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List of works by Rex Pratt

A Lysine-Targeted Affinity Label for Serine-β-Lactamase Also Covalently Modifies New Delhi Metallo-β-lactamase-1 (NDM-1)

scientific article published on 07 June 2019

A New Covalent Inhibitor of Class C β-Lactamases Reveals Extended Active Site Specificity

scientific article published on 11 December 2015

A thiono-beta-lactam substrate for the beta-lactamase II of Bacillus cereus. Evidence for direct interaction between the essential metal ion and substrate

scientific article published on March 1989

Crystal Structures of Complexes of Bacterial dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle

scientific article

Crystal Structures of Covalent Complexes of β-Lactam Antibiotics with Escherichia coli Penicillin-Binding Protein 5: Toward an Understanding of Antibiotic Specificity ⬇️

scientific article published on September 21, 2010

Crystal structure of a complex between the Actinomadura R39 DD-peptidase and a peptidoglycan-mimetic boronate inhibitor: interpretation of a transition state analogue in terms of catalytic mechanism

scientific article

Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide

scientific article

Deacylation transition states of a bacterial DD-peptidase

scientific article published on October 2006

Dual substrate specificity of Bacillus subtilis PBP4a

scientific article published on 5 April 2013

Effect of the 3'-leaving group on turnover of cephem antibiotics by a class C beta-lactamase

scientific article published on April 1989

Evidence for an oxyanion hole in serine beta-lactamases and DD-peptidases

scientific article published on December 1988

Evidence from a mutant beta-lactamase for the mechanism of beta-lactamase-catalysed depsipeptide aminolysis

scientific article published on March 1991

Inactivation of the Enterobacter cloacae P99 beta-lactamase by a fluorescent phosphonate: direct detection of ligand binding at the second site

scientific article published in March 1995

Inhibition of Bacterial DD-Peptidases (Penicillin-Binding Proteins) in Membranes and in Vivo by Peptidoglycan-Mimetic Boronic Acids ⬇️

scientific article published on March 23, 2012

Inhibition of beta-lactamases by monocyclic acyl phosph(on)ates

scientific article

Inhibition of class D beta-lactamases by diaroyl phosphates

scientific article

Inhibition of dd-Peptidases by a Specific Trifluoroketone: Crystal Structure of a Complex with the Actinomadura R39 dd-Peptidase ⬇️

scientific article published on March 13, 2013

Inhibition of serine beta-lactamases by vanadate-catechol complexes

scientific article published on 15 August 2008

Interactions of "bora-penicilloates" with serine β-lactamases and DD-peptidases

scientific article published on 10 October 2014

Interactions of cephalosporins with the Streptomyces R61 DD-transpeptidase/carboxypeptidase. Influence of the 3'-substituent

scientific article published on August 1986

Kinetic Evidence for a Second Ligand Binding Site on Streptococcus pneumoniae Penicillin-Binding Protein 2x.

scientific article

Kinetics and mechanism of the hydrolysis of depsipeptides catalyzed by the beta-lactamase of Enterobacter cloacae P99

scientific article published on 01 March 1996

Kinetics of Reactions of the Actinomadura R39 dd-Peptidase with Specific Substrates ⬇️

scientific article published on December 23, 2010

Kinetics of turnover of cefotaxime by the Enterobacter cloacae P99 and GCl beta-lactamases: two free enzyme forms of the P99 beta-lactamase detected by a combination of pre- and post-steady state kinetics

scientific article published in March 2004

Mechanism of Inhibition of the Class C β-Lactamase of Enterobacter cloacae P99 by Cyclic Acyl Phosph(on)ates: Rescue by Return ⬇️

scientific article published on October 31, 2001

Mechanism of inhibition of the PC1 beta-lactamase of Staphylococcus aureus by cephalosporins: importance of the 3'-leaving group

scientific article published on February 1985

Mechanism of reaction of acyl phosph(on)ates with the beta-lactamase of Enterobacter cloacae P99.

scientific article published in April 2001

Nucleophilic re-activation of the PC1 beta-lactamase of Staphylococcus aureus and of the DD-peptidase of Streptomyces R61 after their inactivation by cephalosporins and cephamycins

scientific article published on September 1987

Relative specificities of a series of beta-lactam-recognizing enzymes towards the side-chains of penicillins and of acyclic thioldepsipeptides

scientific article published on September 1994

Substrate Specificity of Low-Molecular Mass Bacterial dd-Peptidases ⬇️

scientific article published on October 27, 2011

The D-methyl group in beta-lactamase evolution: evidence from the Y221G and GC1 mutants of the class C beta-lactamase of Enterobacter cloacae P99.

scientific article published in May 2005

The perfect penicillin? Inhibition of a bacterial DD-peptidase by peptidoglycan-mimetic beta-lactams

scientific article

Transpeptidation reactions of a specific substrate catalyzed by the Streptomyces R61 DD-peptidase: the structural basis of acyl acceptor specificity

scientific article published in August 2005

Transpeptidation reactions of a specific substrate catalyzed by the streptomyces R61 DD-peptidase: characterization of a chromogenic substrate and acyl acceptor design

scientific article published in August 2005

Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin-Binding Protein ⬇️

scientific article published on June 24, 2011

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