ⬇️

scientific article published on October 1, 2003

Enhanced processivity of Dnmt1 by monoubiquitinated histone H3

scientific article published on 03 December 2019

Epigenetic mechanisms in sequential differentiation of neural stem cells.

scientific article published on 18 February 2009

Epigenetic mechanisms regulating differentiation of neural stem/precursor cells

scientific article published on January 2014

Epigenetic mechanisms regulating fate specification of neural stem cells.

scientific article published on June 2008

Epigenetic modulation of seizure-induced neurogenesis and cognitive decline.

scientific article

Epigenetic regulation in neural stem cell differentiation

scientific article

Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain

scholarly article

Epigenetic regulation of neural stem cell differentiation towards spinal cord regeneration

scientific article

Epigenetic regulation of neural stem cell fate during corticogenesis

scientific article

Epigenetic setting and reprogramming for neural cell fate determination and differentiation

scientific article

Evolutionary acquisition of promoter-associated non-coding RNA (pancRNA) repertoires diversifies species-dependent gene activation mechanisms in mammals.

scientific article

Expression and function of orphan nuclear receptor TLX in adult neural stem cells

scientific journal article

Expression of DNMT1 in neural stem/precursor cells is critical for survival of newly generated neurons in the adult hippocampus.

scientific article published on 4 February 2015

Fate redirection of hippocampal astrocytes toward neuronal lineage by aggregate culture.

scientific article

Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation

scientific article published on February 2014

Gene activation-associated long noncoding RNAs function in mouse preimplantation development.

scientific article

Growth factors with valproic acid restore injury-impaired hearing by promoting neuronal regeneration

scientific article published in 2021

HMGB2 expression is associated with transition from a quiescent to an activated state of adult neural stem cells.

scientific article published on 2 August 2017

Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells

scholarly article

Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells

scientific article published on June 2017

IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes

scientific article

Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation

scientific article published on June 2006

Identification of genes associated with the astrocyte-specific gene Gfap during astrocyte differentiation

scientific article

Induction of superficial cortical layer neurons from mouse embryonic stem cells by valproic acid

scientific article published on 6 October 2011

Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb

scientific article

Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures ⬇️

scientific article published on June 1, 2003

L1 retrotransposition in neurons is modulated by MeCP2 ⬇️

scientific article published on November 18, 2010

Low-cost three-dimensional gait analysis system for mice with an infrared depth sensor

scientific article published on 9 July 2015

Maintenance of embryonic stem cell pluripotency by Nanog-mediated reversal of mesoderm specification

scientific article published on 01 March 2006

Manipulation of Promoter-Associated Noncoding RNAs in Mouse Early Embryos for Controlling Sequence-Specific Epigenetic Status

scientific article published in January 2017

Mechanisms of astrocytogenesis in the mammalian brain.

scientific article published on July 2013

Methyl-CpG binding proteins are involved in restricting differentiation plasticity in neurons

scientific journal article

Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function ⬇️

scientific article published on May 14, 2003

MicroRNA-214 Promotes Dendritic Development by Targeting the Schizophrenia-associated Gene Quaking (Qki).

scientific article published on 28 April 2016

NEUROD1 Instructs Neuronal Conversion in Non-Reactive Astrocytes

scientific article

Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells

scientific journal article

Natural and forced neurogenesis in the adult brain: mechanisms and their possible application to treat neurological disorders

scientific article published on 01 June 2020

Neural stem cell therapy aiming at better functional recovery after spinal cord injury.

scientific article published on 2 August 2017

Neuronal differentiation of neural precursor cells is promoted by the methyl-CpG-binding protein MeCP2.

scientific article

Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury.

scientific article

Neuropoietin induces neuroepithelial cells to differentiate into astrocytes via activation of STAT3.

scientific article published in October 2006

Nox4 Promotes Neural Stem/Precursor Cell Proliferation and Neurogenesis in the Hippocampus and Restores Memory Function Following Trimethyltin-Induced Injury

scientific article published on 05 December 2018

Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain

scientific article published on 31 May 2018

Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain

scientific journal article

Oxygen levels epigenetically regulate fate switching of neural precursor cells via hypoxia-inducible factor 1α-notch signal interaction in the developing brain

scientific article

Periventricular notch activation and asymmetric Ngn2 and Tbr2 expression in pair-generated neocortical daughter cells

scientific article

Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion

scientific article published on 09 January 2019

Potentiation of astrogliogenesis by STAT3-mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells

scientific article published on 23 April 2007

Prenatal deletion of DNA methyltransferase 1 in neural stem cells impairs neurogenesis and causes anxiety-like behavior in adulthood

scientific article published on 9 September 2016

Prenatal exposure to suberoylanilide hydroxamic acid perturbs corticogenesis

scientific article

Prior Treatment with Anti-High Mobility Group Box-1 Antibody Boosts Human Neural Stem Cell Transplantation-Mediated Functional Recovery After Spinal Cord Injury.

scientific article published on 8 March 2018

Reconstitution in vitro of the entire cycle of the mouse female germ line

scientific article published on 17 October 2016

Reconstruction of injured spinal cord by epigenetic regulation of transplanted neural stem cells

scientific article published on 9 February 2012

Reduced Adult Hippocampal Neurogenesis and Cognitive Impairments following Prenatal Treatment of the Antiepileptic Drug Valproic Acid

scientific article published on 19 November 2015

Regulation of Adult Mammalian Neural Stem Cells and Neurogenesis by Cell Extrinsic and Intrinsic Factors

scientific article published in 2021

Requirement of gp130 signaling for the AGM hematopoiesis ⬇️

scientific article published on April 1, 2003

Role of GLI2 in the growth of human osteosarcoma.

scientific article published on 19 April 2011

Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus

scientific article

SoxE group transcription factor Sox8 promotes astrocytic differentiation of neural stem/precursor cells downstream of Nfia

scientific article published on 01 December 2021

Stage- and site-specific DNA demethylation during neural cell development from embryonic stem cells.

scientific article published in April 2005

Synergistic induction of astrocytic differentiation by factors secreted from meninges in the mouse developing brain

scientific article

TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus

scientific article published on 9 March 2015

Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions

scientific article

The NRSE smRNA specifies the fate of adult hippocampal neural stem cells

scientific article published in January 2005

The Role of gp130 in cerebral cortical development: in vivo functional analysis in a mouse exo utero system.

scientific article published in July 2002

Therapeutic time window of anti-high mobility group box-1 antibody administration in mouse model of spinal cord injury.

scientific article published on 28 March 2018

Treatment of a mouse model of spinal cord injury by transplantation of human induced pluripotent stem cell-derived long-term self-renewing neuroepithelial-like stem cells

scientific article published in June 2012

Treatment of spinal cord injury by transplantation of fetal neural precursor cells engineered to express BMP inhibitor

scientific article published in September 2004

Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation

scientific article published in Nature Communications

VPA alleviates neurological deficits and restores gene expression in a mouse model of Rett syndrome

scientific article (publication date: 2014)

Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis.

scientific article published on 23 August 2009

[Epigenetic mechanisms regulating neural cell fate determination]

scientific article published on 01 November 2009

[Epigenetic regulation involved in fate specification of neural cells]

scientific article published on 01 March 2008

[Epigenetic regulation of neural stem cell fate specification]

scientific article published on 01 February 2008

[Novel function of MeCP2 in the pathophysiology of Rett syndrome: Regulation of mTOR signaling mediated by MeCP2-dependent microRNA processing]

article published in 2017

miR-199a Links MeCP2 with mTOR Signaling and Its Dysregulation Leads to Rett Syndrome Phenotypes.

scientific article published on 2 September 2015

Paulina is supported by:

About Paulina

Help