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List of works by Alexis Moreno

5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells

scientific article published on 02 November 2018

Atomic modelling and systematic mutagenesis identify residues in multiple drug binding sites that are essential for drug resistance in the major Candida transporter Cdr1.

scientific article

Cdr1p highlights the role of the non-hydrolytic ATP-binding site in driving drug translocation in asymmetric ABC pumps

scientific article published on 14 November 2019

Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties

scientific article published on 31 August 2017

Molecular Basis of Substrate Polyspecificity of the Candida albicans Mdr1p Multidrug/H+ Antiporter.

scientific article published on 13 January 2018

Monoterpene indole alkaloid azine derivatives as MDR reversal agents.

scientific article published on 2 December 2017

Optimizing the flavanone core toward new selective nitrogen-containing modulators of ABC transporters.

scientific article published on 23 March 2018

PDR-like ABC systems in pathogenic fungi

scientific article published on 25 September 2019

Spontaneous Suppressors against Debilitating Transmembrane Mutants of <i>Ca</i>Mdr1 Disclose Novel Interdomain Communication via Signature Motifs of the Major Facilitator Superfamily

scientific article published on 22 May 2022

Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand

scientific article published on 12 December 2018

W1038 near D-loop of NBD2 is a focal point for inter-domain communication in multidrug transporter Cdr1 of Candida albicans

scientific article published on 30 January 2018

pHluorin enables insights into the transport mechanism of antiporter Mdr1: R215 is critical for drug/H+ antiport.

scientific article published on 18 July 2016

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