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List of works by Hyae Gyeong Cheon

2-O-carboxymethylpyrogallol derivatives as PTP1B inhibitors with antihyperglycemic activity

scientific article published on 15 August 2007

5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubes

scientific article published on 10 July 2017

A novel PPARgamma agonist, KR62776, suppresses RANKL-induced osteoclast differentiation and activity by inhibiting MAP kinase pathways

scientific article

Activating transcription factor-3 induction is involved in the anti-inflammatory action of berberine in RAW264.7 murine macrophages

scientific article published on 23 June 2016

Angiotensin AT1 receptor antagonism by losartan stimulates adipocyte browning via induction of apelin

scientific article published on 24 August 2020

Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb

scientific article published on May 2007

Anti-angiogenic action of PPARγ ligand in human umbilical vein endothelial cells is mediated by PTEN upregulation and VEGFR-2 downregulation

scientific article

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone (KR-66344).

scientific article

Antiangiogenic effect of rosiglitazone is mediated via peroxisome proliferator-activated receptor gamma-activated maxi-K channel opening in human umbilical vein endothelial cells

scientific article published on 9 March 2006

Antiobesity effects of melanin-concentrating hormone receptor 1 (MCH-R1) antagonists

scientific article published on January 2012

Apoptotic action of peroxisome proliferator-activated receptor-gamma activation in human non small-cell lung cancer is mediated via proline oxidase-induced reactive oxygen species formation

scientific article published on 29 May 2007

Application of the ferrous oxidation-xylenol orange assay for the screening of 5-lipoxygenase inhibitors

scientific article published on 13 January 2006

Author Correction: Telmisartan induces browning of fully differentiated white adipocytes via M2 macrophage polarization

scientific article published on 04 February 2020

B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation

scientific article (publication date: 31 March 2009)

Baicalein protects rat insulinoma INS-1 cells from palmitate-induced lipotoxicity by inducing HO-1

scientific article

Bortezomib attenuates palmitic acid-induced ER stress, inflammation and insulin resistance in myotubes via AMPK dependent mechanism

scientific article

COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model

scholarly article

Cell-based assay for screening 11beta-hydroxysteroid dehydrogenase 1 inhibitors

scientific article

Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028

scientific article published on 12 June 2006

Clomiphene promotes browning of white adipocytes via casein kinase-2 inhibition

scientific article published on 08 August 2019

Determination of a novel phosphodiesterase4 inhibitor, 3-[1-(3cyclopropylmethoxy-4-difluoromethoxybenzyl)-1H-pyrazol-3-yl]-benzoic acid (PDE-423) in rat plasma using liquid chromatography-tandem mass spectrometry

scientific article

Differential anti-proliferative actions of peroxisome proliferator-activated receptor-gamma agonists in MCF-7 breast cancer cells

scientific article published on 27 June 2006

Discovery of (2-fluoro-benzyl)-(2-methyl-2-phenethyl-2H-chromen-6-yl)-amine (KRH-102140) as an orally active 5-lipoxygenase inhibitor with activity in murine inflammation models

scientific article published on 5 January 2011

Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects

scientific article published on 04 December 2020

Discovery of a novel orally active PDE-4 inhibitor effective in an ovalbumin-induced asthma murine model

scientific article

Discovery of a novel protein tyrosine phosphatase-1B inhibitor, KR61639: potential development as an antihyperglycemic agent

scientific article published on February 2004

Discovery of cyclicsulfonamide derivatives as 11 beta-hydroxysteroid dehydrogenase 1 inhibitors

scientific article

EK-6136 (3-methyl-4-(O-methyl-oximino)-1-phenylpyrazolin-5-one): a novel Cdc25B inhibitor with antiproliferative activity

scientific article published in December 2005

Foenumoside B isolated from Lysimachia foenum-graecum extract suppresses LPS-induced inflammatory response via NF-κB/AP-1 inactivation in murine macrophages and in endotoxin-induced shock model

scientific article published on 18 May 2018

Glucose intolerance in young TallyHo mice is induced by leptin-mediated inhibition of insulin secretion

scientific article published on 2 November 2005

Heparan Sulfate Proteoglycan Modulates Keratinocyte Growth Factor Signaling through Interaction with both Ligand and Receptor

article

Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity

scientific article published on 17 July 2010

Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice

scientific article

In vitro metabolism of a new cardioprotective agent, KR-33028 in the human liver microsomes and cryopreserved human hepatocytes

scientific article

Indenone derivatives: a novel template for peroxisome proliferator-activated receptor gamma (PPARgamma) agonists

scientific article published on July 2006

Inhibition of dipeptidyl peptidase IV by novel inhibitors with pyrazolidine scaffold

scientific article published in July 2005

Inhibitory effect of leptin on rosiglitazone-induced differentiation of primary adipocytes prepared from TallyHO/Jng mice

scientific article published on 23 February 2011

Involvement of Prolyl Hydroxylase Domain Protein in the Rosiglitazone-Induced Suppression of Osteoblast Differentiation

scientific article published in 2015

KR-62436, 6-{2-[2-(5-cyano-4,5-dihydropyrazol-1-yl)-2-oxoethylamino]ethylamino}nicotinonitrile, is a novel dipeptidyl peptidase-IV (DPP-IV) inhibitor with anti-hyperglycemic activity

scientific article

KR-62980: a novel peroxisome proliferator-activated receptor gamma agonist with weak adipogenic effects

scientific article published on 12 May 2006

LC-MS/MS identification of in vitro metabolites of a new H+/K+ ATPase inhibitor, KR-60436 produced by rat and human liver microsomes

scientific article published in June 2002

Latest research and development trends in non-insulin anti-diabetics

scientific article published on 11 February 2013

Lead discovery of quinoxalinediones as an inhibitor of dipeptidyl peptidase-IV (DPP-IV) by high-throughput screening

scientific article published in May 2004

Leptin inhibits rosiglitazone-induced adipogenesis in murine primary adipocytes

scientific article

Liver glucokinase can be activated by peroxisome proliferator-activated receptor-gamma.

scientific article published on February 2004

Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance

scientific article

Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction.

scientific article

Neuroprotective effects of KR-62980, a new PPARγ agonist, against chemical ischemia–reperfusion in SK-N-SH cells ⬇️

scientific article published on November 25, 2010

PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives

scientific article

Phosphatase and tensin homolog deleted on chromosome 10 suppression is an important process in peroxisome proliferator-activated receptor-gamma signaling in adipocytes and myotubes

scientific article published on 02 March 2007

Preclinical pharmacokinetics of PDE-310, a novel PDE4 inhibitor

scientific article published on 27 December 2010

Promising strategies for obesity pharmacotherapy: melanocortin-4 (MC-4) receptor agonists and melanin concentrating hormone (MCH) receptor-1 antagonists

scientific article published on January 2009

Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12.

scientific article published on 12 February 2014

Protective effects of arachidonic acid against palmitic acid-mediated lipotoxicity in HIT-T15 cells.

scientific article published on 28 December 2011

Protective effects of pyrrolidine dithiocarbamate against airway inflammation in the ovalbumin-induced mouse model

scientific article published on 15 June 2008

Pyrazolidine derivatives with heteroaryl urea as dipeptidyl peptidase IV inhibitors

scientific article published in August 2005

Roflumilast inhibits lipopolysaccharide-induced inflammatory mediators via suppression of nuclear factor-kappaB, p38 mitogen-activated protein kinase, and c-Jun NH2-terminal kinase activation

scientific article published on 26 August 2005

Selective inhibition of activated stellate cells and protection from carbon tetrachloride-induced liver injury in rats by a new PPARgamma agonist KR62776.

scientific article published on 30 March 2010

Small intestine submucosa sponge for in vivo support of tissue-engineered bone formation in the presence of rat bone marrow stem cells

scientific journal article

Suppression of Adipocyte Differentiation by Foenumoside B from Lysimachia foenum-graecum Is Mediated by PPARγ Antagonism

scientific article

Synthesis and DP-IV inhibition of cyano-pyrazoline derivatives as potent anti-diabetic agents

scientific article published in September 2004

Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents

scientific article

Synthesis and biological evaluation of N-aryl-4-aryl-1,3-thiazole-2-amine derivatives as direct 5-lipoxygenase inhibitors.

scientific article

Synthesis and biological evaluation of dimeric cinnamaldehydes as potent antitumor agents

scientific article published on 15 December 2005

Synthesis and biological evaluation of glucagon-like peptide-1 receptor agonists

scientific article

Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors

scientific article

Synthesis and biological evaluation of pyrazoline analogues with beta-amino acyl group as dipeptidyl peptidase IV inhibitors

scientific article

Synthesis and evaluation of pyrazolidine derivatives as dipeptidyl peptidase IV (DP-IV) inhibitors

scientific article published in March 2005

Synthesis and structure-activity relationship of novel indene N-oxide derivatives as potent peroxisome proliferator activated receptor gamma (PPARgamma) agonists

scientific article published on 30 June 2007

Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors

scientific article

Telmisartan induces browning of fully differentiated white adipocytes via M2 macrophage polarization

scientific article published in Scientific Reports

The role of prolyl hydroxylase domain protein (PHD) during rosiglitazone-induced adipocyte differentiation.

scientific article published on 12 December 2013

Topical application of liposomal cobalamin hydrogel for atopic dermatitis therapy

scientific article published on 01 June 2011

Topical effects of roflumilast on 1-chloro-2,4-dinitrobenzene-induced atopic dermatitis-like skin lesions in NC/Nga mice

scientific article published on December 2010

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