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List of works by Chunquan Sheng

Chalcone: A Privileged Structure in Medicinal Chemistry

scientific article published on 10 May 2017

Discovery of Carboline Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcal Meningitis

scientific article published on 22 February 2019

Discovery of Janus Kinase 2 (JAK2) and Histone Deacetylase (HDAC) Dual Inhibitors as a Novel Strategy for the Combinational Treatment of Leukemia and Invasive Fungal Infections

scientific article published on 14 July 2018

Discovery of Novel KRAS-PDEδ Inhibitors by Fragment-Based Drug Design.

scientific article published on 6 March 2018

Discovery of Simplified Sampangine Derivatives with Potent Antifungal Activities against Cryptococcal Meningitis

scientific article published on 22 May 2019

Drug Repurposing of Haloperidol: Discovery of New Benzocyclane Derivatives as Potent Antifungal Agents against Cryptococcosis and Candidiasis

scientific article published on 08 October 2019

Emerging New Targets for the Treatment of Resistant Fungal Infections.

scientific article published on 2 January 2018

Identification of potent catalytic inhibitors of human DNA topoisomerase II by structure-based virtual screening

scientific article published on 24 May 2018

Identification of pyrazolopyridine derivatives as novel spleen tyrosine kinase inhibitors

scientific article published on 27 June 2018

Improving the Potency of Cancer Immunotherapy by Dual Targeting of IDO1 and DNA.

scientific article

Novel Carboline Fungal Histone Deacetylase (HDAC) Inhibitors for Combinational Treatment of Azole-Resistant Candidiasis

scientific article published on 27 December 2020

Novel non-peptidic small molecule inhibitors of secreted aspartic protease 2 (SAP2) for the treatment of resistant fungal infections

scientific article published on 15 November 2018

One-Pot Synthesis of Deuterated Aldehydes from Arylmethyl Halides

scientific article published on 08 March 2018

Organocatalytic Asymmetric Synthesis of Spiro-Tetrahydrothiophene Oxindoles Bearing Four Contiguous Stereocenters by One-Pot Michael-Henry-Cascade-Rearrangement Reactions.

scientific article

Scaffold Hopping of Natural Product Evodiamine: Discovery of a Novel Antitumor Scaffold with Excellent Potency against Colon Cancer

scientific article published on 10 January 2020

Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors.

scientific article published on 8 September 2017

Small Molecules Simultaneously Inhibiting p53-Murine Double Minute 2 (MDM2) Interaction and Histone Deacetylases (HDACs): Discovery of Novel Multitargeting Antitumor Agents

scientific article published on 09 August 2018

Structural Biology-Inspired Discovery of Novel KRAS-PDEδ Inhibitors

scientific article published on 20 September 2017

Structural Simplification of Natural Products

scientific article published on 07 February 2019

Tackling Fungal Resistance by Biofilm Inhibitors.

scientific article