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List of works by Johan Trygg

A cross-species transcriptomics approach to identify genes involved in leaf development

scientific article

A geographically matched control population efficiently limits the number of candidate disease-causing variants in an unbiased whole-genome analysis

scientific article published on 27 March 2019

A multi-omics approach reveals function of Secretory Carrier-Associated Membrane Proteins in wood formation of Populus trees.

scientific article published on 3 January 2018

A statistical resampling method to calculate biomagnification factors exemplified with organochlorine data from herring (Clupea harengus) muscle and guillemot (Uria aalge) egg from the Baltic sea.

scientific article

A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences

scientific article published on 11 September 2020

ADC texture--an imaging biomarker for high-grade glioma?

scientific article published in October 2014

Altered metabolic signature in pre-diabetic NOD mice.

scientific article published on 13 April 2012

Building Multivariate Systems Biology Models

scientific article published on August 2, 2012

CV-ANOVA for significance testing of PLS and OPLS® models

scientific article published in 2008

Cell-specific chemotyping and multivariate imaging by combined FT-IR microspectroscopy and orthogonal projections to latent structures (OPLS) analysis reveals the chemical landscape of secondary xylem

scientific article

Changes in diurnal patterns within the Populus transcriptome and metabolome in response to photoperiod variation

scientific article published on 18 March 2010

Chemometrics in metabolomics--a review in human disease diagnosis

scientific article

Chemometrics in metabonomics.

scientific article

Complete Genome Sequence of Francisella guangzhouensis Strain 08HL01032T, Isolated from Air-Conditioning Systems in China

scientific article

Cytokine Profiles in Autoantibody Defined Subgroups of Systemic Lupus Erythematosus

scientific article published on 18 February 2019

Data integration in plant biology: the O2PLS method for combined modeling of transcript and metabolite data

scientific article

Data mining and visualisation: general discussion

scientific article published on 01 August 2019

Design of experiments on 135 cloned poplar trees to map environmental influence in greenhouse

scientific article published on November 19, 2010

Diagnostic properties of metabolic perturbations in rheumatoid arthritis

scientific article published on 8 February 2011

Dynamic ultrasound imaging—A multivariate approach for the analysis and comparison of time-dependent musculoskeletal movements

scientific article published on September 27, 2012

EGFR gene variants are associated with specific somatic aberrations in glioma

scientific article

Environmental and hormonal regulation of the activity-dormancy cycle in the cambial meristem involves stage-specific modulation of transcriptional and metabolic networks

scientific article

Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: From extraction to data analysis

scientific article

Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies.

scientific article published in January 2005

Extraction and GC/MS analysis of the human blood plasma metabolome

scientific article

Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets

scientific article

From Data Processing to Multivariate Validation - Essential Steps in Extracting Interpretable Information from Metabolomics Data

scientific article published on July 1, 2011

Generalized Subset Designs in Analytical Chemistry.

scientific article published on 12 May 2017

Global expression profiling in leaves of free-growing aspen

scientific article

Global, local and unique decompositions in OnPLS for multiblock data analysis

scientific article

Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance

scientific article published on 11 April 2016

High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses

scientific article

Integrated analysis of transcript, protein and metabolite data to study lignin biosynthesis in hybrid aspen

scientific article

Joint and Unique Multiblock Analysis for Integration and Calibration Transfer of NIR Instruments

scientific article published on 21 February 2019

Joint and unique multiblock analysis of biological data - multiomics malaria study

scientific article published on 01 August 2019

K-OPLS package: kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space

scientific article

Kernel-based orthogonal projections to latent structures (K-OPLS)

scholarly article by Mattias Rantalainen et al published 2007 in Journal of Chemometrics

LAMINA: a tool for rapid quantification of leaf size and shape parameters

scientific article (publication date: 22 July 2008)

LIVECell-A large-scale dataset for label-free live cell segmentation

scientific article published on 30 August 2021

MASQOT-GUI: spot quality assessment for the two-channel microarray platform

scientific article

MASQOT: a method for cDNA microarray spot quality control

scientific article

Metabolic Profiling of Multiorgan Samples: Evaluation of MODY5/RCAD Mutant Mice

scientific article published on 15 June 2018

Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjögren's Syndrome and Systemic Sclerosis

scientific article

Metabolic profiling of zebrafish embryo development from blastula period to early larval stages.

scientific article published on 14 May 2019

Metabolic responses to change in disease activity during tumor necrosis factor inhibition in patients with rheumatoid arthritis

scientific article published on 24 May 2012

Metabolite Signature during Short-Day Induced Growth Cessation in Populus

scientific article

Metabolite and Lipid Profiling of Biobank Plasma Samples Collected Prior to Onset of Rheumatoid Arthritis

scientific article

Metabolomics study of fatigue in patients with rheumatoid arthritis naïve to biological treatment

scientific article

Modelling human musculoskeletal functional movements using ultrasound imaging

scientific article

Multi-Organ Contribution to the Metabolic Plasma Profile Using Hierarchical Modelling

scientific article published on 18 June 2015

O2-PLS, a two-block (X-Y) latent variable regression (LVR) method with an integral OSC filter

scientific article published in 2003

OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification

article

OPLS in batch monitoring - Opens up new opportunities

scientific article published on 5 December 2014

OnPLS integration of transcriptomic, proteomic and metabolomic data shows multi-level oxidative stress responses in the cambium of transgenic hipI- superoxide dismutase Populus plants

scientific article (publication date: 17 December 2013)

OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma

scientific article published on 02 November 2018

Orthogonal PLS (OPLS) Modeling for Improved Analysis and Interpretation in Drug Design

scientific article published on 16 April 2012

Orthogonal projections to latent structures (O-PLS)

scholarly article by Johan Trygg & Svante Wold published 2002 in Journal of Chemometrics

Orthogonal projections to latent structures as a strategy for microarray data normalization

scientific article

Orthogonal projections to latent structures discriminant analysis modeling on in situ FT-IR spectral imaging of liver tissue for identifying sources of variability

scientific article

Overexpression of vesicle-associated membrane protein PttVAP27-17 as a tool to improve biomass production and the overall saccharification yields in Populus trees

scientific article

Piecewise multivariate modelling of sequential metabolic profiling data

scientific article

Predictive metabolite profiling applying hierarchical multivariate curve resolution to GC-MS data--a potential tool for multi-parametric diagnosis

scientific article

Proposed minimum reporting standards for data analysis in metabolomics

article

Protein expression in tension wood formation monitored at high tissue resolution in Populus.

scientific article published on 13 June 2017

Quantification of run order effect on chromatography - mass spectrometry profiling data

scientific article published on 05 July 2018

Quantitative proteomics reveals protein profiles underlying major transitions in aspen wood development

scientific article

Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets

scientific article

Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice

scientific article published on October 2006

Strategy for Minimizing Between-Study Variation of Large-Scale Phenotypic Experiments Using Multivariate Analysis

scientific article published on October 16, 2012

Strategy for optimizing LC-MS data processing in metabolomics: a design of experiments approach.

scientific article

The effects of thawing on the plasma metabolome: evaluating differences between thawed plasma and multi-organ samples.

scientific article published on 17 April 2017

Unlocking interpretation in near infrared multivariate calibrations by orthogonal partial least squares

scientific article

Using chemometrics for navigating in the large data sets of genomics, proteomics, and metabonomics (gpm).

scientific article

Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models

scientific article

Visualization of descriptive multiblock analysis

scientific article published in 2018

doepipeline: a systematic approach to optimizing multi-level and multi-step data processing workflows

scientific article published on 15 October 2019