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List of works by Adrienne M Flanagan

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma

scientific article

A diagnostic approach to bone tumours

scientific article published on 27 October 2017

Abstract 4593: Genome-wide association study identifies novel loci associated with osteosarcoma

Activating mutations in the MAP-kinase pathway define non-ossifying fibroma of bone

scientific article published on 24 January 2019

An assessment of the ability of human bone marrow cultures to generate osteoclasts ⬇️

scientific article published on June 1, 1992

An update of molecular pathology of bone tumors. Lessons learned from investigating samples by next generation sequencing

scientific article published on 24 December 2018

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Androstenedione treatment reduces loss of cancellous bone volume in ovariectomised rats in a dose-responsive manner and the effect is not mediated by oestrogen ⬇️

scientific article published on February 1, 1998

Aromatase cytochrome P450 transcripts are detected in fractured human bone but not in normal skeletal tissue ⬇️

scientific article published on November 1, 1997

Assessment of MUC4 expression in primary bone tumours ⬇️

scientific article published on May 13, 2013

Assessment of integrase interactor 1 (INI‐1) expression in primary tumours of bone ⬇️

scientific article published on 07 September 2012

Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification.

scientific article published on 18 January 2017

Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements

scientific article published on 04 March 2019

Clinical outcome in patients with peripherally-sited atypical lipomatous tumours and dedifferentiated liposarcoma.

scientific article published on 16 March 2015

Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing.

scientific article published on 2 April 2018

Dedifferentiated Chondrosarcoma Demonstrating Osteosarcomatous Differentiation

scientific article published on 15 June 2018

Detection of USP6 gene rearrangement in nodular fasciitis: an important diagnostic tool ⬇️

scientific article published on June 9, 2013

Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast-rich mimics.

scientific article published on 16 March 2015

Digital PCR analysis of circulating tumor DNA: a biomarker for chondrosarcoma diagnosis, prognostication, and residual disease detection.

scientific article

Drivers underpinning the malignant transformation of giant cell tumour of bone

scientific article published on 31 August 2020

Estrogen synthesis by osteoblast cell lines

scientific article published on October 1, 1992

FOS Expression in Osteoid Osteoma and Osteoblastoma: A Valuable Ancillary Diagnostic Tool

scientific article published on 01 December 2019

Fibroblastic growth factor receptor 1 amplification in osteosarcoma is associated with poor response to neo-adjuvant chemotherapy.

scientific article

Frequency of Mouse Double Minute 2 (MDM2) and Mouse Double Minute 4 (MDM4) amplification in parosteal and conventional osteosarcoma subtypes ⬇️

scientific article published on November 10, 2011

GNAS mutations are not detected in parosteal and low-grade central osteosarcomas

scientific article

Generating Human Osteoclasts In Vitro from Bone Marrow and Peripheral Blood

scientific article published on 01 January 2003

Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients

scientific article published on 6 December 2017

Genome-wide association study identifies two susceptibility loci for osteosarcoma

scientific article (publication date: July 2013)

H3K27me3 expression and methylation status in histological variants of malignant peripheral nerve sheath tumours

scientific article published on 15 July 2020

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Inhibition of bone resorption by 17β-estradiol in human bone marrow cultures ⬇️

scientific article published on 01 April 1998

Inhibition of bone resorption by bisphosphonates: Interactions between bisphosphonates, osteoclasts, and bone ⬇️

scientific article published on December 1, 1991

Inhibition of gamma-secretases alters both proliferation and differentiation of mesenchymal stem cells

scientific article published in April 2007

Injury signals cooperate with Nf1 loss to relieve the tumor-suppressive environment of adult peripheral nerve

scientific article published on 26 September 2013

Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance

scientific article published on 14 July 2015

Is conservative treatment for adenocarcinoma in situ of the cervix safe? ⬇️

scientific article published on November 1, 2001

Isocitrate dehydrogenase 1 mutations (IDH1) and p16/CDKN2A copy number change in conventional chondrosarcomas

scientific article

Locally aggressive fibrous dysplasia ⬇️

scientific article published on June 13, 2013

MRI characteristics of lipoma and atypical lipomatous tumor/well-differentiated liposarcoma: retrospective comparison with histology and MDM2 gene amplification ⬇️

scientific article published on September 18, 2012

Macrophage Colony-Stimulating Factor Increases Bone Resorption by Osteoclasts Disaggregated From Human Fetal Long Bones ⬇️

scientific article published on April 1, 1998

MicroRNA profiling of peripheral nerve sheath tumours identifies miR-29c as a tumour suppressor gene involved in tumour progression ⬇️

scientific article published on November 22, 2012

Next-generation sequencing is highly sensitive for the detection of beta-catenin mutations in desmoid-type fibromatoses

scientific article published on 3 April 2015

Ovarian cellular fibroma harbouring an isocitrate dehydrogenase 1 (1DH1) mutation in a patient with Ollier disease: evidence for a causal relationship ⬇️

scientific article published on January 24, 2013

P63 does not regulate brachyury expression in human chordomas and osteosarcomas ⬇️

scientific article published on October 18, 2011

PRDM10-rearranged Soft Tissue Tumor: A Clinicopathologic Study of 9 Cases

scientific article published on 01 April 2019

Physiological plasma levels of androgens reduce bone loss in the ovariectomized rat ⬇️

scientific article published on 01 February 1998

Post-translational regulation contributes to the loss of LKB1 expression through SIRT1 deacetylase in osteosarcomas.

scientific article published on 20 June 2017

Prostaglandin E2, Interleukin 1α, and Tumor Necrosis Factor-α Increase Human Osteoclast Formation and Bone Resorption in Vitro* ⬇️

scientific article published on July 1, 1998

Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma: characterization of five cases ⬇️

scientific article published on 05 February 2013

Quantitatively characterizing benthic community-habitat relationships in soft-sediment, nearshore environments to yield useful results for management

scientific article published on 31 August 2019

Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors

scientific article published in Science

Recurrent rearrangements of FOS and FOSB define osteoblastoma.

scientific article

SUMO ligase activity of vertebrate Mms21/Nse2 is required for efficient DNA repair but not for Smc5/6 complex stability ⬇️

scientific article published on August 24, 2012

Sarcoma classification by DNA methylation profiling

scientific article published on 21 January 2021

Sensitivity of MDM2 amplification and unexpected multiple faint alphoid 12 (alpha 12 satellite sequences) signals in atypical lipomatous tumor ⬇️

scientific article published on June 15, 2012

Soft tissue angiofibroma: Clinicopathologic, immunohistochemical and molecular analysis of 14 cases

scientific article published on 22 June 2017

Stimulation of bone nodule formation in vitro by prostaglandins E1 and E2 ⬇️

scientific article published on 01 January 1992

Suppression of deacetylase SIRT1 mediates tumor-suppressive NOTCH response and offers a novel treatment option in metastatic Ewing sarcoma

scientific article published on 3 October 2014

Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort

scientific article published on 25 January 2019

Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement

scientific article published on 04 July 2019

Systematic Review of Clinical, Radiologic, and Histologic Features of Benign Notochordal Cell Tumors: Implications for Patient Management

scientific article published on 14 June 2019

The H3F3 K36M mutant antibody is a sensitive and specific marker for the diagnosis of chondroblastoma

scientific article published on 4 February 2016

The relationship between observational scale and explained variance in benthic communities

scientific article

Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways

scientific article published on 01 March 2019

Undifferentiated pleomorphic sarcomas with PRDM10 fusions have a distinct gene expression profile

scientific article published on 27 August 2019

Update on the biologic effects of macrophage colony-stimulating factor ⬇️

scientific article published on May 1, 1998

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