List of works - Karen White

2,4-Diaminothienopyrimidines as orally active antimalarial agents

scientific article published on 28 January 2014

3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential

scientific article

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

scientific article

A triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor (DSM421) with improved drug-like properties for treatment and prevention of malaria

scientific article (publication date: 9 December 2016)

Accuracy and reproducibility of fetal-fraction measurement using relative quantitation at polymorphic loci with microarray.

scientific article published on 26 February 2018

Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp. ⬇️

scientific article

Cell-free DNA analysis after reduction in multifetal pregnancy

scientific article published on 01 January 2020

Cell-free DNA testing for prenatal aneuploidy assessment: an analysis of international professional society statements

scientific article published on 12 June 2020

Hemolysis and Fetal Fraction in Cell-Free DNA Blood Collection Tubes for Noninvasive Prenatal Testing

scientific article published on 01 April 2020

Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice

scientific article published on April 2009

Isoxazolopyrimidine-Based Inhibitors of Dihydroorotate Dehydrogenase with Antimalarial Activity

Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria

scientific article published on 06 April 2020

Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice

scientific article

Maternal age trends support uptake of non-invasive prenatal testing (NIPT) in the low-risk population

scientific article published on 20 June 2018

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1.

scientific article

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

scientific article published on 14 September 2016

Quinolone-3-diarylethers: a new class of antimalarial drug.

scientific article published in March 2013

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

scientific article

Targeted cell-free DNA analysis with microarray quantitation for assessment of fetal sex and sex chromosome aneuploidy risk

scientific article published on 21 November 2017

Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity

scientific article published on 29 April 2016

List of works by Karen White

2,4-Diaminothienopyrimidines as orally active antimalarial agents

3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

A triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor (DSM421) with improved drug-like properties for treatment and prevention of malaria

Accuracy and reproducibility of fetal-fraction measurement using relative quantitation at polymorphic loci with microarray.

Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp. ⬇️

Cell-free DNA analysis after reduction in multifetal pregnancy

Cell-free DNA testing for prenatal aneuploidy assessment: an analysis of international professional society statements

Hemolysis and Fetal Fraction in Cell-Free DNA Blood Collection Tubes for Noninvasive Prenatal Testing

Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice

Isoxazolopyrimidine-Based Inhibitors of Dihydroorotate Dehydrogenase with Antimalarial Activity

Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria

Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice

Maternal age trends support uptake of non-invasive prenatal testing (NIPT) in the low-risk population

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1.

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

Quinolone-3-diarylethers: a new class of antimalarial drug.

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

Targeted cell-free DNA analysis with microarray quantitation for assessment of fetal sex and sex chromosome aneuploidy risk

Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity