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List of works by Mark P Jedrychowski

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

scientific journal article

A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.

scientific article

A tissue-specific atlas of mouse protein phosphorylation and expression

scientific article (publication date: 23 December 2010)

Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes

scientific article

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

scholarly article by Elahu G. Sustarsic published in July 2018

Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex.

scientific article published on 23 January 2014

Cellular spelunking: exploring adipocyte caveolae

scientific article published on 11 May 2007

Characterization of Plasmodium falciparum Atypical Kinase PfPK7- Dependent Phosphoproteome

scientific article published on 20 April 2018

Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

scientific article published on 18 May 2016

Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

scientific article

ERRα Maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-Elevated Melanomas

scientific article published on 8 June 2017

Evaluating multiplexed quantitative phosphopeptide analysis on a hybrid quadrupole mass filter/linear ion trap/orbitrap mass spectrometer

scientific article

Evaluation of HCD- and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics.

scientific article published on 13 September 2011

Fat cells directly sense temperature to activate thermogenesis

scientific article published on July 2013

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

scientific article

Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity

scientific article published on October 2017

Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity

scientific article published on 23 August 2017

Global analysis of protein expression and phosphorylation of three stages of Plasmodium falciparum intraerythrocytic development.

scientific article published on 26 August 2013

Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis

scientific article

Human DDX3 functions in translation and interacts with the translation initiation factor eIF3

scientific article

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

scientific article

Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses

scientific article published on 20 August 2012

Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells.

scientific article

Large-scale characterization of HeLa cell nuclear phosphoproteins

scientific article

Lipid droplet meets a mitochondrial protein to regulate adipocyte lipolysis.

scientific article published on 2 November 2011

Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation

scientific article published on 26 August 2016

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes

scientific article

Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis

scientific journal article

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

scientific journal article

Multiplexed Isobaric Tag-Based Profiling of Seven Murine Tissues Following In Vivo Nicotine Treatment Using a Minimalistic Proteomics Strategy.

scientific article

Neutrophil elastase cleaves VEGF to generate a VEGF fragment with altered activity

scientific article published on 09 January 2009

Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes

scientific article published on 29 March 2018

Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.

scientific article

Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling

scientific article

Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.

scientific article

REMOVED: Identification of a unique molecular and functional microglia signature in health and disease

article

Role of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytes

scientific journal article

Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes.

scientific article published on March 2017

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

scientific article

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.

scientific article

The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator

scientific article published on 28 March 2016

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

scientific journal article

The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

scientific article

The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.

scientific article published on 8 November 2012

Thrap3 docks on phosphoserine 273 of PPARγ and controls diabetic gene programming

scientific article

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction

scientific article

eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference.

scientific article published on 28 May 2015