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List of works by Xi Chen

A Fungal P450 Enzyme from Thanatephorus cucumeris with Steroid Hydroxylation Capabilities

scientific article published on 18 June 2018

A novel meso-Diaminopimelate dehydrogenase from Symbiobacterium thermophilum: overexpression, characterization, and potential for D-amino acid synthesis

scientific article

A sialic acid aldolase from Peptoclostridium difficile NAP08 with 4-hydroxy-2-oxo-pentanoate aldolase activity.

scientific article published on 10 July 2016

Characterization of (R)-selective amine transaminases identified by in silico motif sequence blast

scientific article published on 01 October 2014

Cloning and characterization of a novel carbonyl reductase for asymmetric reduction of bulky diaryl ketones

scientific article published in January 2013

Distinct Regioselectivity of Fungal P450 Enzymes for Steroidal Hydroxylation

scientific article published on 29 August 2019

Efficient reductive desymmetrization of bulky 1,3-cyclodiketones enabled by structure-guided directed evolution of a carbonyl reductase ⬇️

scholarly article

Engineering of l-threonine aldolase for the preparation of 4-(methylsulfonyl)phenylserine, an important intermediate for the synthesis of florfenicol and thiamphenicol

scientific article published on 09 March 2020

Engineering the meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum by site saturation mutagenesis for D-phenylalanine synthesis

scientific article published on 31 May 2013

Flavin Oxidoreductase‐Mediated Regeneration of Nicotinamide Adenine Dinucleotide with Dioxygen and Catalytic Amount of Flavin Mononucleotide for One‐Pot Multi‐Enzymatic Preparation of Ursodeoxycholic Acid

scholarly article

Highly Atom Economic Synthesis of d-2-Aminobutyric Acid through an In Vitro Tri-enzymatic Catalytic System

scientific article

Highly Diastereoselective Synthesis of 2,2-Disubstituted Cyclopentane-1,3-diols via Stepwise Ketone Reduction Enabling Concise Chirality Construction

scientific article published on 15 July 2020

Highly Efficient Synthesis of Optically Pure (S)-1-phenyl-1,2-ethanediol by a Self-Sufficient Whole Cell Biocatalyst

scientific article

Molecular Characterization of a Novel N-Acetylneuraminate Lyase from a Deep-Sea Symbiotic Mycoplasma.

scientific article published on 5 March 2018

New product identification in the sterol metabolism by an industrial strain Mycobacterium neoaurum NRRL B-3805.

scientific article published on 7 February 2018

Regio- and stereoselective reduction of 17-oxosteroids to 17β-hydroxysteroids by a yeast strain Zygowilliopsis sp. WY7905.

scientific article published on 15 November 2016

Structural analysis reveals the substrate-binding mechanism for the expanded substrate specificity of mutant meso-diaminopimelate dehydrogenase.

scientific article published on 6 March 2015

Structural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum

scientific article

Structure-Guided Directed Evolution of a Carbonyl Reductase Enables the Stereoselective Synthesis of (2S,3S)-2,2-Disubstituted-3-hydroxycyclopentanones via Desymmetric Reduction

scientific article published on 22 April 2020

[Biochemical characterization and substrate profile of a highly enantioselective carbonyl reductase from Pichia pastoris].

scientific article published in February 2013

[Effect of residue Y76 on co-enzyme specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum]

scientific article published in July 2015

[High throughput screening of active and stereoselective carbonyl reductases].

scientific article

[Molecular cloning and characterization of a N-acetylneuraminate lyase gene from Staphylococcus hominis].

scientific article published in April 2013

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