List of works by Laura M Yerges-Armstrong

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

article

A Common Variant in the SETD7 Gene Predicts Serum Lycopene Concentrations

scientific article published on 6 February 2016

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A noncoding variant near PPP1R3B promotes liver glycogen storage and MetS, but protects against myocardial infarction

scientific article published on 24 November 2020

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

scientific article published on January 2013

AP2 suppresses osteoblast differentiation and mineralization through down-regulation of Frizzled-1.

scientific article

Adipose tissue and volumetric bone mineral density of older Afro-Caribbean men.

scientific article

Assessment of gene-by-sex interaction effect on bone mineral density

scientific article (publication date: October 2012)

Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes

scientific article published on 01 August 2018

Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits

scientific article published on 10 March 2016

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study ⬇️

scientific article published on 23 February 2017

Association analyses of 47,500 individuals identifies six fracture loci and 82 BMD loci clustering in biological pathways that regulate osteoblast and osteoclast activity

Association analysis of 33 lipoprotein candidate genes in multi-generational families of African ancestry.

scientific article

Association analysis of BMD-associated SNPs with knee osteoarthritis

scientific article

Association analysis of WNT10B with bone mass and structure among individuals of African ancestry

scientific article

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent

scientific article published on 04 April 2013

Association of the CPT1B gene with skeletal muscle fat infiltration in Afro-Caribbean men.

scientific article

Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification

scientific article

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

Candidate gene analysis of femoral neck trabecular and cortical volumetric bone mineral density in older men.

scientific article

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

scientific article (publication date: 2013)

Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry.

scientific article published on 11 October 2016

Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent

scientific article published on 16 July 2013

Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation

scientific article

Conference Scene: Lessons learned from the 5th Statistical Analysis Workshop of the Pharmacogenetics Research Network

scientific article published on 01 March 2010

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

scientific article published on 17 December 2015

Decreased bone mineral density in subjects carrying familial defective apolipoprotein B-100.

scientific article published on 08 October 2013

Development of a physiology-directed population pharmacokinetic and pharmacodynamic model for characterizing the impact of genetic and demographic factors on clopidogrel response in healthy adults

scientific article published on 30 October 2015

Differences in geometric strength at the contralateral hip between men with hip fracture and non-fractured comparators

scientific article published on 05 December 2019

Discovery and replication of several loci significantly associated with lean body mass: a large meta-analysis of genome wide association studies (GWAS) from the 'charge' and 'gefos' consortia

Disentangling the genetics of lean mass

article

E2F1 effects on osteoblast differentiation and mineralization are mediated through up-regulation of frizzled-1.

scientific article published on 24 June 2013

Effectiveness of clopidogrel dose escalation to normalize active metabolite exposure and antiplatelet effects in CYP2C19 poor metabolizers

scientific article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

scientific article published on 21 October 2020

Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation

scientific article

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Factors influencing longitudinal changes of circulating liver enzyme concentrations in subjects randomized to placebo in four clinical trials

scientific article published on 29 November 2018

From Genotype to Phenotype: Nonsense Variants in SLC13A1 Are Associated with Decreased Serum Sulfate and Increased Serum Aminotransferases

scientific article published on 13 July 2016

Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population

scientific article published on 3 July 2017

Functional and association analysis of frizzled 1 (FZD1) promoter haplotypes with femoral neck geometry

scientific article

Functional characterization of genetic variation in the Frizzled 1 (FZD1) promoter and association with bone phenotypes: more to the LRP5 story?

scientific article published on January 2009

Gene Expression Differences Between Offspring of Long-Lived Individuals and Controls in Candidate Longevity Regions: Evidence for PAPSS2 as a Longevity Gene

scientific article published on 19 February 2016

Genetic Determinants of Radiographic Knee Osteoarthritis in African Americans

scientific article published on 15 September 2017

Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction

scientific article published on 25 September 2015

Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men.

scientific article published on 09 December 2010

Genetic epidemiology of osteoarthritis: recent developments and future directions

scientific article published on March 2013

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

scientific article

Genetic variation at NCAN locus is associated with inflammation and fibrosis in non-alcoholic fatty liver disease in morbid obesity

scientific article published on 10 April 2013

Genome-Wide Association Study of Radiographic Knee Osteoarthritis in North American Caucasians

scientific article

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response

scientific article published on 15 February 2017

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

scientific article

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups

scientific article published on 26 February 2009

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

scientific article

Genotype, resilience and function and physical activity post hip fracture

scientific article published on 23 March 2019

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men

scientific article

Identification and association analysis of single nucleotide polymorphisms in the human noggin (NOG) gene and osteoporosis phenotypes

scientific article published on 9 January 2009

Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data

scientific article published on 21 January 2019

Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes

scientific article published on 18 April 2019

Integration of pharmacometabolomic and pharmacogenomic approaches reveals novel insights into antiplatelet therapy

scientific article

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Mapping Genes in Isolated Populations: Lessons from the Old Order Amish

article

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm

scientific article published on 09 April 2013

Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women

scientific article published on March 2013

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

scientific article published on 30 October 2020

Meta‐Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

scientific article published on 19 March 2019

Molecular variation in neuropeptide Y and bone mineral density among men of African ancestry

scientific article published on 29 October 2009

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

scientific article published on 21 November 2016

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

scientific article

Mutation analysis of patients with Hermansky-Pudlak syndrome: a frameshift hot spot in the HPS gene and apparent locus heterogeneity

scientific article

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 25 February 2019

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes

scientific article

Older men who sustain a hip fracture experience greater declines in bone mineral density at the contralateral hip than non-fractured comparators

scientific article published on 24 October 2017

Osteoarthritis susceptibility genes continue trickling in

scientific article

Oxaliplatin-Induced Peripheral Neuropathy and Identification of Unique Severity Groups in Colorectal Cancer

scientific article published on 23 July 2017

Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study

scientific article published on 26 October 2015

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Pain, Genes, and Function in the Post-Hip Fracture Period

scientific article published on June 2016

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability

scientific article

Phenome-wide association study using research participants' self-reported data provides insight into the Th17 and IL-17 pathway

scientific article published in November 2017

Prospective Evaluation of Genetic Variation in Platelet Endothelial Aggregation Receptor 1 Reveals Aspirin-Dependent Effects on Platelet Aggregation Pathways

scientific article published on 11 January 2017

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article

Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics

scientific article published on 11 June 2013

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare coding variants and X-linked loci associated with age at menarche

scientific article

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

scientific article published on 5 December 2016

Sex-specific effects of serum sulfate level and SLC13A1 nonsense variants on DHEA homeostasis.

scientific article

TM6SF2 rs58542926 impacts lipid processing in liver and small intestine.

scientific article published on 27 December 2016

The 7Q31 locus, containing WNT16, is associated with bone mineral density, osteoporotic fracture and bone strength

The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations

scientific article published on 22 December 2016

The Impact of Genetics on Physical Resilience and Successful Aging

scientific article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The Interplay of Genetics, Behavior, and Pain with Depressive Symptoms in the Elderly

scientific article

The Pharmacogenomics of Anti-Platelet Intervention (PAPI) Study: Variation in Platelet Response to Clopidogrel and Aspirin

scientific article published on 15 September 2015

The genetics of bone loss: challenges and prospects

scientific article

Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1.

scientific article

Tumor necrosis factor alpha can contribute to focal loss of cartilage in osteoarthritis

scientific article published on 01 May 2000

Variant sequences of the Hexokinase II gene in familial NIDDM

scientific article published on 01 March 1996

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

scientific article published in July 2012

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