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List of works by James E Rothman

A Programmable DNA Origami Platform to Organize SNAREs for Membrane Fusion

scientific article published on 03 March 2016

A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion

scientific article (publication date: 24 July 2011)

A half-zippered SNARE complex represents a functional intermediate in membrane fusion.

scientific article published on 18 February 2014

Accelerating SNARE-Mediated Membrane Fusion by DNA-Lipid Tethers

scientific article published on 06 October 2015

COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function

scientific article

Calcium sensitive ring-like oligomers formed by synaptotagmin

scientific article

Circular oligomerization is an intrinsic property of synaptotagmin.

scientific article published on 29 August 2017

Common intermediates and kinetics, but different energetics, in the assembly of SNARE proteins

scientific article

Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state

scientific article published on 24 July 2011

Complexin cross-links prefusion SNAREs into a zigzag array

scientific article

Energetics and dynamics of SNAREpin folding across lipid bilayers

scientific article published on 30 September 2007

FRAP to Characterize Molecular Diffusion and Interaction in Various Membrane Environments.

scientific article

Formation of Giant Unilamellar Proteo-Liposomes by Osmotic Shock

scientific article published on 15 June 2015

High throughput monitoring of single vesicle fusion using free-standing membranes and automated analysis

scientific article

Highly Reproducible Physiological Asymmetric Membrane with Freely Diffusing Embedded Proteins in a 3D-Printed Microfluidic Setup

scientific article published on 12 April 2019

Hypothesis - buttressed rings assemble, clamp, and release SNAREpins for synaptic transmission.

scientific article published on 6 October 2017

Kinetic barriers to SNAREpin assembly in the regulation of membrane docking/priming and fusion.

scientific article published on 06 September 2016

Low energy cost for optimal speed and control of membrane fusion

scientific article published on 23 January 2017

Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses

scientific article published on 7 November 2017

Preparation and characterization of SNARE-containing nanodiscs and direct study of cargo release through fusion pores.

scientific article published on 18 April 2013

Re-visiting the trans insertion model for complexin clamping

scientific article

Rearrangements under confinement lead to increased binding energy of Synaptotagmin-1 with anionic membranes in Mg2+ and Ca2

scientific article published on 10 April 2018

Ring-like oligomers of Synaptotagmins and related C2 domain proteins

scientific article

S-Palmitoylation Sorts Membrane Cargo for Anterograde Transport in the Golgi

scientific article published on 01 November 2018

Stability, folding dynamics, and long-range conformational transition of the synaptic t-SNARE complex

scientific article

Synaptotagmin oligomers are necessary and can be sufficient to form a Ca2+ -sensitive fusion clamp

scientific article published on 18 January 2019

Synergistic roles of Synaptotagmin-1 and complexin in calcium-regulated neuronal exocytosis

scientific article published on 13 May 2020

TANGO1 membrane helices create a lipid diffusion barrier at curved membranes

scientific article published on 26 May 2020

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