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List of works by Shereen Ezzat

1alpha,25-Dihydroxyvitamin D3 targets PTEN-dependent fibronectin expression to restore thyroid cancer cell adhesiveness

scientific article published on 12 May 2005

A Growth Hormone Receptor Mutation Impairs Growth Hormone Autofeedback Signaling in Pituitary Tumors

scientific article published on 01 August 2007

A Minimally Invasive Approach to the Management of Bronchial Carcinoid Tumors Associated with Ectopic Cushing's Syndrome

scientific article published on 01 January 1998

A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin.

scientific article published on 17 September 2007

A detailed spatial analysis on contrasting cancer incidence patterns in thyroid and lung cancer in Toronto women

scientific article

A high-throughput proteomic approach provides distinct signatures for thyroid cancer behavior.

scientific article

A large and aggressive fibromatosis in the axilla: a rare case report and review of the literature.

scientific article

A randomized, controlled, multicentre trial comparing pegvisomant alone with combination therapy of pegvisomant and long-acting octreotide in patients with acromegaly

scientific article published on 2 May 2009

A systematic review examining the effects of therapeutic radioactive iodine on ovarian function and future pregnancy in female thyroid cancer survivors

scientific article published on 13 February 2008

A systematic review of randomized controlled trials for management of persistent post-treatment fatigue in thyroid cancer survivors

scientific article

A systematic review of the gonadal effects of therapeutic radioactive iodine in male thyroid cancer survivors

scientific article published on 31 October 2007

AACE Medical Guidelines for Clinical Practice for the diagnosis and treatment of acromegaly

scientific article published in May 2004

AACE/ACE Disease State Clinical Review: Dopamine Agonists for Hyperprolactinemia and the Risk of Cardiac Valve Disease

scientific article published on June 2014

AIP Mutations are not Identified in Patients with Sporadic Pituitary Adenomas

scientific article published on 01 January 2007

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: CLINICAL RELEVANCE OF MACROPROLACTIN IN THE ABSENCE OR PRESENCE OF TRUE HYPERPROLACTINEMIA.

scientific article published in December 2015

Acromegaly: re-thinking the cancer risk

scientific article

Adjuvant Growth Hormone for Ovulation Induction with Gonadotropins in the Treatment of a Woman with Hypopituitarism ⬇️

scientific article published on July 31, 2012

Aggressive Pituitary Tumors or Localized Pituitary Carcinomas: Defining Pituitary Tumors

An essential role for the hematopoietic transcription factor Ikaros in hypothalamic-pituitary-mediated somatic growth

scientific article

Anabolic growth hormone action improves submaximal measures of physical performance in patients with HIV-associated wasting

scientific article published on 10 May 2005

Basic fibroblast growth factor expression by two prolactin and thyrotropin-producing pituitary adenomas

article

Basis for Physician Recommendations for Adjuvant Radioiodine Therapy in Early-Stage Thyroid Carcinoma: Principal Findings of the Canadian-American Thyroid Cancer Survey

article

Biomarkers of aggressive pituitary adenomas

scientific article published on 30 August 2012

Canadian consensus guidelines for the diagnosis and management of acromegaly

scientific article published on 01 February 2006

Canadian guidelines for the management of adult growth hormone deficiency

scientific article

Cancer-related worry in Canadian thyroid cancer survivors

scientific article

Carney complex with adrenal cortical carcinoma

scientific article

Case report: Adrenal LH/hCG receptor overexpression and gene amplification causing pregnancy-induced Cushing's syndrome

scientific article published in January 2009

Chromatin remodeling and histone modifications in pituitary tumors

scientific article published on 07 January 2010

Circulating and synovial levels of IGF-I, cytokines, physical function and anthropometry differ in women awaiting total knee arthroplasty when compared to men

scientific article published on 01 March 2005

Clinical Implications of Accurate Subtyping of Pituitary Adenomas: Perspectives from the Treating Physician

scientific article

Clinical predictors of advanced sellar masses

scientific article published on 01 October 2007

Clonality of thyroid nodules in sporadic goiter

scientific article published on June 1995

Comparison of body composition assessment methods in patients with human immunodeficiency virus-associated wasting receiving growth hormone

scientific article published on 6 June 2006

Complete anterior pituitary failure and postpartum cardiomyopathy

scientific article published in May 2006

Complex endocrinopathies in MEN-1: diagnostic dilemmas in endocrine oncology

scientific article

Concerns of low-risk thyroid cancer survivors

Controversies in Papillary Microcarcinoma of the Thyroid

scholarly article by Monique Piersanti et al published 2003 in Endocrine Pathology

Controversies in papillary microcarcinoma of the thyroid

scientific article published on January 2003

CtBP1 interacts with Ikaros and modulates pituitary tumor cell survival and response to hypoxia

scientific article

Current management of papillary thyroid microcarcinoma in Canada

scientific article published on 14 August 2014

Current views on pathogenesis of pituitary tumors

Cushing's Syndrome from an Ectopic Pituitary Adenoma with Peliosis: A Histological, Immunohistochemical, and Ultrastructural Study and Review of the Literature

scientific article

Cyclin D1 protein expression predicts metastatic behavior in thyroid papillary microcarcinomas but is not associated with gene amplification

article

Cytoplasmic expression of fibroblast growth factor receptor-4 in human pituitary adenomas: relation to tumor type, size, proliferation, and invasiveness

scientific article published on April 2004

Decision aid on radioactive iodine treatment for early stage papillary thyroid cancer--a randomized controlled trial

scientific article

Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells

scientific article published on 10 June 2008

Dexamethasone increases ubiquitin transcription through an SP-1 dependent mechanism in multiple myeloma cells

scientific article published on 04 January 2008

Diagnosis and management of gastrointestinal neuroendocrine tumors: An evidence-based Canadian consensus

scientific article

Diagnosis and management of hyperprolactinemia

scientific article

Dietary iodine restriction in preparation for radioactive iodine treatment or scanning in well-differentiated thyroid cancer: a systematic review.

scientific article published on October 2010

Distinct transcriptional control and action of fibroblast growth factor receptor 4 in differentiating skeletal muscle cells

scientific article

Dopaminergic resistant prolactinomas in the peripubertal population

scientific article published on 01 July 2006

Dual inhibition of RET and FGFR4 restrains medullary thyroid cancer cell growth.

scientific article published on February 2005

Emerging trends in the diagnosis and treatment of acromegaly in Canada ⬇️

scientific article published on April 27, 2013

Endocrine Organs

Endocrine Organs

Enhanced B-Raf protein expression is independent of V600E mutant status in thyroid carcinomas

scientific article published on 21 August 2007

Epigenetic control in pituitary tumors

scientific article published on 15 July 2008

Epigenetic dysregulation in thyroid neoplasia

scientific article published on June 2008

Epigenetic silencing through DNA and histone methylation of fibroblast growth factor receptor 2 in neoplastic pituitary cells

scientific article published on May 2007

Epigenetically controlled fibroblast growth factor receptor 2 signaling imposes on the RAS/BRAF/mitogen-activated protein kinase pathway to modulate thyroid cancer progression

scientific article published on June 2007

Epigenetics of pituitary tumors: Pathogenetic and therapeutic implications

scientific article

Erratum to: Case Report: Adrenal LH/hCG Receptor Overexpression and Gene Amplification Causing Pregnancy-Induced Cushing’s Syndrome

article

Establishment and Characterization of a Human Neuroendocrine Tumor Xenograft

scientific article published on 11 April 2016

Evaluation of the WHO 2010 grading and AJCC/UICC staging systems in prognostic behavior of intestinal neuroendocrine tumors

scientific article

Exercise training benefits growth hormone (GH)-deficient adults in the absence or presence of GH treatment

scientific article published in December 2003

Exploring the Life Impact of Treated Low-Risk Thyroid Cancer

scientific article published in April 2016

Exploring the relationship between patients' information preference style and knowledge acquisition process in a computerized patient decision aid randomized controlled trial.

scientific article published on 19 June 2015

Expression of Ki-67, PTTG1, FGFR4, and SSTR 2, 3, and 5 in nonfunctioning pituitary adenomas: a high throughput TMA, immunohistochemical study.

scientific article

Expression of the melanoma-associated antigen is associated with progression of human thyroid cancer

scientific article published on 4 March 2009

FGFR2 isoforms support epithelial-stromal interactions in thyroid cancer progression

scientific article

FGFR4 polymorphic alleles modulate mitochondrial respiration: A novel target for somatostatin analog action in pituitary tumors

scientific article published on 09 December 2016

FGFR4 polymorphic variants modulate phenotypic features of Cushing disease

scientific article published on 13 March 2014

Familial pheochromocytoma and renal cell carcinoma syndrome: TMEM127 as a novel candidate gene for the association

article

Fibroblast growth factor receptor 4 (FGFR4) mediates signaling to the prolactin but not the FGFR4 promoter

scientific article published on September 2002

Fibroblast growth factor receptor 4 is a target for the zinc-finger transcription factor Ikaros in the pituitary

scientific article

Fibroblast growth factor receptors as molecular targets in thyroid carcinoma.

scientific article

Fractional thermoelasticity applications for porous asphaltic materials

scholarly article by Magdy Ezzat & Shereen Ezzat published 12 April 2016 in Petroleum Science

Functional cardiac paraganglioma associated with a rare SDHC mutation

scientific article published on September 2014

GNAq mutations are not identified in papillary thyroid carcinomas and hyperfunctioning thyroid nodules.

scientific article

Genetic Events in the Evolution of Thyroid Cancer

article

Genetic and epigenetic mechanisms down-regulate FGF receptor 2 to induce melanoma-associated antigen A in breast cancer

scientific article

Genetics and Epigenetics of Endocrine Neoplasia

article

Genetics and proteomics of pituitary tumors

scientific article

Genomic approaches to problems in pituitary neoplasia

scientific article published on September 2014

Growth factors and their receptors in the genesis and treatment of thyroid cancer.

scientific article

Growth hormone treatment improves peripheral muscle oxygen extraction-utilization during exercise in patients with human immunodeficiency virus-associated wasting: a randomized controlled trial

scientific article published in October 2004

Growth patterns of pituitary adenomas and histopathological correlates.

scientific article

High-throughput drug library screening identifies colchicine as a thyroid cancer inhibitor

scientific article

Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer

scientific article published on 04 June 2009

Hormone profiling, WHO 2010 grading, and AJCC/UICC staging in pancreatic neuroendocrine tumor behavior

scientific article published on 06 August 2013

Hypothalamic Disease ☆

IGF-I and testosterone levels as predictors of bone mineral density in healthy, community-dwelling men.

scientific article published in April 2004

Ikaros and its interacting partner CtBP target the metalloprotease ADAMTS10 to modulate pituitary cell function

scientific article published in November 2016

Ikaros integrates endocrine and immune system development

scientific article

Ikaros integrates endocrine and immune system development

article

Ikaros is regulated through multiple histone modifications and deoxyribonucleic acid methylation in the pituitary

scientific article published on 6 March 2007

Ikaros isoforms in human pituitary tumors: distinct localization, histone acetylation, and activation of the 5' fibroblast growth factor receptor-4 promoter

scientific article published on September 2003

Ikaros modulates cholesterol uptake: a link between tumor suppression and differentiation

scientific article published in May 2008

Immunohistochemical Diagnosis of Papillary Thyroid Carcinoma

Inhibin-expressing clear cell neuroendocrine tumor of the ampulla: an unusual presentation of von Hippel-Lindau disease.

scientific article published on 4 August 2013

Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation

scientific article

Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function

scientific article

Intrathyroidal Parathyroid Carcinoma: An Atypical Thyroid Lesion

Is Granulomatous Thyroiditis a Complication of Breast Implants?

scientific article published on 01 January 2002

Is autoimmune pituitary disease underdiagnosed?

scientific article published on 24 July 2007

Lessons learned from thyroglobulin concentrations after total thyroidectomy and radioactive iodine ablation for differentiated thyroid cancer

scientific article published on 08 July 2015

Loss of heterozygosity and DNA methylation affect germline fibroblast growth factor receptor 4 polymorphism to direct allelic selection in breast cancer

scientific article

Male occult triple-negative breast cancer with dermatomyositis: a case report and review of the literature

scientific article published on 14 November 2017

Malignant pheochromocytoma secreting vasoactive intestinal peptide and response to sunitinib: a case report and literature review

scientific article

Management of Lesions of the Pituitary Stalk and Hypothalamus

Mechanisms of disease: The pathogenesis of pituitary tumors

scientific article published on April 2006

Mechanisms of pituitary tumorigenesis

Medical management of pituitary adenomas: structural and ultrastructural changes

scientific article

Metabolic glucose status and pituitary pathology portend therapeutic outcomes in acromegaly

scientific article

Metastatic Thyroid Carcinoma to the Gastric Body

article

Mice lacking the transcription factor Ikaros display behavioral alterations of an anti-depressive phenotype

scientific article published on 5 February 2008

Microadenomatosis of the Pancreas in von Hippel-Lindau Disease

scientific article published on 01 December 2006

Molecular basis of pituitary development and cytogenesis

scientific article published in January 2004

Myostatin is a skeletal muscle target of growth hormone anabolic action

scientific article published in November 2003

NG2 targets tumorigenic Rb inactivation in Pit1-lineage pituitary cells

scientific article published on 5 April 2016

Oncogene profile of papillary thyroid carcinoma

Osteopontin (OPN) expression in thyroid carcinoma

scientific article

Osteopontin stimulates invasion of NCI-h295 cells but is not associated with survival in adrenocortical carcinoma

scientific article published on June 2009

Overexpression of Cyclin D1 and Underexpression of p27 Predict Lymph Node Metastases in Papillary Thyroid Carcinoma

scientific article published on 01 April 2002

Overt Immune Dysfunction after Cushing's Syndrome Remission: A Consecutive Case Series and Review of the Literature ⬇️

scientific article published on August 3, 2011

PANCREATIC INCIDENTALOMAS: IS IT NET OR NOT?

scientific article published on 26 February 2016

PM-13IDENTIFICATION OF THERAPEUTIC TARGETS IN AN INTRACRANIAL XENOGRAFT MODEL OF PITUITARY ADENOMA.

scientific article

Pancreatic Endocrine Pathology in von Hippel–Lindau Disease: An Expanding Spectrum of Lesions

scientific article published on 01 January 2004

Pancreatic Neuroendocrine Tumors Producing GHRH, GH, Ghrelin, PTH, or PTHrP

article

Pathogenetic mechanisms in thyroid follicular-cell neoplasia

scientific article

Pathology, pathophysiology, and treatment strategies of endocrine disorders and their cardiac complications

scientific article published on August 2013

Patients' experiences following local-regional recurrence of thyroid cancer: a qualitative study.

scientific article

Persistent posttreatment fatigue in thyroid cancer survivors: a scoping review

scientific article published on June 2014

Pharmacological approach to the treatment of acromegaly

scientific article published on 15 April 2004

Pharmacological options in the treatment of acromegaly.

scientific article

Pituitary Adenomas Presenting as Sinonasal or Nasopharyngeal Masses: A Case Series Illustrating Potential Diagnostic Pitfalls

scientific article published on 22 December 2016

Pituitary Tumor Pathogenesis—The Hunt for Novel Candidate Genes Continues ⬇️

scientific article published on 01 November 2003

Pituitary acromegaly: not one disease

scientific article published on 25 January 2017

Pituitary tumor AP-2alpha recognizes a cryptic promoter in intron 4 of fibroblast growth factor receptor 4.

scientific article

Pituitary tumor-derived fibroblast growth factor receptor 4 isoform disrupts neural cell-adhesion molecule/N-cadherin signaling to diminish cell adhesiveness: a mechanism underlying pituitary neoplasia

scientific article published on July 2004

Pregnancy in acromegaly: experience from two referral centers and systematic review of the literature ⬇️

scientific article published on February 1, 2012

Primary mediastinal paraganglioma associated with a familial variant in the succinate dehydrogenase B subunit gene

scientific article

Progression of subacute (de Quervain's) thyroiditis into Hashimoto's thyroiditis

scientific article published on 01 June 2004

Protocol for the Examination of Specimens From Patients With Primary Pituitary Tumors ⬇️

scientific article published on 01 May 2011

Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas ⬇️

scientific article published on February 2014

Pseudopheochromocytoma of Pregnancy ⬇️

scientific article published on September 1, 2003

Rationale and evidence for sunitinib in the treatment of malignant paraganglioma/pheochromocytoma

scientific article

Re: Quality of life and symptom impact of thyroid cancer: A cross-sectional survey of Canadian patients

article

Regional Differences in Opinions on Adjuvant Radioactive Iodine Treatment of Thyroid Carcinoma within Canada and the United States

article

Retraction. Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

scientific article published on 3 August 2015

SUN-453 Absence of Crooke's Hyaline Changes May Predict Worse Outcomes in Patients with Cushing Disease.

scientific article published on 30 April 2019

Second primary malignancy risk after radioactive iodine treatment for thyroid cancer: a systematic review and meta-analysis

scientific article published on May 2009

Second primary malignancy risk in thyroid cancer survivors: a systematic review and meta-analysis

scientific article published on December 2007

Short-term safety and efficacy of human GH replacement therapy in 595 adults with GH deficiency: a comparison of two dosage algorithms

scientific article published in May 2002

Silent subtype 3 pituitary adenomas are not always silent and represent poorly differentiated monomorphous plurihormonal Pit-1 lineage adenomas

scientific article published on 8 January 2016

Sp1-mediated transcriptional control of fibroblast growth factor receptor 4 in sarcomas of skeletal muscle lineage

scientific article

Spuriously Elevated Serum IGF-1 in Adult Individuals with Delayed Puberty: A Diagnostic Pitfall

scientific article

Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

scientific article

Targeted expression of a human pituitary tumor–derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

Targeting N-cadherin through fibroblast growth factor receptor-4: distinct pathogenetic and therapeutic implications

scientific article published on 20 July 2006

Temporal trends in thyroid cancer incidence in California-letter

scientific article published in November 2014

The Classification of Pituitary Tumors: An Update

The Diagnosis and Clinical Significance of Paragangliomas in Unusual Locations

The Endocrine System

The FGFR4-G388R single-nucleotide polymorphism alters pancreatic neuroendocrine tumor progression and response to mTOR inhibition therapy

scientific article

The Obesity Epidemic

scientific article published on 06 February 2012

The PI3K/AKT/mTOR pathway in the pathophysiology and treatment of pituitary adenomas

scientific article

The Pathophysiology of Pituitary Tumors

The Rationale of Patients with Early-Stage Papillary Thyroid Cancer for Accepting or Rejecting Radioactive Iodine Remnant Ablation

scientific article published on 01 February 2013

The Role of Mediators of Cell Invasiveness, Motility, and Migration in the Pathogenesis of Silent Corticotroph Adenomas

article

The breast cancer susceptibility gene product fibroblast growth factor receptor 2 serves as a scaffold for regulation of NF-κB signaling

scientific article

The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes

retracted scientific article published on June 2013

The cancer/testis antigen melanoma-associated antigen-A3/A6 is a novel target of fibroblast growth factor receptor 2-IIIb through histone H3 modifications in thyroid cancer

scientific article published on August 2007

The cost of medical care for the acromegalic patient

scientific article published on 13 October 2006

The emerging role of the Ikaros stem cell factor in the neuroendocrine system

scientific article published on 30 May 2008

The epigenetic landscape of differentiated thyroid cancer

scientific article

The impact of thyroid cancer and post-surgical radioactive iodine treatment on the lives of thyroid cancer survivors: a qualitative study

scientific article

The implication of somatotroph adenoma phenotype to somatostatin analog responsiveness in acromegaly

scientific article published on 23 August 2005

The influence of growth hormone status on physical impairments, functional limitations, and health-related quality of life in adults

scientific article

The melanoma-associated antigen A3 mediates fibronectin-controlled cancer progression and metastasis

scientific article published in October 2008

The pathogenesis of pituitary tumors

scientific article published on January 2009

The pathogenesis of pituitary tumours

scientific article

The prevalence of pituitary adenomas: a systematic review

scientific article

The retrotransposon gag domain containing protein Rgag4 is an Ikaros target in the pituitary

scientific article published on 14 September 2017

The role of diabetes in acromegaly associated neoplasia

scientific article published on 21 May 2015

The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility

scientific article published on 23 December 2004

Thyroid Cancer Incidence and Endocrinologist Access: A Regional Data Analysis from Ontario, Canada

scientific article published in May 2016

Thyroid cancer is the most common malignancy arising from hormone-producing glands. Preface.

scientific article

Tools for Enhancement and Quality Improvement of Peer Assessment and Clinical Care in Endocrinology and Metabolism

scientific article

Tumor-derived Ikaros 6 acetylates the Bcl-XL promoter to up-regulate a survival signal in pituitary cells

scientific article published on 27 July 2006

Tyrosine kinase receptors as molecular targets in pheochromocytomas and paragangliomas.

scientific article published on 03 January 2014

Unmet Information Needs of Low-Risk Thyroid Cancer Survivors

scientific article published on 15 January 2016

Ventilation threshold as a measure of impaired physical performance in adults with growth hormone excess

scientific article

Vitamin D and its analog EB1089 induce p27 accumulation and diminish association of p27 with Skp2 independent of PTEN in pituitary corticotroph cells.

scientific article published in October 2002

Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and -independent pathways

scientific article published on February 2002

Vitamin D inhibits CEACAM1 to promote insulin/IGF-I receptor signaling without compromising anti-proliferative action

scientific article published on 16 August 2010

Vitamin D3 administration induces nuclear p27 accumulation, restores differentiation, and reduces tumor burden in a mouse model of metastatic follicular thyroid cancer

scientific article published on 19 August 2004

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