List of works - Yun Li

A comprehensive comparison on cell-type composition inference for spatial transcriptomics data

scientific article published in 2022

A second generation human haplotype map of over 3.1 million SNPs

scientific article

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

scientific article published on 11 September 2020

Age-related DNA hydroxymethylation is enriched for gene expression and immune system processes in human peripheral blood

scientific article published on 26 September 2019

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

scientific article

CUE: CpG impUtation ensemble for DNA methylation levels across the human methylation450 (HM450) and EPIC (HM850) BeadChip platforms

scientific article published on 04 October 2020

Cell-type-specific 3D epigenomes in the developing human cortex

scientific article published on 14 October 2020

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

scientific article

Common variants at 30 loci contribute to polygenic dyslipidemia

scientific article

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

scientific article

From GWAS variant to function: A study of ∼148,000 variants for blood cell traits

scientific article published in 2022

Generalized multi-SNP mediation intersection-union test

scientific article published on 14 December 2020

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.

scientific article

Genome-wide detection and characterization of positive selection in human populations

scientific article

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

scientific article

HPRep: Quantifying Reproducibility in HiChIP and PLAC-Seq Datasets

scientific article published on 17 September 2021

MAPS: Model-based analysis of long-range chromatin interactions from PLAC-seq and HiChIP experiments

scientific article published on 15 April 2019

MRLocus: Identifying causal genes mediating a trait through Bayesian estimation of allelic heterogeneity

scientific article published in 2021

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

scientific article

Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath

scientific article published on 15 September 2021

Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations

scientific article

SAME-clustering: Single-cell Aggregated Clustering via Mixture Model Ensemble

scientific article published on 01 January 2020

Single-cell dual-omics reveals the transcriptomic and epigenomic diversity of cardiac non-myocytes

scientific article published on 01 May 2022

TWO-SIGMA: A novel two-component single cell model-based association method for single-cell RNA-seq data

scientific article published on 29 September 2020

The Association of Epigenetic Age Acceleration and Multimorbidity at Age 90 in the Women’s Health Initiative

scientific article published on 15 September 2022

The genome of a songbird

scientific article

Transcriptome-wide association analysis of brain structures yields insights into pleiotropy with complex neuropsychiatric traits

scientific article published in 2021

Transcriptome-wide association study in UK Biobank Europeans identifies associations with blood cell traits

scientific article published in 2022

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article published on 23 December 2019

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article

List of works by Yun Li

A comprehensive comparison on cell-type composition inference for spatial transcriptomics data

A second generation human haplotype map of over 3.1 million SNPs

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

Age-related DNA hydroxymethylation is enriched for gene expression and immune system processes in human peripheral blood

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

CUE: CpG impUtation ensemble for DNA methylation levels across the human methylation450 (HM450) and EPIC (HM850) BeadChip platforms

Cell-type-specific 3D epigenomes in the developing human cortex

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

Common variants at 30 loci contribute to polygenic dyslipidemia

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

From GWAS variant to function: A study of ∼148,000 variants for blood cell traits

Generalized multi-SNP mediation intersection-union test

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.

Genome-wide detection and characterization of positive selection in human populations

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

HPRep: Quantifying Reproducibility in HiChIP and PLAC-Seq Datasets

MAPS: Model-based analysis of long-range chromatin interactions from PLAC-seq and HiChIP experiments

MRLocus: Identifying causal genes mediating a trait through Bayesian estimation of allelic heterogeneity

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath

Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations

SAME-clustering: Single-cell Aggregated Clustering via Mixture Model Ensemble

Single-cell dual-omics reveals the transcriptomic and epigenomic diversity of cardiac non-myocytes

TWO-SIGMA: A novel two-component single cell model-based association method for single-cell RNA-seq data

The Association of Epigenetic Age Acceleration and Multimorbidity at Age 90 in the Women’s Health Initiative

The genome of a songbird

Transcriptome-wide association analysis of brain structures yields insights into pleiotropy with complex neuropsychiatric traits

Transcriptome-wide association study in UK Biobank Europeans identifies associations with blood cell traits

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations