Search filters

List of works by Bruce J Aronow

A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome

scientific article

A Novel Pkhd1 Mutation Interacts with the Nonobese Diabetic Genetic Background To Cause Autoimmune Cholangitis

scientific article

A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development

scientific article published on 8 January 2016

A catalogue of gene expression in the developing kidney

scientific article published on November 1, 2003

A core program of gene expression characterizes cancer metastases

scientific article published on 2 November 2017

A gene expression atlas of early craniofacial development

scientific article published on 26 April 2014

A mouse model of familial hypertrophic cardiomyopathy caused by a alpha-tropomyosin mutation

scientific article published in September 2003

A thrombospondin-dependent pathway for a protective ER stress response

scientific article

Absence of poly(ADP-ribose)polymerase-1 alters nuclear factor-kappa B activation and gene expression of apoptosis regulators after reperfusion injury

scientific article published on May 1, 2003

Access and use of the GUDMAP database of genitourinary development

scientific article

Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

scientific article

Activation of a novel long-chain free fatty acid generation and export system in mitochondria of diabetic rat hearts

scientific article published on 19 July 2006

Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer

scientific article published on 01 April 2008

Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

scientific article published in March 2019

Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma

scientific article published in February 2005

Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinoma.

scientific article published on 27 July 2013

An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

scientific article published on September 11, 2003

An overview of custom array sequencing

scientific article published on April 2009

Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment

scientific article published on 6 June 2009

Analysis of the biliary transcriptome in experimental biliary atresia

scientific article published in August 2005

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo

scientific article published in January 2004

Apolipoprotein J/clusterin prevents a progressive glomerulopathy of aging

scientific article

Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution

article

Atlas of gene expression in the developing kidney at microanatomic resolution

scientific article

Automatic disease stage classification of glioblastoma multiforme histopathological images using deep convolutional neural network.

scientific article

Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data.

scientific article

Blockade of chronic type I interferon signaling to control persistent LCMV infection

scientific article published on April 2013

Bridging the gap between systems biology and medicine

scientific article published on 29 September 2009

C-fos regulates neuropeptide Y expression in mouse dentate gyrus

scientific article

Calcineurin Abeta gene targeting predisposes the myocardium to acute ischemia-induced apoptosis and dysfunction

scientific article published on 13 November 2003

Calcineurin Links Mitochondrial Elongation with Energy Metabolism

scientific article

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

scientific article published on 28 October 2009

Canonical genetic signatures of the adult human brain

scientific article

Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

article

Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart

scientific journal article

Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts

scientific article published on March 2009

Cellular expression patterns of genes upregulated in murine and human colonic neoplasms

scientific article published on 7 January 2008

Characterization of stable, constitutively expressed, chromosomal green and red fluorescent transcriptional fusions in the select agent bacterium, Francisella tularensis Schu S4 and the surrogate type B live vaccine strain (LVS).

scientific article published on 13 July 2013

Chromatin-associated APC regulates gene expression in collaboration with canonical WNT signaling and AP-1

article

CisMols Analyzer: identification of compositionally similar cis-element clusters in ortholog conserved regions of coordinately expressed genes.

scientific article

Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients with Crohn's Disease

scientific article published on 15 February 2018

Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates

scientific article published on 17 March 2003

Clusterin increases post-ischemic damages in organotypic hippocampal slice cultures

scientific article published on 28 June 2008

Clusterin is not essential for androgen-regulated involution and regeneration of the normal mouse prostate

scientific article published on 01 September 2006

Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease

scientific journal article

Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation

scientific article

Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development

scientific article published on 11 April 2006

Computational approaches for human disease gene prediction and ranking

scientific article published on January 2014

Computational drug repositioning through heterogeneous network clustering

scientific article

Concerns over interspecies transcriptional comparisons in mice and humans after trauma

scientific article published on 11 July 2013

Construction and characterization of stable, constitutively expressed, chromosomal green and red fluorescent transcriptional fusions in the select agents, Bacillus anthracis, Yersinia pestis, Burkholderia mallei, and Burkholderia pseudomallei

scientific article

Control of Bcl-2 expression by reactive oxygen species

scientific article

Coordinate expression of regulatory genes differentiates embryonic and perinatal forms of biliary atresia

scientific article

Correction: Disease candidate gene identification and prioritization using protein interaction networks

article

Corrigendum. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

scientific article published on 2 March 2015

Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma

scientific article published on April 2009

Critical role for transcription factor AP-2alpha in human trophoblast differentiation

scientific article published on 17 June 2004

Cyclin D1 is a selective modifier of androgen-dependent signaling and androgen receptor function

scientific article

Cytomegalovirus infection of human syncytiotrophoblast cells strongly interferes with expression of genes involved in placental differentiation and tissue integrity.

scientific article published in May 2007

DEK over-expression promotes mitotic defects and micronucleus formation.

scientific article

DNA microarray analysis reveals novel gene expression profiles in collagen-induced arthritis

scientific article published on 01 November 2002

Data mining differential clinical outcomes associated with drug regimens using adverse event reporting data

scientific article

Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice

scientific article

Deficiency of clusterin inhibits neointimal hyperplasia after vascular injury.

scientific article

Design and implementation of microarray gene expression markup language (MAGE-ML)

scientific article

Differential coupling of Arg- and Gly389 polymorphic forms of the beta1-adrenergic receptor leads to pathogenic cardiac gene regulatory programs

scientific article published on 29 July 2008

Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: role of poly(ADP-ribose) polymerase-1.

scientific article published on 11 December 2003

Disease candidate gene identification and prioritization using protein interaction networks

scientific article

Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping

scientific article published on 22 June 2015

Divergence of transcriptional landscape occurs early in B cell activation

scientific article published on 14 May 2015

Dynamic changes in gene expression during human trophoblast differentiation

scientific article

Dynamic interaction between T cell-mediated β-cell damage and β-cell repair in the run up to autoimmune diabetes of the NOD mouse

article

Dysfunctional genomics: toward an integrative biology of disease and health--application to IBDs

scientific article published on April 2008

Embrace diversity! Systems genetics-enabled discovery of disease networks

scientific article published on 29 September 2009

Engineered human skin substitutes undergo large-scale genomic reprogramming and normal skin-like maturation after transplantation to athymic mice

scientific article published on 01 October 2009

Environmental impact on direct neuronal reprogramming in vivo in the adult brain

scientific article published on January 2013

Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis

scientific article

Erratum to: Access and Use of the GUDMAP Database of Genitourinary Development

article

Erratum: Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics

scientific article published on 9 February 2016

Erratum: Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling

scientific article published in October 2017

Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity

scientific article published on 25 July 2003

Essential role of clusterin in pancreas regeneration

scientific article published on February 2, 2011

Evolutionarily Conserved Noncoding DNA

Experimental comparison and cross-validation of the Affymetrix and Illumina gene expression analysis platforms

scientific article

Expression of plasma membrane receptor genes during megakaryocyte development

scientific article

Expression profiles of 109 apoptosis pathway-related genes in 82 mouse tissues and experimental conditions

scientific article published in September 2002

Functional evolution of the p53 regulatory network through its target response elements

scholarly article

G-CSF drives a posttraumatic immune program that protects the host from infection

scientific article published on 27 January 2014

GUDMAP – An Online GenitoUrinary Resource

GUDMAP – An Online GenitoUrinary Resource

GUDMAP: the genitourinary developmental molecular anatomy project

scientific article published on 20 February 2008

Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin.

scientific article

Gene expression microarray data analysis of decidual and placental cell differentiation.

scientific article

Gene expression profile analysis of mouse colon embryonic development

scientific journal article

Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury

scientific article published on 15 September 2005

Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets

scientific article published on July 2009

Genes that confer the identity of the renin cell

scientific article

Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse

scientific article published on 21 August 2015

Genetic induction of proinflammatory immunity in children with biliary atresia

scientific article published in November 2002

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

scientific article

Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling

scientific article published on 14 June 2007

Genetic profiling reveals global changes in multiple biological pathways in the hearts of Na, K-ATPase alpha 1 isoform haploinsufficient mice

scientific article published in January 2005

Genetic susceptibility to nickel-induced acute lung injury

scientific article published in June 2003

Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome

scientific article

Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock

scientific article

Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells

scientific article

Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells

scientific article published on 27 September 2013

GenomeTrafac: a whole genome resource for the detection of transcription factor binding site clusters associated with conventional and microRNA encoding genes conserved between mouse and human gene orthologs

scientific article published on 18 December 2006

Genomic analysis of alachlor-induced oncogenesis in rat olfactory mucosa

scientific journal article

Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia

scientific article published in June 2002

Genomics of the periinfarction cortex after focal cerebral ischemia

scientific article

Global expression analysis of gene regulatory pathways during endocrine pancreatic development

scientific article published on 3 December 2003

Global gene expression profile progression in Gaucher disease mouse models

scientific article published on January 11, 2011

Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.

scientific article

Heat shock-initiated apoptosis is accelerated and removal of damaged cells is delayed in the testis of clusterin/ApoJ knock-out mice

scientific article published in April 2002

High-throughput detection of mutations responsible for childhood hearing loss using resequencing microarrays

scientific article

Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1.

scientific article published in December 2004

Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy

scientific article published on 30 August 2008

Human coronary artery perivascular adipocytes overexpress genes responsible for regulating vascular morphology, inflammation, and hemostasis

scientific article published on 04 June 2013

Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9.

scientific article published on September 2005

IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival.

scientific article published on 26 October 2015

Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease

scientific article

Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease.

scientific article published on 02 September 2013

Identifying disease-causal genes using Semantic Web-based representation of integrated genomic and phenomic knowledge

scientific article published on 23 August 2008

Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis

scientific article

Improved human disease candidate gene prioritization using mouse phenotype

scientific article

Independent and overlapping transcriptional activation during liver development and regeneration in mice

scientific article published on 01 March 2002

Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships

scientific article

Inhibition of nitric oxide restores surfactant gene expression following nickel-induced acute lung injury.

scientific article published in February 2003

Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium

scientific article

Integrating neighbor clustering, coexpression clustering and subsystems analysis to define dynamic changes in regulatory networks associated with group A streptococcal sociomicrobiology and niche adaptation

scientific article published on 23 July 2010

Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene

scientific article

Intrinsic Age-Dependent Changes and Cell-Cell Contacts Regulate Nephron Progenitor Lifespan

scientific article published in October 2015

KIT blockade is sufficient for donor hematopoietic stem cell engraftment in Fanconi anemia mice

scientific article published on 20 December 2016

Keloid-derived keratinocytes exhibit an abnormal gene expression profile consistent with a distinct causal role in keloid pathology.

scientific article published in July 2013

LMO7 mediates cell-specific activation of the Rho-myocardin-related transcription factor-serum response factor pathway and plays an important role in breast cancer cell migration

scientific article

Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues

scientific article

Large-scale reprogramming of cranial neural crest gene expression by retinoic acid exposure

scientific article published in October 2004

LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56.

scientific article published on December 2016

Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas

scientific article

Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.

scholarly article

Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development

scientific article

MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia

scientific article

MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.

scientific article

Maternal influences on the transmission of leukocyte gene expression profiles in population samples from Brisbane, Australia

scientific article (publication date: 31 December 2010)

MiR-223 deficiency increases eosinophil progenitor proliferation

scientific article published on 16 January 2013

MicroRNA activation signature in patients with hemophagocytic lymphohistiocytosis and reversibility with disease-specific therapy.

scientific article published on 17 July 2015

MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers

scientific article

MicroRNA-21 Limits In Vivo Immune Response-Mediated Activation of the IL-12/IFN-γ Pathway, Th1 Polarization, and the Severity of Delayed-Type Hypersensitivity

scientific article published on August 17, 2011

Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout

scientific article published on 25 June 2013

Microarray analysis of focal segmental glomerulosclerosis

scientific article published in July 2004

Microarray analysis of gene expression during early stages of mild and severe cardiac hypertrophy

scientific article published on 01 August 2006

Microarray analysis of gene expression in cultured skin substitutes compared with native human skin

scientific article published in December 2005

Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system

scientific article

Microarray-based discovery of highly expressed olfactory mucosal genes: potential roles in the various functions of the olfactory system

scientific article published on 16 December 2003

Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease

Microevolution of group A streptococci in vivo: capturing regulatory networks engaged in sociomicrobiology, niche adaptation, and hypervirulence

scientific article

Mining human phenome to investigate modularity of complex disorders

scientific article published on March 1, 2008

Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

scientific article

Modulation of HCV replication after combination antiretroviral therapy in HCV/HIV co-infected patients.

scientific article

Modulation of chromatin position and gene expression by HDAC4 interaction with nucleoporins

scientific journal article

Molecular engineering and validation of an oncolytic herpes simplex virus type 1 transcriptionally targeted to midkine-positive tumors

scientific article published on July 2010

Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives

scientific article

Multiple interactions between the alpha 2C- and beta1-adrenergic receptors influence heart failure survival

scientific article

Myc-transformed epithelial cells down-regulate clusterin, which inhibits their growth in vitro and carcinogenesis in vivo.

scientific article

Myocyte Enhancer Factors 2A and 2C Induce Dilated Cardiomyopathy in Transgenic Mice

scientific article published in Journal of Biological Chemistry

Neural system-enriched gene expression: relationship to biological pathways and neurological diseases.

scientific article published on 08 July 2004

Nonproteolytic properties of murine alternatively spliced tissue factor: implications for integrin-mediated signaling in murine models

scientific article

Novel genes and functional relationships in the adult mouse gastrointestinal tract identified by microarray analysis

scientific article published on 01 May 2002

Novel resequencing chip customized to diagnose mutations in patients with inherited syndromes of intrahepatic cholestasis

scientific article published on 21 October 2006

Onecut-2 knockout mice fail to thrive during early postnatal period and have altered patterns of gene expression in small intestine

scientific article

PRECISION MEDICINE: DATA AND DISCOVERY FOR IMPROVED HEALTH AND THERAPY.

scientific article

Parsing the roles of the transcription factors GATA-4 and GATA-6 in the adult cardiac hypertrophic response

scientific article

Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells

scientific article

Pattern of sequence variation across 213 environmental response genes

scientific article published on 13 September 2004

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

scientific article

Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease

scientific article published on 22 March 2018

PhenoHM: human-mouse comparative phenome-genome server

scientific article

Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci

scientific journal article

PolyDoms: a whole genome database for the identification of non-synonymous coding SNPs with the potential to impact disease

scientific article

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

scientific article published on March 2017

Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3.1; Pten mutant mice.

scientific article published in October 2007

Protective role of clusterin/apolipoprotein J against neointimal hyperplasia via antiproliferative effect on vascular smooth muscle cells and cytoprotective effect on endothelial cells.

scientific article published on 20 August 2009

RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis.

scientific article published on 20 June 2007

Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target

scientific article published on July 18, 2012

Reconstructing differentiation networks and their regulation from time series single cell expression data

scientific article published on 9 January 2018

Red Blood Cell Dysfunction Induced by High-Fat Diet: Potential Implications for Obesity-Related Atherosclerosis.

scientific article published on 14 October 2015

Response to Letter Regarding Article "Transdifferentiation of Human Fibroblasts to Endothelial Cells: Role of Innate Immunity"

scientific article published on 01 October 2015

Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection

scientific article

Retinoid signaling in progenitors controls specification and regeneration of the urothelium

scientific article

SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity.

scientific article published on February 2013

Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice

scientific article published on April 4, 2011

Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo

scientific article

Shared gene expression profiles in developing heart valves and osteoblast progenitor cells

scientific article published on 8 July 2008

Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology

scientific article published on 08 August 2016

Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers.

scientific article published on 26 January 2010

Single-cell analysis of mixed-lineage states leading to a binary cell fate choice.

scientific article published on 31 August 2016

Spatial distribution of marker gene activity in the mouse lung during alveolarization.

scientific article published on 3 November 2018

Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics

scientific article

Staging of biliary atresia at diagnosis by molecular profiling of the liver

scientific article

Structure of the 5′ Portion of the Human Plakoglobin Gene

article

Subfractionation of differentiating human embryonic stem cell populations allows the isolation of a mesodermal population enriched for intermediate mesoderm and putative renal progenitors

scientific article

Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis

scientific article published on July 2009

Sustained astrocytic clusterin expression improves remodeling after brain ischemia.

scientific article published on 10 February 2006

TRIM24 links a non-canonical histone signature to breast cancer

scientific article

Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth

scientific article

Targeted imaging of colonic tumors in smad3-/- mice discriminates cancer and inflammation

scientific article published on 01 April 2007

Temperature-dependent modification and activation of B-MYB: implications for cell survival

scientific article published on 23 December 2004

Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice

scientific article

The FaceBase Consortium: a comprehensive program to facilitate craniofacial research

scientific article

The GUDMAP database--an online resource for genitourinary research

scientific article

The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer

scientific article published on December 2008

The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis

scientific article published on January 2013

The differential effect of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers with respect to foot ulcer and limb amputation in those with diabetes

scientific article

The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression

scientific article published on 07 June 2007

The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor

scientific article

The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in mice

scientific article published on 14 January 2007

The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer

scientific article

The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5.

scientific article published on 10 May 2016

Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity

scientific article published on 16 December 2013

Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling

scientific article published on 12 June 2017

ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems

scientific article

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

scientific article

ToppMiR: ranking microRNAs and their mRNA targets based on biological functions and context

scientific article

Transcript signatures in experimental asthma: identification of STAT6-dependent and -independent pathways

scientific article published on 01 February 2004

Transcriptional adaptation to cystic fibrosis transmembrane conductance regulator deficiency

scientific article

Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors.

scientific article

Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer

scientific article published on January 2007

Transcriptional response to persistent beta2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility.

scientific article published on 18 July 2006

Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease

scientific article published on 14 August 2017

Transcriptome signature of irreversible senescence in human papillomavirus-positive cervical cancer cells

scientific article

Transdifferentiation of human fibroblasts to endothelial cells: role of innate immunity

scientific article published on 30 October 2014

Translational profiles of medullary myofibroblasts during kidney fibrosis.

scientific article

Unbiased analysis of RB-mediated transcriptional repression identifies novel targets and distinctions from E2F action.

scientific article

Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung

scientific article published on 26 February 2009

Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis

scholarly article

Using Systems Biology-based Analysis Approaches to Identify Mechanistically Significant Adverse Drug Reactions: Pulmonary Complications from Combined Use of Anti-TNFα Agents and Corticosteroids

scientific article published on 18 March 2013

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

scientific article published in August 2007

Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner

scientific article published on 5 September 2013

Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis

scientific article published on 19 April 2018

Wnt/beta-catenin signaling is required for development of the exocrine pancreas

scientific journal article

ailSemantic Web-based data representation and reasoning applied to disease mechanism and pharmacology

scholarly article published November 2007

beta-Catenin/Wnt signaling regulates expression of the membrane type 3 matrix metalloproteinase in gastric cancer

scientific article published on May 2006

mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.

scientific article published on 25 April 2012

p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation

scientific article published on 8 February 2017

p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche.

scientific article