Search filters

List of works by Karin E. Bornfeldt

2013 Russell Ross memorial lecture in vascular biology: cellular and molecular mechanisms of diabetes mellitus-accelerated atherosclerosis

scientific article published on April 2014

A Long Road Ahead for Discovering New HDL Metrics That Reflect Cardiovascular Disease Risk

scientific article published in July 2017

A New Treatment Strategy for Diabetic Dyslipidemia?

scientific article published on 01 October 2020

A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome.

scientific article published on 26 February 2018

A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis

scientific article published on 15 November 2017

A Role of the Heme Degradation Pathway in Shaping Prostate Inflammatory Responses and Lipid Metabolism

scientific article published on 05 February 2020

A single second messenger: several possible cellular responses depending on distinct subcellular pools

scientific article published on 01 October 2006

Acyl-CoA Synthetase 1 Is Induced by Gram-negative Bacteria and Lipopolysaccharide and Is Required for Phospholipid Turnover in Stimulated Macrophages ⬇️

scientific article published on February 20, 2013

Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages

scientific article

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity

scientific article

Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficien

scientific article

Albuminuria, the High-Density Lipoprotein Proteome, and Coronary Artery Calcification in Type 1 Diabetes Mellitus

scientific article published on 16 May 2019

An inducible and reversible mouse genetic rescue system

scientific article

Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques

scientific article published on 03 October 2019

Apolipoprotein A1 Forms 5/5 and 5/4 Antiparallel Dimers in Human High-density Lipoprotein

scientific article published on 18 January 2019

Apolipoprotein C3 and apolipoprotein B colocalize in proximity to macrophages in atherosclerotic lesions in diabetes

scientific article published on 08 December 2020

Arterial smooth muscle

scientific article

Association of apolipoprotein C3 with insulin resistance and coronary artery calcium in patients with type 1 diabetes

scientific article published on 31 October 2020

Atherosclerosis: Successes, Surprises, and Future Challenges

scientific article published on February 2016

Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity.

scientific article published on 7 June 2018

Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux

scientific article published on 17 January 2022

Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships

scientific article

Correction: Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity

scientific article published on 05 December 2019

Cyclic AMP-specific phosphodiesterase 4 inhibitors promote ABCA1 expression and cholesterol efflux

scientific article published in January 2002

Cyclic GMP phosphodiesterases and regulation of smooth muscle function

scientific article

Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation

scientific article

Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet.

scientific article published on 15 October 2009

Diabetes Impairs Cellular Cholesterol Efflux from ABCA1 to Small HDL Particles

scientific article published on 21 August 2020

Diabetes and atherosclerosis: is there a role for hyperglycemia?

scientific article

Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions

scientific article published on September 2004

Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1 ⬇️

scientific article published on January 17, 2012

Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys

scientific article

Diabetes-accelerated atherosclerosis and inflammation

scientific article published on October 2008

Diabetic vascular disease and the potential role of macrophage glucose metabolism ⬇️

scientific article published on June 17, 2011

Direct effects of long-chain non-esterified fatty acids on vascular cells and their relevance to macrovascular complications of diabetes

scientific article published on May 2004

Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or progression to advanced plaques?

scientific article published on March 2007

Does Elevated Glucose Promote Atherosclerosis? Pros and Cons

scientific article published on July 2016

Effects of High Fat Feeding and Diabetes on Regression of Atherosclerosis Induced by Low-Density Lipoprotein Receptor Gene Therapy in LDL Receptor-Deficient Mice

scientific article published on 5 June 2015

Emerging Targets for Cardiovascular Disease Prevention in Diabetes

scientific article published on 15 May 2020

Endothelial Acyl-CoA Synthetase 1 Is Not Required for Inflammatory and Apoptotic Effects of a Saturated Fatty Acid-Rich Environment ⬇️

scientific article published on December 13, 2012

Evidence stacks up that endothelial insulin resistance is a culprit in atherosclerosis.

scientific article published on August 2013

GPIHBP1: two get tangled

scientific article published in February 2015

Genetic association of long-chain acyl-CoA synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis

scientific article

Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion

scientific article published on 30 April 2015

Growing evidence for a role for acyl-CoA synthetase 1 in immunometabolism

scientific article published on 03 July 2019

Hematopoietic Cell-Expressed Endothelial Nitric Oxide Protects the Liver From Insulin Resistance

scientific article published on 30 January 2020

High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes

scientific article published on 09 October 2019

High-Density Lipoprotein Function in Cardiovascular Disease and Diabetes Mellitus.

scientific article published in February 2018

Highlighting Residual Atherosclerotic Cardiovascular Disease Risk

scientific article published on 01 January 2019

How Far We Have Come, How Far We Have Yet to Go in Atherosclerosis Research

scientific article published on 23 April 2020

How does diabetes accelerate atherosclerotic plaque rupture and arterial occlusion?

scientific article

Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: potential role of glucose-oxidized LDL.

scientific article published in December 2004

Hypertriglyceridemia and Atherosclerosis: Using Human Research to Guide Mechanistic Studies in Animal Models

scientific article published on 06 August 2020

IGF-I/insulin hybrid receptors in human endothelial cells

scientific article published on 01 January 2005

Impact of Diabetes Mellitus

scientific article published on June 2016

Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes

scientific article published on 11 July 2019

Inflammation and diabetes-accelerated atherosclerosis: myeloid cell mediators.

scientific article

Inflammatory stimuli induce acyl-CoA thioesterase 7 and remodeling of phospholipids containing unsaturated long (≥C20)-acyl chains in macrophages.

scientific article published on 17 April 2017

Integrin alpha(7)beta(1) COMPels smooth muscle cells to maintain their quiescence

scientific article published on February 2010

Intracellular and Intercellular Aspects of Macrophage Immunometabolism in Atherosclerosis

scientific article published on 23 April 2020

Lipids and the endothelium: bidirectional interactions

scientific article

Lipids versus glucose in inflammation and the pathogenesis of macrovascular disease in diabetes

scientific article

Liver Kinase B1 Links Macrophage Metabolism Sensing and Atherosclerosis

scientific article published in October 2017

Long-chain acyl-CoA synthetase 4 modulates prostaglandin E2 release from human arterial smooth muscle cells ⬇️

scientific article published on January 17, 2011

Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics.

scientific article published on 3 April 2018

Macrophage Phenotype and Function in Different Stages of Atherosclerosis

scientific article published on February 2016

Macrophage metalloelastase (MMP12) regulates adipose tissue expansion, insulin sensitivity, and expression of inducible nitric oxide synthase

scientific article

Metabolic Flexibility and Dysfunction in Cardiovascular Cells

scientific article

Microvascular management of systemic insulin sensitivity

scientific article

Modulating the Gut Microbiota Improves Glucose Tolerance, Lipoprotein Profile and Atherosclerotic Plaque Development in ApoE-Deficient Mice

scientific article (publication date: 2016)

Monocytes and Macrophages as Protagonists in Vascular Complications of Diabetes

scientific article published on 14 February 2020

Mouse models for studies of cardiovascular complications of type 1 diabetes

scientific article published on 21 March 2007

Myeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes

scientific article

Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation

scientific article published on 15 August 2018

Novel Reversible Model of Atherosclerosis and Regression Using Oligonucleotide Regulation of the LDL Receptor

scientific article published on 10 January 2018

Novel insights into the role of S100A8/A9 in skin biology ⬇️

scientific article published on 09 August 2012

Nuclear signaling in smooth muscle cells: cyclic nucleotide phosphodiesterase 1A moves in

scientific article published on 01 March 2006

Oleate and linoleate enhance the growth-promoting effects of insulin-like growth factor-I through a phospholipase D-dependent pathway in arterial smooth muscle cells

scientific article

Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways

scientific article

Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease

scientific article published on 01 April 2020

Response by Fotakis et al to Letter Regarding Article, "Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques"

scientific article published on 22 January 2020

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

scientific article

Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes

scientific journal article

Rosiglitazone inhibits acyl-CoA synthetase activity and fatty acid partitioning to diacylglycerol and triacylglycerol via a peroxisome proliferator-activated receptor-gamma-independent mechanism in human arterial smooth muscle cells and macrophages.

scientific article

S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation

scientific article

SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP.

scientific article published on 06 September 2016

Smooth muscle glucose metabolism promotes monocyte recruitment and atherosclerosis in a mouse model of metabolic syndrome

scientific article published on 07 June 2018

TNF-α induces acyl-CoA synthetase 3 to promote lipid droplet formation in human endothelial cells

scientific article published on 13 November 2019

Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis

scientific article

The Remnant Lipoprotein Hypothesis of Diabetes-Associated Cardiovascular Disease

scientific article published in 2022

The cyclin-dependent kinase pathway moves forward

scientific article published on 01 March 2003

The p75 neurotrophin receptor is required for the major loss of sympathetic nerves from islets under autoimmune attack

scientific article

Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice.

scholarly article

Uncomplicating the Macrovascular Complications of Diabetes: The 2014 Edwin Bierman Award Lecture

scientific article published in August 2015

Unique Proteomic Signatures Distinguish Macrophages and Dendritic Cells ⬇️

scientific article published on March 12, 2012

VASP increases hepatic fatty acid oxidation by activating AMPK in mice.

scientific article published on 24 January 2013

Paulina is supported by:

About Paulina

Help