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List of works by Kun-Liang Guan

A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.

scientific article

Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis

scientific article

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

scientific article published in Nature Communications

Cell type-dependent function of LATS1/2 in cancer cell growth

scientific article published on 10 December 2018

Colonic epithelium rejuvenation through YAP/TAZ.

scientific article published on 27 December 2017

EIF3H orchestrates Hippo pathway-mediated oncogenesis via catalytic control of YAP stability

scientific article published on 08 April 2020

Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells

scientific article published on 27 January 2021

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Heat stress activates YAP/TAZ to induce the heat shock transcriptome

scientific article published on 16 November 2020

Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth

scientific article published on 12 December 2019

Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma.

scientific article published on 16 January 2018

Osmotic stress-induced phosphorylation by NLK at Ser128 activates YAP.

scientific article published on 15 December 2016

Publisher Correction: Heat stress activates YAP/TAZ to induce the heat shock transcriptome

scientific article published on 11 December 2020

Publisher Correction: STRIPAK integrates upstream signals to initiate the Hippo kinase cascade

scientific article published on 01 February 2020

Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation

scientific article

SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.

scientific article published on 28 February 2018

STRIPAK integrates upstream signals to initiate the Hippo kinase cascade

scientific article published on 02 December 2019

Structural insights into TSC complex assembly and GAP activity on Rheb

scientific article published on 12 January 2021

The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis

scientific article published on 07 October 2019

Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER<sup>+</sup> breast cancer

scientific article published on 25 February 2022

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity

scientific article published on 11 June 2018

YAP/TAZ phase separation for transcription

scientific article published on 01 April 2020

mTOR as a central hub of nutrient signalling and cell growth

scientific article published on 02 January 2019

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