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List of works by Subra Kugathasan

A 14-year-old girl with recurrent vulvar abscess

scientific article published on 20 November 2013

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF.

scientific article published on July 2016

A Microbiome Foundation for the Study of Crohn's Disease

scientific article published on March 2017

A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition

scientific article

A gene locus that controls expression of ACE2 in virus infection

scientific article published on 29 April 2020

A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease

scientific article published on 31 March 2021

A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients

scientific article

A practical and novel method to extract genomic DNA from blood collection kits for plasma protein preservation

scientific article published on 18 May 2013

A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease

scientific article

Age of diagnosis influences serologic responses in children with Crohn's disease: a possible clue to etiology?

scientific article published on May 2009

Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

scientific article published in March 2019

Altered intestinal ACE2 levels are associated with inflammation, severe disease and response to anti-cytokine therapy in IBD

scientific article published on 02 November 2020

Analysis of Using the Total White Blood Cell Count to Define Severe New Onset Ulcerative Colitis in Children

scientific article published on 09 June 2020

Analysis of keratin polypeptides 8 and 19 variants in inflammatory bowel disease.

scientific article published on 16 May 2007

Appraisal of the pediatric ulcerative colitis activity index (PUCAI)

scientific article published on 01 August 2009

Association Between Plasma Level of Collagen Type III alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn's Disease

scientific article published on 10 September 2018

Association of Crohn's disease, thiopurines, and primary epstein-barr virus infection with hemophagocytic lymphohistiocytosis

scientific article

Association of Linear Growth Impairment in Pediatric Crohn's Disease and a Known Height Locus: A Pilot Study ⬇️

scientific article published on September 15, 2010

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation

scientific article published on 16 February 2019

Body mass index in children with newly diagnosed inflammatory bowel disease: observations from two multicenter North American inception cohorts.

scientific article published on 24 August 2007

Bowel Location Rather Than Disease Subtype Dominates Transcriptomic Heterogeneity in Pediatric IBD

scientific article published on 01 August 2018

CARD15 and IL23R influences Crohn's disease susceptibility but not disease phenotype in a Brazilian population

scientific article published on 01 May 2008

CARD15 gene mutations and risk for early surgery in pediatric-onset Crohn's disease

scientific article published on 01 November 2004

Challenges in IBD Research: Pragmatic Clinical Research

scientific article published on 01 May 2019

Challenges in IBD research: update on progress and prioritization of the CCFA's research agenda

scientific article published on March 2013

Challenges in pediatric inflammatory bowel disease

scientific article published on September 2006

Characterization of Stool Virome in Children Newly Diagnosed With Moderate to Severe Ulcerative Colitis

scientific article published on 01 September 2019

Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans

scientific article

Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients with Crohn's Disease

scientific article published on 15 February 2018

Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study

scientific article published on 29 March 2019

Combination Therapy in Pediatric Inflammatory Bowel Disease: Yes, No, Maybe

scientific article published in October 2017

Commentaries on "Workshop report: developing a pediatric inflammatory bowel diseases network and data platform in Canada": pediatric inflammatory bowel disease networks: raising the bar.

scientific article

Common NOD2 risk variants in African Americans with Crohn's disease are due exclusively to recent Caucasian admixture

scientific article

Common and rare variant prediction and penetrance of IBD in a large, multi-ethnic, health system-based biobank cohort

scientific article published on 24 December 2020

Common variants at five new loci associated with early-onset inflammatory bowel disease

scientific article

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

scientific article

Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and White children with Crohn's disease

scientific article published on July 2005

Comparison of magnetic resonance enterography with endoscopy, histopathology, and laboratory evaluation in pediatric Crohn disease.

scientific article published on August 2012

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course

article

Contribution of OCTN variants within the IBD5 locus to pediatric onset Crohn's disease

scientific article published on 01 June 2006

Contribution of higher risk genes and European admixture to Crohn's disease in African Americans

scientific article published on 12 March 2012

Corrigendum. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

scientific article published on 2 March 2015

Corticosteroid Therapy in the Age of Infliximab: Acute and 1-Year Outcomes in Newly Diagnosed Children With Crohn’s Disease

scientific article published on 24 July 2006

Course and Treatment of Perianal Disease in Children Newly Diagnosed with Crohnʼs Disease

scientific article published on 01 March 2009

Crohn's Disease and Genetic Hitchhiking at IBD5 ⬇️

scientific article published on August 4, 2011

DLG5 R30Q variant is a female-specific protective factor in pediatric onset Crohn's disease

scientific article published on 11 December 2006

Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance

scientific article published on 09 October 2020

Dermatologic manifestations of Crohn disease in children: response to infliximab

scientific article published on 01 August 2003

Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America

scientific article published on May 2007

Disease-specific regulation of gene expression in a comparative analysis of juvenile idiopathic arthritis and inflammatory bowel disease.

scientific article published on 27 June 2018

Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation

scientific article published on 14 September 2018

Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping

scientific article published on 22 June 2015

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease

scientific article

Dynamics of metatranscription in the inflammatory bowel disease gut microbiome

scientific article

Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease

scientific article

Early Onset Granulomatous Colitis Associated with a Mutation in NCF4 Resolved with Hematopoietic Stem Cell Transplantation

scientific article published on 23 April 2019

Effect of early immunomodulator use in moderate to severe pediatric Crohn disease

scientific article

Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis

scientific article

Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in wisconsin: a statewide population-based study ⬇️

scientific article published on October 1, 2003

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Established genetic risk factors do not distinguish early and later onset Crohn's disease

scientific article published on October 2009

Evaluation of the Pediatric Crohn Disease Activity Index: A Prospective Multicenter Experience

article

Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men

article

Evolution of Pediatric Inflammatory Bowel Disease Unclassified (IBD-U): Incorporated With Serological and Gene Expression Profiles

scientific article published on 01 September 2018

Exclusive and partial enteral nutrition for Crohn's disease - Authors' reply

scientific article published in September 2017

Exome sequencing identifies a novel FOXP3 mutation in a 2-generation family with inflammatory bowel disease

scientific article

Extraintestinal manifestations of pediatric inflammatory bowel disease and their relation to disease type and severity

scientific article published in August 2010

Factors That Determine Risk for Surgery in Pediatric Patients With Crohn's Disease

scientific article published on 31 May 2010

Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study

scientific article published on 19 September 2017

Familial Association of Granulocyte-Macrophage Colony Stimulating Factor Autoantibodies in Inflammatory Bowel Disease.

scientific article published on 5 December 2017

Fecal calprotectin is useful in predicting disease relapse in pediatric inflammatory bowel disease

scientific article published in May 2008

Free and Bioavailable 25-Hydroxyvitamin D Concentrations are Associated With Disease Activity in Pediatric Patients With Newly Diagnosed Treatment Naïve Ulcerative Colitis.

scientific article published in February 2018

Functional genomics and its implications for molecular medicine

scientific article published on October 2006

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease

scientific article published on 01 February 2019

Genetic determinants of pediatric inflammatory bowel disease: is age of onset genetically determined?

scientific article published on 24 September 2009

Genetic sharing and heritability of paediatric age of onset autoimmune diseases.

scientific article

Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort.

scientific article published on 28 March 2018

Genetics of Inflammatory Bowel Diseases

scientific article published on 06 August 2015

Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.

scientific article published on 28 September 2016

Genome-wide association identifies diverse causes of common variable immunodeficiency

scientific article published on 17 April 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

Growth Abnormalities Persist in Newly Diagnosed Children With Crohn Disease Despite Current Treatment Paradigms

scientific article published on 01 February 2009

Guidelines for immunizations in patients with inflammatory bowel disease

scientific article published in September 2004

Health-related quality of life in the first year after a diagnosis of pediatric inflammatory bowel disease

article

Hidradenitis suppurativa and pediatric Crohn disease

scientific article published in April 2015

Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed With Ulcerative Colitis.

scientific article published on 31 August 2017

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

IBD LIVE Case Series--Case 3: Very Early-Onset Inflammatory Bowel Disease: When Genetic Testing Proves Beneficial

scientific article published on 01 December 2015

IBD Serology and Disease Outcomes in African Americans With Crohn's Disease

scientific article published in December 2017

IBD: Genetic differences in Crohn's disease susceptibility and outcome

scientific article published on 08 March 2017

IL-10R Polymorphisms Are Associated with Very-early-onset Ulcerative Colitis ⬇️

scientific article published on January 1, 2013

Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease

scientific article published on 7 March 2016

Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes

scientific article

Improved risk prediction for Crohn's disease with a multi-locus approach ⬇️

scientific article published on March 22, 2011

Improvement in Biomarkers of Bone Formation During Infliximab Therapy in Pediatric Crohn's Disease: Results of the REACH Study

article

Incidence, clinical characteristics, and natural history of pediatric IBD in Wisconsin: a population-based epidemiological study

scientific article published on May 2013

Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease

scientific article

Increased immune reactivity predicts aggressive complicating Crohn's disease in children

scientific article published on 10 July 2008

Induction and Maintenance Therapy With Infliximab for Children With Moderate to Severe Ulcerative Colitis ⬇️

scientific article published on December 8, 2011

Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children

scientific article published on 3 December 2006

Inflammatory bowel disease

scientific article published on 01 February 2004

Inflammatory bowel disease--environmental modification and genetic determinants

scientific article published on August 2006

Infliximab Is Not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease

scientific article published on 10 February 2017

Infliximab Optimization Based on Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease

scientific article published on 21 June 2016

Infliximab therapy in children with concurrent perianal Crohn disease: observations from REACH

scientific article published on 01 August 2009

Intercenter variation in initial management of children with Crohn's disease

scientific article published on 01 July 2007

Laboratory values for children with newly diagnosed inflammatory bowel disease

scientific article

Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn's disease and murine colitis.

scientific article

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

scientific article

Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease.

scientific article published in January 2018

Long-term outcome of maintenance infliximab therapy in children with Crohnʼs disease

scientific article published on 01 June 2009

Machine learning identifies novel blood protein predictors of penetrating and stricturing complications in newly diagnosed paediatric Crohn's disease

scientific article published on 01 November 2020

Magnetic Resonance Enterography Healing and Magnetic Resonance Enterography Remission Predicts Improved Outcome in Pediatric Crohn Disease

scientific article

Management of Acute Severe Colitis in Children With Ulcerative Colitis in the Biologics Era.

scientific article published on May 2016

Management of Anti-drug Antibodies to Biologic Medications in Children With Inflammatory Bowel Disease

scientific article published on 01 November 2019

Markers That Differentiate Early from Late IBD ⬇️

scientific article published on July 12, 2012

Medical radiation exposure in children with inflammatory bowel disease estimates high cumulative doses

scientific article published on January 13, 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

scientific article

Methotrexate following unsuccessful thiopurine therapy in pediatric Crohn's disease

scientific article published in December 2007

Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease

Molecular stratification of Crohn's disease by chemokine receptors: fractalkine receptor polymorphisms define a fibrostenosing ileal subgroup

scientific article published on 01 January 2006

Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients

scientific article

Mucosal Healing in Clinical Practice: A Single-Center Pediatric IBD Experience

scientific article published on 20 June 2017

Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease

scientific article published on 08 August 2020

Multi-Site Comparison of Patient, Parent, and Pediatric Provider Perspectives on Transition to Adult Care in IBD.

scientific article published on 3 February 2018

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

scientific article published on 29 May 2019

Multidimensional Prognostic Risk Assessment Identifies Association Between IL12B Variation and Surgery in Crohn’s Disease ⬇️

scientific article published on July 1, 2013

Multilocus Heterotopic Gastric Mucosa of Ileum Masquerading as VEOIBD in a Newborn

scientific article published on 01 April 2019

Natalizumab therapy for moderate to severe Crohn disease in adolescents

scientific article

Neutrophil GM-CSF signaling in inflammatory bowel disease patients is influenced by non-coding genetic variants

scientific article published on 24 June 2019

Nonclassic Inflammatory Bowel Disease in Young Infants: Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome, and Other Disorders.

scientific article published on February 2017

PTSD is associated with increased DNA methylation across regions ofHLA-DPB1 and SPATC1L

scientific article published on 02 November 2020

PUFAs and IBD: Is There a Relationship?

scientific article published on 6 October 2017

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

scientific article

Pediatric Inflammatory Bowel Disease Clinical Innovations Meeting of the Crohn's & Colitis Foundation: Charting the Future of Pediatric IBD

scientific article published on 01 January 2019

Pediatric inflammatory bowel disease: clinical and molecular genetics

scientific article published on November 2007

Pediatric inflammatory bowel disease: highlighting pediatric differences in IBD

scientific article published on 01 January 2010

Pediatric inflammatory bowel disease: highlighting pediatric differences in IBD.

scientific article

Pediatric onset Crohnʼs colitis is characterized by genotype-dependent age-related susceptibility

scientific article published on 01 December 2007

Performance of Interferon-Gamma Release Assays for Tuberculosis Screening in Pediatric Inflammatory Bowel Disease

scientific article published on 01 October 2019

Performance of Interferon-gamma Release Assays for Tuberculosis Screening in Pediatric Inflammatory Bowel Disease

scientific article published on 01 December 2019

Pilot Study Evaluating Efficacy of 2 Regimens for Hypovitaminosis D Repletion in Pediatric Inflammatory Bowel Disease

scientific article published on 20 July 2015

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

scientific article published on March 2017

Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets.

scientific article published on 29 January 2019

Progress in basic inflammatory bowel disease research

scientific article published on August 2007

Real-time tool to display the predicted disease course and treatment response for children with Crohn's disease

scientific article

Reduced expression of COVID-19 host receptor, ACE2 is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn′s disease

scientific article published on 23 April 2020

Reply

scientific article published on 05 May 2017

Response to Biologics Delay Progression of Crohn's Disease in Children but Not Early Surgery

scientific article published on 01 June 2018

Response to the Letter from Drs. Greenstein and Brown

article

Retrospective Evaluation of the Safety and Effect of Adalimumab Therapy (RESEAT) in pediatric Crohn's disease

scientific article published on September 2009

Rising incidence of inflammatory bowel disease in young children: What does the future hold?

scientific article

Role of genetics in pediatric inflammatory bowel disease

scientific article

Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn’s disease in children: REACH open-label extension ⬇️

scientific article published on January 18, 2011

Searching for new clues in inflammatory bowel disease: tell tales from pediatric IBD natural history studies

scientific article published on 09 September 2008

Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children

scientific article published on 01 May 2018

Serologic, but Not Genetic, Markers Are Associated With Impaired Anthropometrics at Diagnosis of Pediatric Crohn's Disease

scientific article published on 01 November 2019

Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease

scientific article published on 01 May 2019

Severe colitis in children

scientific article

Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of response

scientific article published on 26 February 2010

Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

scientific article published on 29 August 2019

Stressful life events, depression, and the moderating role of psychophysiological reactivity in patients with pediatric inflammatory bowel disease

scientific article published on 30 November 2020

Targeted Gene Sequencing in Children with Crohn's Disease and Their Parents: Implications for Missing Heritability

scientific article published on 30 August 2018

The Age of Gene Discovery in Very Early Onset Inflammatory Bowel Disease ⬇️

scientific article published on June 21, 2012

The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children

scientific article published on 28 September 2018

The Natural History of Corticosteroid Therapy for Ulcerative Colitis in Children

scientific article published on 03 July 2006

The microbiome in inflammatory bowel disease: from prevailing clinical evidence to future possibilities

article

The treatment-naive microbiome in new-onset Crohn's disease

scientific article

Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease

scientific article published on 14 August 2017

Two-Year-Old With a Limp and Suspected Nonaccidental Injury

scientific article published on 01 July 2018

Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

scientific article published in Nature Communications

Ureteropelvic junction obstruction: an overlooked cause of cyclic vomiting

scientific article published on 01 April 2002

Use of Reticulocyte Hemoglobin Content in the Assessment of Iron Deficiency in Children With Inflammatory Bowel Disease

scientific article published on 16 July 2016

Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease

scientific article

Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study

scientific article published on 01 June 2019

Vertebral Osteomyelitis Due to Candida parapsilosis in a Child With Crohn Disease While Receiving Anti‐TNF Therapy ⬇️

scientific article published on 01 April 2013

Vitamin D Status Is Associated with Hepcidin and Hemoglobin Concentrations in Children with Inflammatory Bowel Disease

scientific article published on 11 July 2017

Vitamin D status and bone mineral density in African American children with Crohn disease.

scientific article

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