List of works - Wei-Chen Chang

A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases

scientific article published on 07 March 2019

Elucidating reaction pathway of decarboxylation-assisted olefination catalyzed by a mononuclear non-heme iron enzyme

scientific article published on 05 November 2018

Enzymatic Chemistry of Cyclopropane, Epoxide, and Aziridine Biosynthesis ⬇️

scientific article published on October 21, 2011

Epoxidation Catalyzed by the Nonheme Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, AsqJ: Mechanistic Elucidation of Oxygen Atom Transfer by a Ferryl Intermediate

scientific article published on 16 March 2020

Evidence for Radical-Mediated Catalysis by HppE: A Study Using Cyclopropyl and Methylenecyclopropyl Substrate Analogues ⬇️

scientific article published on September 24, 2012

In Vitro Stepwise Reconstitution of Amino Acid Derived Vinyl Isocyanide Biosynthesis: Detection of an Elusive Intermediate

scientific article published on 17 February 2017

Installation of the Ether Bridge of Lolines by the Iron- and 2-Oxoglutarate-Dependent Oxygenase, LolO: Regio- and Stereochemistry of Sequential Hydroxylation and Oxacyclization Reactions.

scientific article published on 14 March 2018

Mechanistic Investigation of Oxidative Decarboxylation Catalyzed by Two Iron(II)- and 2-Oxoglutarate-Dependent Enzymes

scientific article published on 13 March 2018

Mechanistic Studies of an IspH‐Catalyzed Reaction: Implications for Substrate Binding and Protonation in the Biosynthesis of Isoprenoids ⬇️

scientific article published on October 24, 2011

Nucleophilic Participation of Reduced Flavin Coenzyme in Mechanism of UDP-galactopyranose Mutase ⬇️

scientific article published on December 20, 2011

Optimized Substrate Positioning Enables Switches in the C-H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase

scientific article published on 4 September 2024

Pathway from N-alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases

scientific article published on 19 February 2020

Reaction Mechanism of a Nonheme Iron Enzyme Catalyzed Oxidative Cyclization via C-C Bond Formation

scientific article published on 14 December 2018

Reaction of HppE with Substrate Analogues: Evidence for Carbon–Phosphorus Bond Cleavage by a Carbocation Rearrangement ⬇️

scientific article published on May 23, 2013

Repurposing Nonheme Iron Hydroxylases To Enable Catalytic Nitrile Installation through an Azido Group Assistance

scientific article published on 18 February 2019

Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by its Dimanganese Cofactor.

scientific article published on 2 April 2018

Study of IspH, a Key Enzyme in the Methylerythritol Phosphate Pathway Using Fluoro-Substituted Substrate Analogues ⬇️

scientific article published on October 7, 2011

Substrate Conformation Correlates with the Outcome of Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions

scientific article published on 11 June 2018

Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of α-Heteroatom Assistance

scientific article published on 04 June 2018

Visualizing the Reaction Cycle in an Iron(II)- and 2-(Oxo)-glutarate-Dependent Hydroxylase

scientific article published on 20 August 2017

List of works by Wei-Chen Chang