List of works - David M Hougaard

1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex

scientific article published on 11 November 2019

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

scientific article published on 2 December 2017

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

article

A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

scientific article published on 28 January 2019

A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness

scientific article published on 09 March 2020

A large-scale genome-wide association study meta-analysis of cannabis use disorder

scientific article published on 20 October 2020

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population

scientific article published on 11 November 2019

A major role for common genetic variation in anxiety disorders

scientific article published on 20 November 2019

A polygenic resilience score moderates the genetic risk for schizophrenia

scientific article published on 06 September 2019

ASD and ADHD have a similar burden of rare protein-truncating variants

Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression

scientific article published on 06 February 2020

An epigenetic clock for gestational age at birth based on blood methylation data

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Anthropometry in Klinefelter Syndrome - Multifactorial Influences Due to CAG Length, Testosterone Treatment and Possibly Intrauterine Hypogonadism

Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia

scientific article published on 16 May 2020

Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia

scientific article published on 01 November 2019

Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk

scientific article published on 14 September 2011

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Association of the polygenic risk score for schizophrenia with mortality and suicidal behavior - A Danish population-based study.

scientific article published on 06 December 2016

Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants

scientific article published on 25 November 2019

Common risk variants identified in autism spectrum disorder

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

scientific article published on 26 February 2018

Common variants at VRK2 and TCF4 conferring risk of schizophrenia

scientific article published on 26 July 2011

Common variants conferring risk of schizophrenia

scientific article

Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes

Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes

scientific article published in PLoS ONE

Correction: Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorder

scientific article published on 08 December 2020

Delay in blood sampling for routine newborn screening is associated with increased risk of schizophrenia

scientific article published on 24 January 2015

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

scholarly article published 3 June 2017

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

scientific article published on 26 November 2018

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

scientific article published in February 2022

Elevated polygenic burden for autism is associated with differential DNA methylation at birth

scientific article published on 28 March 2018

Exploring Cuba's population structure and demographic history using genome-wide data

scientific article published on 30 July 2018

FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

scientific article

Few differences in cytokines between patients newly diagnosed with type 1 diabetes and their healthy siblings

Foetal oestrogens and autism

scientific article published on 29 July 2019

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

scientific article

Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study

scientific article published on 22 May 2019

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study

scientific article published on 10 June 2020

Genetic liability to ADHD and substance use disorders in individuals with ADHD

scientific article published on 05 December 2019

Genetic liability to major depression and risk of childhood asthma

scientific article published on 28 July 2020

Genetic predictors of educational attainment and intelligence test performance predict voter turnout

scientific article published on 09 November 2020

Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women

scientific article published on 25 November 2020

Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders

scientific article published on 11 November 2019

Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study

article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

scientific article published in October 2013

Genome-wide association study across pediatric central nervous system tumors implicates shared predisposition and points to 1q25.2 (PAPPA2) and 11p12 (LRRC4C) as novel candidate susceptibility loci

scientific article published on 23 November 2020

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy

scientific article published on 9 December 2016

Genome-wide association study implicates CHRNA2 in cannabis use disorder

scientific article published on 17 June 2019

Genome-wide association study implicatesCHRNA2in cannabis use disorder

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

scientific article published on 11 November 2019

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis

scientific article published on 01 January 2019

Gestational age-dependent development of the neonatal metabolome

scientific article published on 17 September 2020

High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA.

scientific article

Identification of common genetic risk variants for autism spectrum disorder

scientific article published on 25 February 2019

Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders

scientific article published on 11 April 2019

Including Classical Galactosaemia in the Expanded Newborn Screening Panel Using Tandem Mass Spectrometry for Galactose-1-Phosphate

scientific article published on 04 May 2019

Influence of Polygenic Risk Scores on the Association Between Infections and Schizophrenia

scientific article published on 19 April 2016

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

scientific article published on 08 October 2019

Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia

scientific article

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

article published in 2018

Levels of adiponectin and leptin at onset of type 1 diabetes have changed over time in children and adolescents

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective

scientific article published in 2022

Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease

Modelling the contribution of family history and variation in single nucleotide polymorphisms to risk of schizophrenia: a Danish national birth cohort-based study

scientific article

Neonatal Levels of Inflammatory Markers and Later Risk of Schizophrenia

Neonatal vitamin D status and risk of schizophrenia: a population-based case-control study

scientific article published on September 2010

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk

article

Pharmacogenetic genotype and phenotype frequencies in a large Danish population-based case-cohort sample

scientific article

Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis.

scientific article published on July 2015

Polygenic Risk and Progression to Bipolar or Psychotic Disorders Among Individuals Diagnosed With Unipolar Depression in Early Life

scientific article published on 14 July 2020

Polygenic risk score, psychosocial environment and the risk of attention-deficit/hyperactivity disorder

scientific article published on 02 October 2020

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.

scientific article published on 15 May 2017

Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders

Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study

scientific article published on 07 June 2018

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

scientific article published on 01 July 2019

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

Reduced neonatal brain-derived neurotrophic factor is associated with autism spectrum disorders

scientific article published on 07 October 2019

Roadmap for a precision-medicine initiative in the Nordic region

scientific article published on 01 June 2019

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease

scientific article published in PLoS ONE

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

scientific article

Short QTc interval in males with klinefelter syndrome-influence of CAG repeat length, body composition, and testosterone replacement therapy.

scientific article published on 23 January 2015

The Duffy-null genotype and risk of infection

scientific article published on 22 September 2020

The association between neonatal vitamin D status and risk of schizophrenia

scientific article published in Scientific Reports

The genetic architecture of sporadic and multiple consecutive miscarriage

scientific article published on 25 November 2020

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

The utility of neonatal dried blood spots for the assessment of neonatal vitamin D status.

scientific article published on May 2010

Variable DNA methylation in neonates mediates the association between prenatal smoking and birth weight

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

scientific article published on 02 September 2019

Vertical Transfer of Metabolites Detectable from Newborn’s Dried Blood Spot Samples Using UPLC-MS: A Chemometric Study

scientific article published in 2022

Vitamin D status during pregnancy and the risk of subsequent postpartum depression: a case-control study

scientific article

List of works by David M Hougaard

1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness

A large-scale genome-wide association study meta-analysis of cannabis use disorder

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population

A major role for common genetic variation in anxiety disorders

A polygenic resilience score moderates the genetic risk for schizophrenia

ASD and ADHD have a similar burden of rare protein-truncating variants

Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression

An epigenetic clock for gestational age at birth based on blood methylation data

Analysis of shared heritability in common disorders of the brain

Anthropometry in Klinefelter Syndrome - Multifactorial Influences Due to CAG Length, Testosterone Treatment and Possibly Intrauterine Hypogonadism

Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia

Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia

Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Association of the polygenic risk score for schizophrenia with mortality and suicidal behavior - A Danish population-based study.

Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants

Common risk variants identified in autism spectrum disorder

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Common variants at VRK2 and TCF4 conferring risk of schizophrenia

Common variants conferring risk of schizophrenia

Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes

Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes

Correction: Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorder

Delay in blood sampling for routine newborn screening is associated with increased risk of schizophrenia

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Elevated polygenic burden for autism is associated with differential DNA methylation at birth

Exploring Cuba's population structure and demographic history using genome-wide data

FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

Few differences in cytokines between patients newly diagnosed with type 1 diabetes and their healthy siblings

Foetal oestrogens and autism

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study

Genetic liability to ADHD and substance use disorders in individuals with ADHD

Genetic liability to major depression and risk of childhood asthma

Genetic predictors of educational attainment and intelligence test performance predict voter turnout

Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women

Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders

Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Genome-wide association study across pediatric central nervous system tumors implicates shared predisposition and points to 1q25.2 (PAPPA2) and 11p12 (LRRC4C) as novel candidate susceptibility loci

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy

Genome-wide association study implicates CHRNA2 in cannabis use disorder

Genome-wide association study implicatesCHRNA2in cannabis use disorder

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

Genome-wide associations for birth weight and correlations with adult disease

Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis

Gestational age-dependent development of the neonatal metabolome

High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA.

Identification of common genetic risk variants for autism spectrum disorder

Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders

Including Classical Galactosaemia in the Expanded Newborn Screening Panel Using Tandem Mass Spectrometry for Galactose-1-Phosphate

Influence of Polygenic Risk Scores on the Association Between Infections and Schizophrenia

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

Levels of adiponectin and leptin at onset of type 1 diabetes have changed over time in children and adolescents

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective

Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease

Modelling the contribution of family history and variation in single nucleotide polymorphisms to risk of schizophrenia: a Danish national birth cohort-based study

Neonatal Levels of Inflammatory Markers and Later Risk of Schizophrenia

Neonatal vitamin D status and risk of schizophrenia: a population-based case-control study

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk

Pharmacogenetic genotype and phenotype frequencies in a large Danish population-based case-cohort sample

Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis.

Polygenic Risk and Progression to Bipolar or Psychotic Disorders Among Individuals Diagnosed With Unipolar Depression in Early Life